KEGG NETWORK: N00361

NETWORK: N00361

Entry

N00361                      Network

Name

HPV E7 to cell cycle G1/S

Definition

E7 -> (RB1,RBL1,RBL2) // E2F

Expanded

K21809 -> (5925,5933,5934) // (1869,1870,1871)

Class

nt06166 Human papillomavirus (HPV)

Type

Pathogen

Pathway

hsa05165

Human papillomavirus infection

Disease

H00030

Cervical cancer

Gene

5925	RB1; RB transcriptional corepressor 1

5933	RBL1; RB transcriptional corepressor like 1

5934	RBL2; RB transcriptional corepressor like 2

1869	E2F1; E2F transcription factor 1

1870	E2F2; E2F transcription factor 2

1871	E2F3; E2F transcription factor 3

Perturbant

K21809 (E7)

E7; HPV protein E7

Reference

PMID:12044013

Authors

Boshoff C, Weiss R

Title

AIDS-related malignancies.

Journal

Nat Rev Cancer 2:373-82 (2002)
DOI:10.1038/nrc797

Reference

PMID:19684440

Authors

Lehoux M, D'Abramo CM, Archambault J

Title

Molecular mechanisms of human papillomavirus-induced carcinogenesis.

Journal

Public Health Genomics 12:268-80 (2009)
DOI:10.1159/000214918

Reference

PMID:20592731

Authors

Moody CA, Laimins LA

Title

Human papillomavirus oncoproteins: pathways to transformation.

Journal

Nat Rev Cancer 10:550-60 (2010)
DOI:10.1038/nrc2886

Reference

PMID:24388872

Authors

de Freitas AC, Coimbra EC, Leitao Mda C

Title

Molecular targets of HPV oncoproteins: potential biomarkers for cervical carcinogenesis.

Journal

Biochim Biophys Acta 1845:91-103 (2014)
DOI:10.1016/j.bbcan.2013.12.004

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (6)   
Literature (4)   
   PubMed (4)   
All databases (12)   

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