| Entry |
|
|---|
| Name |
Profenamine hibenzate (JAN);
Parkin (TN) |
|---|
| Formula |
C19H24N2S. C14H10O4
|
|---|
| Exact mass |
554.2239
|
|---|
| Mol weight |
554.70
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist |
|---|
| Comment |
Phenothiazine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07029 | Antipsychotics - phenothiazines |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N04 ANTI-PARKINSON DRUGS
N04A ANTICHOLINERGIC AGENTS
N04AA Tertiary amines
N04AA05 Profenamine
D03276 Profenamine hibenzate (JAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00855 Profenamine
D03276 Profenamine hibenzate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D03276 Profenamine hibenzate (JAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00855 Profenamine
|
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| Other DBs |
|
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| KCF data |
ATOM 40
1 C8y C 4.2000 -19.3900
2 C8y C 4.2000 -20.7900
3 S2x S 5.3900 -21.4900
4 C8y C 6.6500 -20.7900
5 C8y C 6.6500 -19.3900
6 N1y N 5.3900 -18.6900
7 C8x C 7.8400 -21.4900
8 C8x C 9.0300 -20.7900
9 C8x C 9.0300 -19.3900
10 C8x C 7.8400 -18.6900
11 C8x C 3.0100 -18.6900
12 C8x C 1.7500 -19.3900
13 C8x C 1.7500 -20.7900
14 C8x C 3.0100 -21.4900
15 C1b C 5.3900 -17.2900
16 C1c C 6.6500 -16.5900
17 N1c N 6.6500 -15.1900
18 C1b C 7.8400 -14.4900
19 C1a C 8.9600 -15.1900
20 C1a C 7.8400 -17.2900
21 C1b C 5.4600 -14.4900
22 C1a C 4.2700 -15.1900
23 C8x C 14.2100 -19.3200
24 C8x C 14.2100 -20.7200
25 C8x C 15.4700 -21.4200
26 C8x C 16.6600 -20.7200
27 C8y C 16.6600 -19.3200
28 C8y C 15.4700 -18.6200
29 C5a C 17.8500 -18.6200
30 C8y C 19.1100 -19.3200
31 C8x C 19.1100 -20.7200
32 C8x C 20.3000 -21.4200
33 C8y C 21.4900 -20.7200
34 C8x C 21.4900 -19.3200
35 C8x C 20.3000 -18.6200
36 C6a C 15.4700 -17.2200
37 O6a O 16.6600 -16.5200
38 O6a O 14.2100 -16.5200
39 O5a O 17.8500 -17.2200
40 O1a O 22.7053 -21.4151
BOND 43
1 1 2 2
2 2 3 1
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 1
7 4 7 1
8 7 8 2
9 8 9 1
10 9 10 2
11 5 10 1
12 1 11 1
13 11 12 2
14 12 13 1
15 13 14 2
16 2 14 1
17 6 15 1
18 15 16 1
19 16 17 1
20 17 18 1
21 18 19 1
22 16 20 1
23 17 21 1
24 21 22 1
25 29 39 2
26 29 30 1
27 23 24 2
28 24 25 1
29 25 26 2
30 26 27 1
31 27 28 2
32 30 31 2
33 31 32 1
34 32 33 2
35 33 34 1
36 34 35 2
37 35 30 1
38 28 23 1
39 28 36 1
40 36 37 1
41 27 29 1
42 36 38 2
43 33 40 1
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