| Entry |
|
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| Name |
Pirenzepine hydrochloride (USAN) |
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| Formula |
C19H21N5O2. 2HCl
|
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| Exact mass |
423.1229
|
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| Mol weight |
424.32
|
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| Structure |
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| Simcomp |
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| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
Gastrointestinal agent
DG01975 Agents for peptic ulcer
|
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| Remark |
| Product (DG00026): | D05276<JP> |
|
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| Efficacy |
Antisecretory (gastric acid), Anti-ulcerative, Muscarinic acetylcholine receptor antagonist |
|---|
| Comment |
Tricyclic compound
|
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
|
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| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A02 DRUGS FOR ACID RELATED DISORDERS
A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
A02BX Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)
A02BX03 Pirenzepine
D01297 Pirenzepine hydrochloride (USAN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Pirenzepine
D01297 Pirenzepine hydrochloride (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00026 Pirenzepine
D01297 Pirenzepine hydrochloride
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG00026 Pirenzepine
D01297 Pirenzepine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D01297 Pirenzepine hydrochloride (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00026 Pirenzepine
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG00026 Pirenzepine
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| Other DBs |
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| KCF data |
ATOM 28
1 X Cl 36.4585 -18.1487
2 C5x C 29.0500 -23.2400
3 C8y C 28.2100 -22.1200
4 C8y C 28.5600 -20.7900
5 N1y N 29.8200 -20.2300
6 N1x N 30.4500 -23.2400
7 C8y C 31.0800 -20.8600
8 C8y C 31.3600 -22.1900
9 C8x C 27.5100 -19.8100
10 C8x C 26.1800 -20.2300
11 C8x C 25.8300 -21.5600
12 C8x C 26.8800 -22.5400
13 C8x C 32.6900 -22.6100
14 C8x C 33.7400 -21.7000
15 C8x C 33.4600 -20.3000
16 N5x N 32.1300 -19.8800
17 O5x O 28.4200 -24.5000
18 C5a C 29.8200 -18.8300
19 C1b C 31.0100 -18.1300
20 O5a O 28.6300 -18.1300
21 N1y N 31.0100 -16.7300
22 C1x C 32.2700 -16.0300
23 C1x C 32.2700 -14.6300
24 N1y N 31.0100 -13.9300
25 C1x C 29.8200 -14.6300
26 C1x C 29.8200 -16.0300
27 C1a C 31.0100 -12.5300
28 X Cl 36.4585 -18.1487
BOND 29
1 4 5 1
2 2 6 1
3 5 7 1
4 3 4 1
5 6 8 1
6 2 3 1
7 7 8 1
8 4 9 2
9 9 10 1
10 10 11 2
11 11 12 1
12 3 12 2
13 8 13 2
14 13 14 1
15 14 15 2
16 15 16 1
17 7 16 2
18 2 17 2
19 5 18 1
20 18 19 1
21 18 20 2
22 19 21 1
23 21 22 1
24 22 23 1
25 23 24 1
26 24 25 1
27 25 26 1
28 21 26 1
29 24 27 1
BRACKET 1 34.7900 -19.1800 34.7900 -17.0100
1 37.3100 -17.0100 37.3100 -19.1800
1 2
ORIGINAL 1 1
REPEAT 1 28
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