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KEGG   ORTHOLOGY: K24802
Entry
K24802                      KO                                     
Symbol
RT
Name
HIV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.13]
Pathway
map03230  Viral genome structure
map03240  Viral replication
map03250  Viral life cycle - HIV-1
map03260  Virion - Human immunodeficiency virus
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03230 Viral genome structure
    K24802  RT; HIV-1 reverse transcriptase / ribonuclease H
   03240 Viral replication
    K24802  RT; HIV-1 reverse transcriptase / ribonuclease H
   03250 Viral life cycle - HIV-1
    K24802  RT; HIV-1 reverse transcriptase / ribonuclease H
   03260 Virion - Human immunodeficiency virus
    K24802  RT; HIV-1 reverse transcriptase / ribonuclease H
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K24802  RT; HIV-1 reverse transcriptase / ribonuclease H
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     K24802  RT; HIV-1 reverse transcriptase / ribonuclease H
    2.7.7.49  RNA-directed DNA polymerase
     K24802  RT; HIV-1 reverse transcriptase / ribonuclease H
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.26  Endoribonucleases producing 5'-phosphomonoesters
    3.1.26.13  retroviral ribonuclease H
     K24802  RT; HIV-1 reverse transcriptase / ribonuclease H
Viral proteins [BR:ko03200]
 ssRNA-RT viruses
  Human immunodeficiency virus
   K24802  RT; HIV-1 reverse transcriptase / ribonuclease H
Other DBs
GO: 0003964 0003887
Genes
VP: 155348-3(p66)
Reference
PMID:19022262
  Authors
Sarafianos SG, Marchand B, Das K, Himmel DM, Parniak MA, Hughes SH, Arnold E
  Title
Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition.
  Journal
J Mol Biol 385:693-713 (2009)
DOI:10.1016/j.jmb.2008.10.071
  Sequence
[vp:155348-3]

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (8)   
   KEGG PATHWAY (8)   
Drug (63)   
   KEGG DRUG (63)   
Chemical reaction (3)   
   KEGG ENZYME (3)   
Gene (1)   
   KEGG GENES (1)   
All databases (78)   

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