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KEGG   Mustela lutreola (European mink): 131816040
Entry
131816040         CDS       T09578                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
mlk  Mustela lutreola (European mink)
Pathway
mlk04010  MAPK signaling pathway
mlk04015  Rap1 signaling pathway
mlk04218  Cellular senescence
mlk04380  Osteoclast differentiation
mlk04620  Toll-like receptor signaling pathway
mlk04664  Fc epsilon RI signaling pathway
mlk04668  TNF signaling pathway
mlk04750  Inflammatory mediator regulation of TRP channels
mlk04912  GnRH signaling pathway
mlk04935  Growth hormone synthesis, secretion and action
mlk04936  Alcoholic liver disease
mlk05014  Amyotrophic lateral sclerosis
mlk05022  Pathways of neurodegeneration - multiple diseases
mlk05132  Salmonella infection
mlk05135  Yersinia infection
mlk05145  Toxoplasmosis
mlk05161  Hepatitis B
mlk05163  Human cytomegalovirus infection
mlk05167  Kaposi sarcoma-associated herpesvirus infection
mlk05169  Epstein-Barr virus infection
mlk05170  Human immunodeficiency virus 1 infection
mlk05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mlk05417  Lipid and atherosclerosis
mlk05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlk00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    131816040 (MAP2K6)
   04668 TNF signaling pathway
    131816040 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    131816040 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    131816040 (MAP2K6)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    131816040 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    131816040 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    131816040 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    131816040 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    131816040 (MAP2K6)
   05161 Hepatitis B
    131816040 (MAP2K6)
   05163 Human cytomegalovirus infection
    131816040 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    131816040 (MAP2K6)
   05169 Epstein-Barr virus infection
    131816040 (MAP2K6)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    131816040 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    131816040 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    131816040 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    131816040 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    131816040 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    131816040 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    131816040 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mlk01001]
    131816040 (MAP2K6)
Enzymes [BR:mlk01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     131816040 (MAP2K6)
Protein kinases [BR:mlk01001]
 Serine/threonine kinases: STE group
  STE7 family
   131816040 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 131816040
NCBI-ProteinID: XP_059004326
Position
15:complement(10541660..10665246)
AA seq 361 aa
MSQSKGRKRNPGLKIPKEAFEQPQPSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADRFSEEFVDFTSQCLKKNSK
ERPTYPELMDILQFHTAAEEEGASRRHCHGLRMFVRVYAKLHTVCVVFNVVSIYELTQTT
I
NT seq 1086 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaggaagcgaaaccctggccttaaaattccaaaagaagcattt
gaacaacctcagcccagttccacgccacctcgagacttggactctaaagcttgcatttct
attggaaatcagaactttgaggtgaaagcagatgacctggagcccataatggagctgggg
cggggtgcgtacggggtggtggagaagatgcgacacgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacagttaacagccaagagcagaagaggctactgatggatctg
gatatttccatgaggacagtggactgtccttttacggtcaccttttatggcgcactcttc
cgggagggtgatgtttggatttgcatggagctcatggatacgtcgctagataaattctac
aaacaagtgattgataaaggccaaacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcgttagaacacttacacagtaagctgtctgtcattcatcgagacgtc
aaaccttccaatgtgctgatcaacgctcttggccaagtaaagatgtgcgattttggaatc
agtggctaccttgtagactctgttgccaaaactattgacgcaggatgcaaaccgtacatg
gcccctgaaaggataaacccagagctcaatcagaagggatacagtgtaaagtctgacatt
tggagtctgggcatcacaatgatcgagttggctatccttcggtttccctacgactcttgg
ggaactcccttccagcagctcaagcaggtggtagaggagccctcgccacagctcccggcg
gacagattctcggaagagtttgttgactttacctcacagtgcttgaagaagaattccaaa
gaacggccaacatatccagaacttatggatattcttcagtttcatactgctgctgaggag
gaaggagcgagccgccgacactgtcatggtctccggatgtttgtgcgtgtgtatgcaaaa
cttcacactgtgtgtgttgtgttcaatgttgtgtcaatctatgaactgactcaaacaaca
atttga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (24)   
   KEGG PATHWAY (24)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (4)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (10)   
   Pfam (10)   
All databases (50)   

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