| Entry |
|
|---|
| Name |
Hyoscyamine hydrobromide (USP) |
|---|
| Formula |
C17H23NO3. HBr
|
|---|
| Exact mass |
369.0940
|
|---|
| Mol weight |
370.28
|
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| Structure |
|
|---|
| Simcomp |
|
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| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antispasmodic, Muscarinic acetylcholine receptor antagonist |
|---|
| Comment |
Tropane derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03B BELLADONNA AND DERIVATIVES, PLAIN
A03BA Belladonna alkaloids, tertiary amines
A03BA03 Hyoscyamine
D04479 Hyoscyamine hydrobromide (USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00053 Hyoscyamine
D04479 Hyoscyamine hydrobromide
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D04479 Hyoscyamine hydrobromide (USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00053 Hyoscyamine
|
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| Other DBs |
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| KCF data |
ATOM 22
1 C1x C 20.5572 -18.9601
2 C1x C 20.8747 -17.7725
3 C1y C 21.7506 -18.6484
4 C1y C 22.0622 -17.4551
5 N1y N 20.8218 -16.1559
6 C1x C 23.6201 -18.6542
7 C1x C 23.3614 -17.4609
8 C1a C 20.7695 -14.7862
9 C1y C 24.6429 -19.2010
10 O7a O 25.6951 -20.1239
11 C7a C 26.9238 -20.1181
12 C1c C 27.5293 -19.0482
13 O6a O 27.5116 -21.1939
14 C8y C 28.7697 -19.0422
15 C1b C 26.9120 -17.9841
16 C8x C 29.3868 -20.1122
17 C8x C 29.3752 -17.9723
18 O1a O 27.5234 -16.9143
19 C8x C 30.6214 -20.1064
20 C8x C 30.6037 -17.9665
21 C8x C 31.2269 -19.0364
22 X Br 34.0900 -19.1100
BOND 23
1 1 2 1
2 1 3 1
3 2 4 1
4 3 5 1
5 3 6 1
6 4 7 1
7 5 8 1
8 6 9 1
9 9 10 1 #Down
10 10 11 1
11 11 12 1
12 11 13 2
13 12 14 1
14 12 15 1 #Down
15 14 16 2
16 14 17 1
17 15 18 1
18 16 19 1
19 17 20 2
20 19 21 2
21 4 5 1
22 7 9 1
23 20 21 1
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