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KEGG   Myotis lucifugus (little brown bat): 102426303
Entry
102426303         CDS       T07795                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X2
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
mlf  Myotis lucifugus (little brown bat)
Pathway
mlf04010  MAPK signaling pathway
mlf04015  Rap1 signaling pathway
mlf04218  Cellular senescence
mlf04380  Osteoclast differentiation
mlf04620  Toll-like receptor signaling pathway
mlf04664  Fc epsilon RI signaling pathway
mlf04668  TNF signaling pathway
mlf04750  Inflammatory mediator regulation of TRP channels
mlf04912  GnRH signaling pathway
mlf04935  Growth hormone synthesis, secretion and action
mlf04936  Alcoholic liver disease
mlf05014  Amyotrophic lateral sclerosis
mlf05022  Pathways of neurodegeneration - multiple diseases
mlf05132  Salmonella infection
mlf05135  Yersinia infection
mlf05145  Toxoplasmosis
mlf05161  Hepatitis B
mlf05163  Human cytomegalovirus infection
mlf05167  Kaposi sarcoma-associated herpesvirus infection
mlf05169  Epstein-Barr virus infection
mlf05170  Human immunodeficiency virus 1 infection
mlf05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mlf05417  Lipid and atherosclerosis
mlf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    102426303 (MAP2K6)
   04668 TNF signaling pathway
    102426303 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102426303 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    102426303 (MAP2K6)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    102426303 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102426303 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102426303 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102426303 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102426303 (MAP2K6)
   05161 Hepatitis B
    102426303 (MAP2K6)
   05163 Human cytomegalovirus infection
    102426303 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102426303 (MAP2K6)
   05169 Epstein-Barr virus infection
    102426303 (MAP2K6)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    102426303 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102426303 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    102426303 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    102426303 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102426303 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    102426303 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102426303 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mlf01001]
    102426303 (MAP2K6)
Enzymes [BR:mlf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     102426303 (MAP2K6)
Protein kinases [BR:mlf01001]
 Serine/threonine kinases: STE group
  STE7 family
   102426303 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 102426303
NCBI-ProteinID: XP_006094984
Ensembl: ENSMLUG00000006692
UniProt: G1P7K5
Position
Unknown
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKLIIGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaatcctggcctcaaaattcccaaagaagcattt
gaacagccccagaccagttccacgccgcctcgagatttagactccaaagcttgcatttct
atcggaaaccagaactttgaggtgaaggcagatgacctggagcctatcatggagctgggc
cgaggtgcgtacggagtggtggagaagatgagacatgtgcccagcgggcagatcatggca
gtgaagcggatccgggccactgtgaacagccaggagcagaaaaggctactgatggacctg
gatgtctccatgaggacggtggactgtccctttacggtcaccttttacggcgcgctcttc
cgggagggtgatgtttggatctgcatggagctcatggatacgtcgctagataaattctac
aaacaagtgattgataaaggccaaaccattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcattagagcatttgcacagtaagctctctgtcatccatcgagacgtc
aagccttccaacgtgctcatcaatgctctgggccaagtgaagatgtgcgactttggcatc
agtggctaccttgtggactcggtggctaaaactatcgatgcaggatgcaaaccgtacatg
gctccggaaaggataaacccggagctcaaccagaagggctacagtgtgaagtctgacatt
tggagtctgggcatcaccatgattgagttggccatccttcggtttccctacgattcatgg
ggaactcctttccagcagctcaaacaggtggtggaggagccgtcaccacagctgcccgca
gacaagttctccgaagagtttgtcgactttacctcgcagtgcttgaagaagaattccaaa
gaacggccaacgtatccagagcttatgcaacatccgtttttcactctacatgaatccaaa
gcaacagacgtggcatcttttgtaaaattgattattggagactaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (24)   
   KEGG PATHWAY (24)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (9)   
   UniProt (1)   
   RefSeq(pep) (8)   
DNA sequence (8)   
   RefSeq(nuc) (8)   
Protein domain (10)   
   Pfam (10)   
All databases (60)   

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