| Entry |
|
|---|
| Name |
Methyclothiazide (JAN/USP/INN);
Enduron (TN) |
|---|
| Formula |
C9H11Cl2N3O4S2
|
|---|
| Exact mass |
358.9568
|
|---|
| Mol weight |
360.24
|
|---|
| Structure |
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| Simcomp |
|
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| Class |
|
|---|
| Remark |
|
|---|
| Efficacy |
Antihypertensive, Diuretic, Na+-Cl- symport inhibitor |
|---|
| Disease |
|
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| Comment |
Thiazides
|
|---|
| Target |
|
|---|
| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C03 DIURETICS
C03A LOW-CEILING DIURETICS, THIAZIDES
C03AA Thiazides, plain
C03AA08 Methyclothiazide
D00656 Methyclothiazide (JAN/USP/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG01749 Thiazide diuretic
D00656 Methyclothiazide
DG01690 Sulfonamide diuretic
DG01749 Thiazide diuretic
D00656 Methyclothiazide
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC12
SLC12A1 (NKCC2)
D00656 Methyclothiazide (JAN/USP/INN)
SLC12A3 (TSC)
D00656 Methyclothiazide (JAN/USP/INN)
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| Other DBs |
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| KCF data |
ATOM 20
1 C8y C 25.7021 -20.2574
2 C8y C 25.7079 -18.8595
3 N1x N 24.5022 -20.9563
4 C8x C 26.9135 -20.9622
5 C8x C 26.9252 -18.1606
6 S2x S 24.5022 -18.1548
7 C1y C 23.2849 -20.2574
8 C8y C 28.1308 -20.2690
9 C8y C 28.1367 -18.8654
10 N1y N 23.2849 -18.8595
11 O3c O 23.4947 -17.1531
12 O3c O 25.7021 -17.4500
13 C1b C 22.0735 -20.9563
14 X Cl 29.3307 -20.9622
15 S4a S 29.3365 -18.1665
16 C1a C 22.0678 -18.1548
17 X Cl 20.8621 -20.2574
18 N1a N 30.5479 -17.4616
19 O3c O 28.6448 -16.9792
20 O3c O 30.0541 -19.3982
BOND 21
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 4 8 2
8 5 9 2
9 6 10 1
10 6 11 2
11 6 12 2
12 7 13 1
13 8 14 1
14 9 15 1
15 10 16 1
16 13 17 1
17 15 18 1
18 7 10 1
19 8 9 1
20 15 19 2
21 15 20 2
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