| Entry |
|
|---|
| Name |
Profenamine (INN) |
|---|
| Formula |
C19H24N2S
|
|---|
| Exact mass |
312.1660
|
|---|
| Mol weight |
312.47
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist |
|---|
| Comment |
Phenothiazine derivative
centrally active anticholinergic drugs
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07029 | Antipsychotics - phenothiazines |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N04 ANTI-PARKINSON DRUGS
N04A ANTICHOLINERGIC AGENTS
N04AA Tertiary amines
N04AA05 Profenamine
D08426 Profenamine (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00855 Profenamine
D08426 Profenamine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D08426 Profenamine (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00855 Profenamine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 22
1 C8x C 20.5100 -19.3200
2 C8x C 20.5100 -20.7200
3 C8x C 21.7700 -21.4200
4 C8y C 22.9600 -20.7200
5 C8y C 22.9600 -19.3200
6 C8x C 21.7700 -18.6200
7 S2x S 24.1500 -21.4200
8 C8y C 25.4100 -20.7200
9 C8y C 25.4100 -19.3200
10 N4y N 24.1500 -18.6200
11 C8x C 26.6000 -21.4200
12 C8x C 27.7900 -20.7200
13 C8x C 27.7900 -19.3200
14 C8x C 26.6000 -18.6200
15 C1b C 24.1500 -17.2200
16 C1c C 25.4100 -16.5200
17 C1a C 26.6000 -17.2200
18 N1c N 25.4100 -15.1200
19 C1b C 26.6000 -14.4200
20 C1b C 24.1500 -14.4200
21 C1a C 22.9600 -15.1200
22 C1a C 27.7900 -15.1200
BOND 24
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 2
10 9 10 1
11 5 10 1
12 8 11 1
13 11 12 2
14 12 13 1
15 13 14 2
16 9 14 1
17 10 15 1
18 15 16 1
19 16 17 1
20 16 18 1
21 18 19 1
22 18 20 1
23 20 21 1
24 19 22 1
|
|---|