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KEGG   Panthera tigris altaica (Amur tiger): 102964642
Entry
102964642         CDS       T02988                                 
Symbol
SYK
Name
(RefSeq) spleen associated tyrosine kinase
  KO
K05855  spleen tyrosine kinase [EC:2.7.10.2]
Organism
ptg  Panthera tigris altaica (Amur tiger)
Pathway
ptg04064  NF-kappa B signaling pathway
ptg04072  Phospholipase D signaling pathway
ptg04151  PI3K-Akt signaling pathway
ptg04380  Osteoclast differentiation
ptg04611  Platelet activation
ptg04613  Neutrophil extracellular trap formation
ptg04625  C-type lectin receptor signaling pathway
ptg04650  Natural killer cell mediated cytotoxicity
ptg04662  B cell receptor signaling pathway
ptg04664  Fc epsilon RI signaling pathway
ptg04666  Fc gamma R-mediated phagocytosis
ptg05152  Tuberculosis
ptg05167  Kaposi sarcoma-associated herpesvirus infection
ptg05168  Herpes simplex virus 1 infection
ptg05169  Epstein-Barr virus infection
ptg05171  Coronavirus disease - COVID-19
ptg05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ptg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    102964642 (SYK)
   04072 Phospholipase D signaling pathway
    102964642 (SYK)
   04151 PI3K-Akt signaling pathway
    102964642 (SYK)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102964642 (SYK)
   04613 Neutrophil extracellular trap formation
    102964642 (SYK)
   04650 Natural killer cell mediated cytotoxicity
    102964642 (SYK)
   04662 B cell receptor signaling pathway
    102964642 (SYK)
   04664 Fc epsilon RI signaling pathway
    102964642 (SYK)
   04666 Fc gamma R-mediated phagocytosis
    102964642 (SYK)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102964642 (SYK)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    102964642 (SYK)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    102964642 (SYK)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102964642 (SYK)
   05169 Epstein-Barr virus infection
    102964642 (SYK)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    102964642 (SYK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ptg01001]
    102964642 (SYK)
Enzymes [BR:ptg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     102964642 (SYK)
Protein kinases [BR:ptg01001]
 Non-receptor tyrosine kinases
  SYK family
   102964642 (SYK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 Kdo ABC1
Other DBs
NCBI-GeneID: 102964642
NCBI-ProteinID: XP_015395570
Position
Un
AA seq 471 aa
MPWFHGKISRVESEQIVLIGSKTNGKFLIRDRNDNGSYALCLLHEGKVLHYRIDKDKTGK
LSIPDGKKFDTLWQLVEHYSYKADGLLRVLTVPCQKIGGQTGNINFGARAPLPGPHPATW
SAGGIISRIKSYSFPKPGHRKASTSQGSRPESAVTFNPYEPDRGAWPTDRDAQREALPMD
TEVYESPYADPEEIRPKEVYLDRKLLTLEDNELGSGNFGTVKKGYYQMKKVVKTVAVKIL
KNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNR
HVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADEN
YYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSAM
LEKGERMGCPTGCPREMYELMKLCWTYEVENRPGFAAVELRLRNYYYDVVN
NT seq 1416 nt   +upstreamnt  +downstreamnt
atgccctggttccacggcaaaatctcacgggtcgaatcggagcagattgtcctgatcgga
tccaagacaaatggaaaatttttgatccgggacaggaacgacaacgggtcttacgccctg
tgcctgctgcatgaggggaaggtactgcactaccgcatcgataaggacaaaacggggaag
ctctccatccccgacgggaagaagttcgacacgctctggcagctagtggagcattattct
tataaagcagatgggctgttaagagttcttacagttccgtgtcagaaaattggcgggcag
acaggaaatatcaacttcggagcccgggcgcccctcccaggtccacatcctgcaacatgg
tcagcgggtggaattatctcaagaatcaaatcatactccttcccaaagcctggccacaga
aaggcctccacatcccaagggagccggccagagagcgccgtgaccttcaatccgtacgag
ccggaccgcggggcctggcccacggacagagacgcccagagagaggccttgcccatggac
accgaggtgtatgaaagcccgtatgcggaccccgaggagatcaggcccaaggaagtctac
ctggaccgcaagctgctgaccctggaggacaacgaactgggctctggtaacttcgggacc
gtgaagaagggctactaccagatgaaaaaagtcgtgaaaacggtggctgtgaagattctg
aagaacgaagctaacgaccccgctcttaaagatgagttattagcggaagccaatgtcatg
cagcagctcgataacccctacatcgtgcgcatgattggcatctgtgaagccgagtcctgg
atgctggtgatggagatggcggaactgggtccgctcaacaagtatttacagcagaacagg
cacgtcaaggataagaacatcatagagctggttcatcaggtttctatgggaatgaagtat
ctggaggagagcaattttgtgcacagagatctggcggcaagaaacgtcttgctggttact
caacactatgccaagatcagtgattttggactttccaaagcgctccgtgctgatgaaaac
tactacaaggcccagacccacgggaagtggccggtcaagtggtacgcccccgagtgcatc
aactactacaagttctccagcaagagtgacgtctggagcttcggcgtgttgatgtgggag
gcgttctcctacgggcagaagccgtaccggggcatgaagggaagtgaggtttcggccatg
ctggagaaaggagagagaatggggtgccccacggggtgtccaagggagatgtacgagctg
atgaagctgtgctggacgtatgaggtggagaacaggcccggattcgcagccgtggaactg
cgtctacgcaattattactacgacgtggtcaactaa

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