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KEGG    Network variation - HIF signaling
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ENTRYnt06542
NameHIF signaling
CategoryPathway view; Signal transduction
Pathwayhsa04066 HIF-1 signaling pathway
DiseaseH00021 Renal cell carcinoma
H00559 von Hippel-Lindau syndrome
Display drug-target relation   disease type
N00079        HIF1A=ARNT(SLC2A1,VEGFA,TGFB..
     D1
 |
    
N01870        EPAS1=ARNT(VEGFA,CXCL8,GLUT1..
    ECYT4     EPAS1*
    ECYT5         EPO*
 D1
 |
   D1
 |
N01871    (HIF1A,EPAS1)EGLN(HIF1A-OH,EPAS1-OH..
    ECYT3   EGLN1*
     D1
 |
N01872      (VHL+RBX1+ELOC+ELO..(HIF1A-OH,EPAS1-OH..
N00080    RCC   (VHL*+RBX1+ELOC+EL..HIF1A=ARNT(SLC2A1,VEGFA,TGFB..
N00081    RCC   (VHL*+RBX1+ELOC+EL..HIF1A=ARNT(SLC2A1,VEGFA,TGFB..
     D1
 |
    
N01873    RCC/VHLS/ECYT2   (VHL*+RBX1+ELOC+EL..EPAS1=ARNT(VEGFA,CXCL8,GLUT1..

Disease nameDisease category
ECYT4H00236Congenital polycythemiaHematologic disease
ECYT5H00236Congenital polycythemiaHematologic disease
ECYT3H00236Congenital polycythemiaHematologic disease
RCCH00021Renal cell carcinomaCancer
RCC/VHLS/ECYT2H00021Renal cell carcinomaCancer
H00559von Hippel-Lindau syndromeCongenital malformation
H00236Congenital polycythemiaHematologic disease


Drug name
D1D11954Belzutifan (JAN/USAN/INN)