| Entry |
|
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| Name |
Mebeverine (INN);
Arluy (TN) |
|---|
| Formula |
C25H35NO5
|
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| Exact mass |
429.2515
|
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| Mol weight |
429.55
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antispasmodic, Smooth muscle relaxant, Muscarinic acetylcholine receptor antagonist |
|---|
| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03AA Synthetic anticholinergics, esters with tertiary amino group
A03AA04 Mebeverine
D08160 Mebeverine (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00030 Mebeverine
D08160 Mebeverine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D08160 Mebeverine (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00030 Mebeverine
|
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| Other DBs |
|
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| KCF data |
ATOM 31
1 C8y C 17.9057 -20.0728
2 C8y C 17.9057 -18.6741
3 C8x C 19.0946 -17.9748
4 C8y C 20.3534 -18.6741
5 C8x C 20.3534 -20.0728
6 C8x C 19.0946 -20.7722
7 O2a O 16.7167 -20.7722
8 C1a C 15.4579 -20.0728
9 C1a C 15.4579 -18.6741
10 O2a O 16.7167 -17.9748
11 C7a C 21.5423 -17.9748
12 O7a O 22.7313 -18.6741
13 O6a O 21.5423 -16.5760
14 C1b C 23.9202 -17.9748
15 C1b C 25.1091 -18.6741
16 C1b C 26.2980 -17.9748
17 C1b C 27.4869 -18.6741
18 N1c N 28.6758 -17.9748
19 C1c C 29.9347 -18.6741
20 C1b C 31.1236 -18.0447
21 C1a C 29.9347 -20.1428
22 C1b C 28.6758 -16.5760
23 C1a C 29.9347 -15.8767
24 C8y C 32.3125 -18.7441
25 C8x C 32.3125 -20.1428
26 C8x C 33.5014 -20.8421
27 C8y C 34.6903 -20.1428
28 C8x C 34.6903 -18.7441
29 C8x C 33.5014 -18.0447
30 O2a O 35.9492 -20.8421
31 C1a C 37.1381 -20.1428
BOND 32
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 7 8 1
9 9 10 1
10 2 10 1
11 4 11 1
12 11 12 1
13 11 13 2
14 12 14 1
15 14 15 1
16 15 16 1
17 16 17 1
18 17 18 1
19 18 19 1
20 19 20 1
21 19 21 1
22 18 22 1
23 22 23 1
24 20 24 1
25 24 25 2
26 25 26 1
27 26 27 2
28 27 28 1
29 28 29 2
30 24 29 1
31 27 30 1
32 30 31 1
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