| Entry |
|
|---|
| Name |
Hydroflumethiazide (JAN/USP/INN);
Saluron (TN) |
|---|
| Formula |
C8H8F3N3O4S2
|
|---|
| Exact mass |
330.9908
|
|---|
| Mol weight |
331.30
|
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| Structure |
|
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| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
|
|---|
| Efficacy |
Antihypertensive, Diuretic, Na+-Cl- symport inhibitor |
|---|
| Comment |
Thiazides
|
|---|
| Target |
|
|---|
| Interaction |
|
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| Structure map |
| map07017 | Sulfonamide derivatives - diuretics |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C03 DIURETICS
C03A LOW-CEILING DIURETICS, THIAZIDES
C03AA Thiazides, plain
C03AA02 Hydroflumethiazide
D00654 Hydroflumethiazide (JAN/USP/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG01749 Thiazide diuretic
D00654 Hydroflumethiazide
DG01690 Sulfonamide diuretic
DG01749 Thiazide diuretic
D00654 Hydroflumethiazide
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC12
SLC12A1 (NKCC2)
D00654 Hydroflumethiazide (JAN/USP/INN)
SLC12A3 (TSC)
D00654 Hydroflumethiazide (JAN/USP/INN)
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| Other DBs |
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| KCF data |
ATOM 20
1 C8y C 22.4065 -16.5814
2 C8y C 22.4123 -15.1825
3 C8x C 23.6122 -17.2897
4 N1x N 21.2006 -17.2838
5 C8x C 23.6239 -14.4860
6 S2x S 21.2006 -14.4801
7 C8y C 24.8296 -16.5931
8 C1x C 19.9832 -16.5814
9 C8y C 24.8356 -15.1942
10 N1x N 19.9832 -15.1825
11 O3c O 20.1881 -13.4850
12 O3c O 22.4065 -13.7777
13 C1d C 26.0355 -17.2897
14 S4a S 26.0413 -14.4801
15 X F 27.2354 -16.5814
16 X F 26.0238 -18.6886
17 X F 27.2354 -17.9921
18 N1a N 27.2472 -13.7777
19 O3c O 27.2472 -15.1825
20 O3c O 25.0405 -13.4850
BOND 21
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 1
8 5 9 2
9 6 10 1
10 6 11 2
11 6 12 2
12 7 13 1
13 9 14 1
14 13 15 1
15 13 16 1
16 13 17 1
17 14 18 1
18 14 19 2
19 14 20 2
20 7 9 1
21 8 10 1
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