Entry |
|
Symbol |
HES1, HES-1, HHL, HRY, bHLHb39
|
Name |
(RefSeq) hes family bHLH transcription factor 1
|
KO |
K06054 | hairy and enhancer of split 1 |
|
Organism |
|
Pathway |
hsa04950 | Maturity onset diabetes of the young |
|
Network |
|
Element |
N00086 | Notch signaling pathway |
N00087 | NOTCH-overexpression to Notch signaling pathway |
N00225 | EBV EBNA2 to RBP-Jk-mediated transcription |
N00380 | HPV E6 to Notch signaling pathway |
N00381 | HPV E6 to Notch signaling pathway |
N00382 | HPV E6 to Notch signaling pathway |
|
Brite |
KEGG Orthology (KO) [BR:hsa00001]
09120 Genetic Information Processing
09124 Replication and repair
03460 Fanconi anemia pathway
3280 (HES1)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
3280 (HES1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
3280 (HES1)
09162 Cancer: specific types
05224 Breast cancer
3280 (HES1)
09172 Infectious disease: viral
05169 Epstein-Barr virus infection
3280 (HES1)
05165 Human papillomavirus infection
3280 (HES1)
09167 Endocrine and metabolic disease
04950 Maturity onset diabetes of the young
3280 (HES1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:hsa03000]
3280 (HES1)
03400 DNA repair and recombination proteins [BR:hsa03400]
3280 (HES1)
Transcription factors [BR:hsa03000]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Hairy, Hairy/E(SPL)
3280 (HES1)
DNA repair and recombination proteins [BR:hsa03400]
Eukaryotic type
DSBR (double strand breaks repair)
FA (Fanconi anemia) pathway
FA core complex binding factors
3280 (HES1)
|
SSDB |
|
Motif |
|
Other DBs |
|
Structure |
|
Position |
3:194136148..194138732
|
AA seq |
280 aa
MPADIMEKNSSSPVAATPASVNTTPDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTL
ILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECMNE
VTRFLSTCEGVNTEVRTRLLGHLANCMTQINAMTYPGQPHPALQAPPPPPPGPGGPQHAP
FAPPPPLVPIPGGAAPPPGGAPCKLGSQAGEAAKVFGGFQVVPAPDGQFAFLIPNGAFAH
SGPVIPVYTSNSGTSVGPNAVSPSSGPSLTADSMWRPWRN |
NT seq |
843 nt +upstreamnt +downstreamnt
atgccagctgatataatggagaaaaattcctcgtccccggtggctgctaccccagccagt
gtcaacacgacaccggataaaccaaagacagcatctgagcacagaaagtcatcaaagcct
attatggagaaaagacgaagagcaagaataaatgaaagtctgagccagctgaaaacactg
attttggatgctctgaagaaagatagctcgcggcattccaagctggagaaggcggacatt
ctggaaatgacagtgaagcacctccggaacctgcagcgggcgcagatgacggctgcgctg
agcacagacccaagtgtgctggggaagtaccgagccggcttcagcgagtgcatgaacgag
gtgacccgcttcctgtccacgtgcgagggcgttaataccgaggtgcgcactcggctgctc
ggccacctggccaactgcatgacccagatcaatgccatgacctaccccgggcagccgcac
cccgccttgcaggcgccgccaccgcccccaccgggacccggcggcccccagcacgcgccg
ttcgcgccgccgccgccactcgtgcccatccccgggggcgcggcgccccctcccggcggc
gccccctgcaagctgggcagccaggctggagaggcggctaaggtgtttggaggcttccag
gtggtaccggctcccgatggccagtttgctttcctcattcccaacggggccttcgcgcac
agcggccctgtcatccccgtctacaccagcaacagcggcacctccgtgggccccaacgca
gtgtcaccttccagcggcccctcgcttacggcggactccatgtggaggccgtggcggaac
tga |