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KEGG   Gracilinanus agilis (agile gracile opossum): 123246222
Entry
123246222         CDS       T07702                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
gas  Gracilinanus agilis (agile gracile opossum)
Pathway
gas04010  MAPK signaling pathway
gas04015  Rap1 signaling pathway
gas04218  Cellular senescence
gas04380  Osteoclast differentiation
gas04620  Toll-like receptor signaling pathway
gas04664  Fc epsilon RI signaling pathway
gas04668  TNF signaling pathway
gas04750  Inflammatory mediator regulation of TRP channels
gas04912  GnRH signaling pathway
gas04935  Growth hormone synthesis, secretion and action
gas04936  Alcoholic liver disease
gas05014  Amyotrophic lateral sclerosis
gas05022  Pathways of neurodegeneration - multiple diseases
gas05132  Salmonella infection
gas05135  Yersinia infection
gas05145  Toxoplasmosis
gas05161  Hepatitis B
gas05163  Human cytomegalovirus infection
gas05167  Kaposi sarcoma-associated herpesvirus infection
gas05169  Epstein-Barr virus infection
gas05170  Human immunodeficiency virus 1 infection
gas05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
gas05417  Lipid and atherosclerosis
gas05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:gas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    123246222 (MAP2K6)
   04668 TNF signaling pathway
    123246222 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    123246222 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    123246222 (MAP2K6)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    123246222 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123246222 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    123246222 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    123246222 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    123246222 (MAP2K6)
   05161 Hepatitis B
    123246222 (MAP2K6)
   05163 Human cytomegalovirus infection
    123246222 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123246222 (MAP2K6)
   05169 Epstein-Barr virus infection
    123246222 (MAP2K6)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    123246222 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    123246222 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    123246222 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    123246222 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123246222 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    123246222 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    123246222 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:gas01001]
    123246222 (MAP2K6)
Enzymes [BR:gas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     123246222 (MAP2K6)
Protein kinases [BR:gas01001]
 Serine/threonine kinases: STE group
  STE7 family
   123246222 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 123246222
NCBI-ProteinID: XP_044531088
Position
4:complement(218504409..218562117)
AA seq 362 aa
MGVASQCSFHEDVFLPVALIYQCLHYLLVFFPIGRKRNPGLKIPKEAFEQPQTSSAPPRD
LDSKACISIGDKNFEVKADDLEPIVELGRGAYGVVEKMRHMPSGQIMAVKRIRATVNSQE
QKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGLTIPE
DILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTLGQVKMCDFGISGYLVDSVAKTM
DAGCKPYMAPERINPELNQKGYNVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVE
EPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYAELMQHQFFTLHESKATDAASFVKLIL
GD
NT seq 1089 nt   +upstreamnt  +downstreamnt
atgggggtagccagccagtgtagttttcatgaagatgttttcctgcctgttgctcttatt
taccaatgtcttcactatctcctcgttttctttcccataggcaggaagcggaaccctggg
ttgaagattccaaaagaagcattcgagcaacctcagaccagttcagcacctcctcgtgat
ttagattccaaggcttgcatctcaattggagataagaattttgaagtgaaggctgatgac
ttggagcctatagtagaactgggacgaggtgcttatggggtggtggagaaaatgcgacac
atgcctagtgggcagatcatggcagtgaagcgaatccgagcaactgtgaatagccaggaa
cagaagaggctactgatggacctggatatttccatgaggacagtggattgccctttcaca
gtcaccttttatggtgcactctttcgggagggtgatgtgtggatctgtatggaactcatg
gatacctcactggataagttctacaaacaagtcattgataagggcttaacaatcccagag
gacatcttagggaaaattgcagtttctattgtaaaagccctagaacatttacacagtaaa
ctttctgtcattcatcgagatgttaagccatctaatgtattgatcaatacactaggtcaa
gtgaagatgtgtgattttggtattagtggttacctggtggactctgtggccaaaactatg
gatgcaggatgtaaaccctacatggctcctgaaagaataaatccagaactaaaccagaaa
gggtacaatgtgaaatctgacatttggagcttgggcatcacaatgattgaactggcaatc
cttaggtttccctatgattcctgggggacaccatttcagcagctcaagcaggtggtggaa
gaaccatcacctcaacttccagcagacaagttctcagcagagtttgttgactttacctca
cagtgcttgaagaagaattccaaagaacggccaacatatgcagaacttatgcaacatcaa
tttttcactctgcacgaatccaaagcaacagatgcagcatcttttgtaaaactgattctt
ggagactaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (24)   
   KEGG PATHWAY (24)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (9)   
   Pfam (9)   
All databases (43)   

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