| Entry |
|
|---|
| Name |
Ipratropium bromide (USP);
Ipratropium bromide hydrate (JP18);
Atrovent (TN) |
|---|
| Product |
|
|---|
| Generic |
IPRATROPIUM BROMIDE (A-S Medication Solutions), IPRATROPIUM BROMIDE (A-S Medication Solutions), IPRATROPIUM BROMIDE (A-S Medication Solutions), IPRATROPIUM BROMIDE (Advagen Pharma), IPRATROPIUM BROMIDE (American Health Packaging), IPRATROPIUM BROMIDE (Amneal Pharmaceuticals NY LLC), IPRATROPIUM BROMIDE (Amneal Pharmaceuticals NY LLC), IPRATROPIUM BROMIDE (Apotex Corp.), IPRATROPIUM BROMIDE (Apotex Corp.), IPRATROPIUM BROMIDE (Aurobindo Pharma Limited), IPRATROPIUM BROMIDE (Bausch & Lomb Incorporated), IPRATROPIUM BROMIDE (Bausch & Lomb Incorporated), IPRATROPIUM BROMIDE (Bryant Ranch Prepack), IPRATROPIUM BROMIDE (Bryant Ranch Prepack), IPRATROPIUM BROMIDE (Cardinal Health 107), IPRATROPIUM BROMIDE (Chartwell RX), IPRATROPIUM BROMIDE (Hikma Pharmaceuticals USA), IPRATROPIUM BROMIDE (Hikma Pharmaceuticals USA), IPRATROPIUM BROMIDE (Mylan Pharmaceuticals), IPRATROPIUM BROMIDE (NORTHSTAR RX LLC), IPRATROPIUM BROMIDE (NORTHSTAR RX LLC), IPRATROPIUM BROMIDE (Nephron Pharmaceuticals Corporation), IPRATROPIUM BROMIDE (Proficient Rx LP), IPRATROPIUM BROMIDE (RPK Pharmaceuticals), IPRATROPIUM BROMIDE (Ritedose Pharmaceuticals), IPRATROPIUM BROMIDE (Sun Pharmaceutical Industries) |
|---|
| Formula |
C20H30NO3. Br. H2O
|
|---|
| Exact mass |
429.1515
|
|---|
| Mol weight |
430.38
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
|
|---|
| Remark |
| Therapeutic category: | 2259 |
| Product (mixture): | D10256<US> |
|
|---|
| Efficacy |
Bronchodilator, Muscarinic acetylcholine receptor antagonist |
|---|
| Disease |
Chronic obstructive pulmonary disease [DS: H01714] Emphysema [DS: H01714] |
|---|
| Comment |
Tropane derivative, Quaternary ammonium compound
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AX Other nasal preparations
R01AX03 Ipratropium bromide
D02212 Ipratropium bromide (USP) <JP/US>
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
R03BB Anticholinergics
R03BB01 Ipratropium bromide
D02212 Ipratropium bromide (USP) <JP/US>
USP drug classification [BR:br08302]
Respiratory Tract/Pulmonary Agents
Bronchodilators, Anticholinergic
Ipratropium
D02212 Ipratropium bromide (USP)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
22 Respiratory organ agents
225 Bronchodilators
2259 Others
D02212 Ipratropium bromide (USP); Ipratropium bromide hydrate (JP18)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
D02212 Ipratropium bromide
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D02212 Ipratropium bromide (USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D02212 Ipratropium bromide hydrate
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 26
1 O0 O 36.0414 -15.4183
2 C1x C 21.9338 -15.2408
3 C1x C 22.2619 -14.0691
4 C1y C 23.1055 -14.9596
5 C1y C 23.4336 -13.7879
6 N2y N 22.1682 -12.4756 #+
7 C1x C 24.9802 -14.9596
8 C1x C 24.6990 -13.7879
9 C1y C 26.0113 -15.5220
10 O7a O 27.0893 -16.4125
11 C7a C 28.3079 -16.4125
12 C1c C 28.9172 -15.3345
13 O6a O 28.9172 -17.5373
14 C8y C 30.1358 -15.3345
15 C1b C 28.3079 -14.3034
16 O1a O 28.9172 -13.2255
17 C8x C 30.8420 -16.5582
18 C8x C 32.2420 -16.5585
19 C8x C 32.9422 -15.3462
20 C8x C 32.2361 -14.1225
21 C8x C 30.8361 -14.1222
22 C1a C 21.4191 -11.2914
23 C1c C 20.9389 -13.0883
24 C1a C 19.7662 -12.3118
25 C1a C 20.9231 -14.4879
26 X Br 25.9700 -11.4800 #-
BOND 26
1 2 3 1
2 2 4 1
3 3 5 1
4 4 6 1
5 4 7 1
6 5 8 1
7 7 9 1
8 9 10 1 #Down
9 10 11 1
10 11 12 1
11 11 13 2
12 12 14 1
13 12 15 1
14 15 16 1
15 5 6 1
16 8 9 1
17 14 17 2
18 17 18 1
19 18 19 2
20 19 20 1
21 20 21 2
22 14 21 1
23 6 22 1
24 6 23 1
25 23 24 1
26 23 25 1
|
|---|