| Entry |
|
|---|
| Name |
Abacavir (INN) |
|---|
| Formula |
C14H18N6O
|
|---|
| Exact mass |
286.1542
|
|---|
| Mol weight |
286.33
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antiviral
DG01890 Nucleoside reverse transcriptase inhibitor (NRTI)
DG03107 Anti-HIV agent
DG01656 HIV reverse transcriptase inhibitor
|
|---|
| Remark |
| Product (DG00660): | D00891<JP/US> |
| Product (mixture): | D10838<US> |
|
|---|
| Efficacy |
Antiviral, Reverse transcriptase inhibitor |
|---|
| Target |
HIV-1 reverse transcriptase [KO: K24802] |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J05 ANTIVIRALS FOR SYSTEMIC USE
J05A DIRECT ACTING ANTIVIRALS
J05AF Nucleoside and nucleotide reverse transcriptase inhibitors
J05AF06 Abacavir
D07057 Abacavir (INN)
Drug groups [BR:br08330]
Antiviral
DG01890 Nucleoside reverse transcriptase inhibitor (NRTI)
DG00660 Abacavir
D07057 Abacavir
DG03107 Anti-HIV agent
DG01656 HIV reverse transcriptase inhibitor
DG00660 Abacavir
D07057 Abacavir
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
HIV reverse transcriptase inhibitor
D07057 Abacavir (INN)
Drug groups [BR:br08330]
Antiviral
DG01890 Nucleoside reverse transcriptase inhibitor (NRTI)
DG00660 Abacavir
DG03107 Anti-HIV agent
DG01656 HIV reverse transcriptase inhibitor
DG00660 Abacavir
Antimicrobials abbreviations [BR:br08327]
Antivirals
Genome replication inhibitor
HIV reverse transcriptase inhibitor
DG00660 Abacavir
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 21
1 C8y C 23.8170 -14.6900
2 C8y C 23.7804 -16.2205
3 C8y C 25.0169 -14.0352
4 N5x N 22.6209 -14.2394
5 N4y N 22.5468 -16.6128
6 N5x N 24.9874 -16.9825
7 N1b N 24.9742 -12.6601
8 N5x N 26.2927 -14.8134
9 C8x C 21.7300 -15.3835
10 C1y C 21.3918 -17.5530
11 C8y C 26.3325 -16.2972
12 C1y C 26.2749 -11.9849
13 C1x C 20.2274 -16.7385
14 C2x C 21.0014 -18.8162
15 N1a N 27.4571 -17.0274
16 C1x C 27.6665 -12.0101
17 C1x C 26.9828 -10.7806
18 C1y C 19.1513 -17.5594
19 C2x C 19.6159 -18.8564
20 C1b C 17.8359 -17.1879
21 O1a O 16.7496 -18.0561
BOND 24
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 2
8 4 9 2
9 10 5 1 #Up
10 6 11 2
11 7 12 1
12 10 13 1
13 10 14 1
14 11 15 1
15 12 16 1
16 12 17 1
17 13 18 1
18 14 19 2
19 18 20 1 #Up
20 20 21 1
21 5 9 1
22 8 11 1
23 16 17 1
24 18 19 1
|
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