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Online ISSN: 1945-4589
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The cover features Figure 7 "Effect of age and CR on the fecal metabolome“ from Kurup et al.

Volume 13, Issue 5

15 March, 2021
pp 6231—7708

About the Cover

The cover features Figure 7 "Effect of age and CR on the fecal metabolome“ from Kurup et al.

Explore This Issue

Editorials

Metabolomics, heart disease and aging

Michela Piedepalumbo, Walter J. Koch, Claudio de Lucia,
https://doi.org/10.18632/aging.202804 pp 6231—6232
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Flux control in the aging cascade

Bernd Moosmann,
https://doi.org/10.18632/aging.202821 pp 6233—6235
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Research Papers

COVID-19
Elevated frequencies of CD14+HLA-DRlo/neg MDSCs in COVID-19 patients

GuoHui Xue, Mei Jiang, Rui Zhao, AiPing Le, JunMing Li,
https://doi.org/10.18632/aging.202571 pp 6236—6246
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COVID-19
Centenarians in nursing homes during the COVID-19 pandemic

Anne-Laure Couderc, Florian Correard, Emilie Nouguerède, Julie Berbis, Dominique Rey, Aurélie Daumas, Patrick Villani,
https://doi.org/10.18632/aging.202743 pp 6247—6257
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COVID-19
Screening potential FDA-approved inhibitors of the SARS-CoV-2 major protease 3CLpro through high-throughput virtual screening and molecular dynamics simulation

Wen-Shan Liu, Han-Gao Li, Chuan-Hua Ding, Hai-Xia Zhang, Rui-Rui Wang, Jia-Qiu Li,
https://doi.org/10.18632/aging.202703 pp 6258—6272
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COVID-19
The networks of m6A-SARS-CoV-2 related genes and immune infiltration patterns in idiopathic pulmonary fibrosis

Xinyu Li, Cheng Peng, Ziqing Zhu, Haozheng Cai, Quan Zhuang,
https://doi.org/10.18632/aging.202725 pp 6273—6288
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COVID-19
Clinical characteristics and peripheral immunocyte subsets alteration of 85 COVID-19 deaths

Liangkun Xiong, Xin Zang, Guohe Feng, Fangfang Zhao, Shihong Wang, Wenhui Zeng, Kaihuan Yu, Yongzhen Zhai,
https://doi.org/10.18632/aging.202819 pp 6289—6297
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Calorie restriction prevents age-related changes in the intestinal microbiota

Kavitha Kurup, Stephanie Matyi, Cory B. Giles, Jonathan D. Wren, Kenneth Jones, Aaron Ericsson, Daniel Raftery, Lu Wang, Daniel Promislow, Arlan Richardson, Archana Unnikrishnan,
https://doi.org/10.18632/aging.202753 pp 6298—6329
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Age-dependent remodeling of gut microbiome and host serum metabolome in mice

Chia-Shan Wu, Sai Deepak Venkata Muthyala, Cory Klemashevich, Arinzechukwu Uchenna Ufondu, Rani Menon, Zheng Chen, Sridevi Devaraj, Arul Jayaraman, Yuxiang Sun,
https://doi.org/10.18632/aging.202525 pp 6330—6345
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In vitro P38MAPK inhibition in aged astrocytes decreases reactive astrocytes, inflammation and increases nutritive capacity after oxygen-glucose deprivation

Miren Revuelta, Amaia Elicegui, Till Scheuer, Stefanie Endesfelder, Christoph Bührer, Leire Moreno-Cugnon, Ander Matheu, Thomas Schmitz,
https://doi.org/10.18632/aging.202651 pp 6346—6358
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Mucosal microRNAs relate to age and severity of disease in ulcerative colitis

Mikkel Malham, Jaslin P. James, Christian Jakobsen, Estrid Hoegdall, Kim Holmstroem, Vibeke Wewer, Boye S. Nielsen, Lene B. Riis,
https://doi.org/10.18632/aging.202715 pp 6359—6374
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Oral administration of Akkermansia muciniphila elevates systemic antiaging and anticancer metabolites

Claudia Grajeda-Iglesias, Sylvère Durand, Romain Daillère, Kristina Iribarren, Fabien Lemaitre, Lisa Derosa, Fanny Aprahamian, Noélie Bossut, Nitharsshini Nirmalathasan, Frank Madeo, Laurence Zitvogel, Guido Kroemer,
https://doi.org/10.18632/aging.202739 pp 6375—6405
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Ablation of CRBN induces loss of type I collagen and SCH in mouse skin by fibroblast senescence via the p38 MAPK pathway

Seungje Jeon, Yi-Seul Yoon, Hyoung Kyu Kim, Jin Han, Kwang Min Lee, Jung Eun Seol, Steve K. Cho, Chul-Seung Park,
https://doi.org/10.18632/aging.202744 pp 6406—6419
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Aging and pathological aging signatures of the brain: through the focusing lens of SIRT6

Daniel Stein, Amir Mizrahi, Anastasia Golova, Adam Saretzky, Alfredo Garcia Venzor, Zeev Slobodnik, Shai Kaluski, Monica Einav, Ekaterina Khrameeva, Debra Toiber,
https://doi.org/10.18632/aging.202755 pp 6420—6441
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Male-specific age estimation based on Y-chromosomal DNA methylation

Athina Vidaki, Diego Montiel González, Benjamin Planterose Jiménez, Manfred Kayser,
https://doi.org/10.18632/aging.202775 pp 6442—6458
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Development of the VISAGE enhanced tool and statistical models for epigenetic age estimation in blood, buccal cells and bones

Anna Woźniak, Antonia Heidegger, Danuta Piniewska-Róg, Ewelina Pośpiech, Catarina Xavier, Aleksandra Pisarek, Ewa Kartasińska, Michał Boroń, Ana Freire-Aradas, Marta Wojtas, Maria de la Puente, Harald Niederstätter, Rafał Płoski, Magdalena Spólnicka, Manfred Kayser, Christopher Phillips, Walther Parson, Wojciech Branicki, VISAGE Consortium,
https://doi.org/10.18632/aging.202783 pp 6459—6484
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Clusterin overexpression in mice exacerbates diabetic phenotypes but suppresses tumor progression in a mouse melanoma model

Christina Cheimonidi, Ioannis N. Grivas, Fabiola Sesti, Nadia Kavrochorianou, Despoina D. Gianniou, Era Taoufik, Fotis Badounas, Issidora Papassideri, Federica Rizzi, Ourania E. Tsitsilonis, Sylva Haralambous, Ioannis P. Trougakos,
https://doi.org/10.18632/aging.202788 pp 6485—6505
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Impact of genetic variants on clinical outcome after percutaneous coronary intervention in elderly patients

Jung-Joon Cha, Jae Hyoung Park, Hyung Joon Joo, Soon Jun Hong, Tae Hoon Ahn, Byeong-Keuk Kim, WonYong Shin, Sung Gyun Ahn, JungHan Yoon, Yong Hoon Kim, Yun-Hyeong Cho, Woong Chol Kang, Weon Kim, Young-Hyo Lim, Hyeon Cheol Gwon, Woong Gil Choi, Do-Sun Lim,
https://doi.org/10.18632/aging.202799 pp 6506—6524
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Hypoxia associated multi-omics molecular landscape of tumor tissue in patients with hepatocellular carcinoma

Qiangnu Zhang, Lijun Qiao, Quan Liu, Xiangpan Kong, Jun Hu, Weibin Hu, Zongze Wu, Mingyue Li, Liping Liu,
https://doi.org/10.18632/aging.202723 pp 6525—6553
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A prognostic model for melanoma patients on the basis of immune-related lncRNAs

Yao Wang, Hong-Jun Ba, Xi-Zhi Wen, Min Zhou, Can Küçük, Luca Tamagnone, Li Wei, Hua You,
https://doi.org/10.18632/aging.202730 pp 6554—6564
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Phenotyping of immune and endometrial epithelial cells in endometrial carcinomas revealed by single-cell RNA sequencing

Yu-e Guo, Yiran Li, Bailian Cai, Qizhi He, Guofang Chen, Mengfei Wang, Kai Wang, Xiaoping Wan, Qin Yan,
https://doi.org/10.18632/aging.202288 pp 6565—6591
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Lupeol ameliorates LPS/D-GalN induced acute hepatic damage by suppressing inflammation and oxidative stress through TGFβ1-Nrf2 signal pathway

Sha Huang, Chan Mo, Ting Zeng, Yuqi Lai, Chuying Zhou, Shunwen Xie, Limei Chen, Yuhua Wang, Yuyao Chen, Shaohui Huang, Lei Gao, Zhiping Lv,
https://doi.org/10.18632/aging.202409 pp 6592—6605
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Coexpression of HOXA6 and PBX2 promotes metastasis in gastric cancer

Jianjiao Lin, Huiqiong Zhu, Linjie Hong, Weimei Tang, Jing Wang, Hongsong Hu, Xiaosheng Wu, Yaying Chen, Guangnan Liu, Qiong Yang, Jiaying Li, Yusi Wang, Zhizhao Lin, Yizhi Xiao, Weiyu Dai, Miaojvan Huang, Guoxin Li, Aimin Li, Jide Wang, Li Xiang, Side Liu,
https://doi.org/10.18632/aging.202426 pp 6606—6624
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Liraglutide preconditioning attenuates myocardial ischemia/ reperfusion injury via homer1 activation

Xiangrong Cui, Hongping Liang, Chonghua Hao, Xuan Jing,
https://doi.org/10.18632/aging.202429 pp 6625—6633
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CRISPR/Cas9-mediated CysLT1R deletion reverses synaptic failure, amyloidosis and cognitive impairment in APP/PS1 mice

Fang Chen, Shunchang Fang, Yifeng Du, Arijit Ghosh, Miranda N. Reed, Yan Long, Vishnu Suppiramaniam, Susu Tang, Hao Hong,
https://doi.org/10.18632/aging.202501 pp 6634—6661
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The novel roles of virus infection-associated gene CDKN1A in chemoresistance and immune infiltration of glioblastoma

Kuan Hu, Juanni Li, Geting Wu, Lei Zhou, Xiang Wang, Yuanliang Yan, Zhijie Xu,
https://doi.org/10.18632/aging.202519 pp 6662—6680
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Indoxyl sulfate caused behavioral abnormality and neurodegeneration in mice with unilateral nephrectomy

Chiao-Yin Sun, Jian-Ri Li, Ya-Yu Wang, Shih-Yi Lin, Yen-Chuan Ou, Cheng-Jui Lin, Jiaan-Der Wang, Su-Lan Liao, Chun-Jung Chen,
https://doi.org/10.18632/aging.202523 pp 6681—6701
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The impact of visceral obesity on chronic constipation, inflammation, immune function and cognitive function in patients with inflammatory bowel disease

Yemin Wan, Dan Zhang, Ting Xing, Qiaoling Liu, Yumeng Chi, Huixiang Zhang, Haihua Qian,
https://doi.org/10.18632/aging.202526 pp 6702—6711
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CPI-1189 protects neuronal cells from oxygen glucose deprivation/re-oxygenation-induced oxidative injury and cell death

Yong-Jun Li, Yueli Zhan, Chengrui Li, Jianhong Sun, Chengliang Yang,
https://doi.org/10.18632/aging.202528 pp 6712—6723
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MiR-506 exerts antineoplastic effects on osteosarcoma cells via inhibition of the Skp2 oncoprotein

Lu Ding, Rongxin Sun, Qi Yan, Chengwei Wang, Xiaoping Han, Yong Cui, Rong Li, Jiwen Liu,
https://doi.org/10.18632/aging.202530 pp 6724—6739
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Interleukin-33 modulates immune responses in cutaneous melanoma in a context-specific way

Liang Peng, Wei Sun, Fanqin Wei, Lin Chen, Weiping Wen,
https://doi.org/10.18632/aging.202531 pp 6740—6751
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Extracellular vesicle-encapsulated microRNA-23a from dorsal root ganglia neurons binds to A20 and promotes inflammatory macrophage polarization following peripheral nerve injury

Yamei Zhang, Junying Liu, Xin Wang, Jinfeng Zhang, Chenchen Xie,
https://doi.org/10.18632/aging.202532 pp 6752—6764
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Growth hormone ameliorates the age-associated depletion of ovarian reserve and decline of oocyte quality via inhibiting the activation of Fos and Jun signaling

Chuanming Liu, Shiyuan Li, Yifan Li, Jiao Tian, Xiaoling Sun, Tianran Song, Guijun Yan, Lijun Ding, Haixiang Sun,
https://doi.org/10.18632/aging.202534 pp 6765—6781
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The role of CDX2 in renal tubular lesions during diabetic kidney disease

Huiming Liu, Rui Yan, Luqun Liang, Huifang Zhang, Jiayi Xiang, Lingling Liu, Xiaohuan Zhang, Yanwen Mao, Wei Peng, Ying Xiao, Fan Zhang, Yuxia Zhou, Mingjun Shi, Yuanyuan Wang, Bing Guo,
https://doi.org/10.18632/aging.202537 pp 6782—6803
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Transcription factor ELK1 accelerates aerobic glycolysis to enhance osteosarcoma chemoresistance through miR-134/PTBP1 signaling cascade

Qiang Zhang, Jiaqi Wu, Xiangfeng Zhang, Le Cao, Yongping Wu, Xudong Miao,
https://doi.org/10.18632/aging.202538 pp 6804—6819
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Nicardipine sensitizes temozolomide by inhibiting autophagy and promoting cell apoptosis in glioma stem cells

Jia Shi, Xuchen Dong, Haoran Li, Haiyang Wang, Qianqian Jiang, Liang Liu, Liping Wang, Jun Dong,
https://doi.org/10.18632/aging.202539 pp 6820—6831
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LncRNA TRPM2-AS promotes ovarian cancer progression and cisplatin resistance by sponging miR-138-5p to release SDC3 mRNA

Yi Ding, Xiangyu Tan, Abuduyilimu Abasi, Yun Dai, Ruxing Wu, Tao Zhang, Kexin Li, Miao Yan, Xiaoyuan Huang,
https://doi.org/10.18632/aging.202541 pp 6832—6848
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Association of HIF1-α gene polymorphisms with advanced non-small cell lung cancer prognosis in patients receiving radiation therapy

Yan Zhang, Jian Wang, Zhanzhan Li,
https://doi.org/10.18632/aging.202542 pp 6849—6865
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Association between body mass index and risk of cardiovascular disease-specific mortality among adults with hypertension in Shanghai, China

Jing Hu, Huilin Xu, Jingjing Zhu, Jinling Zhang, Jun Li, Linli Chen, Xiaohua Liu, Guoyou Qin,
https://doi.org/10.18632/aging.202543 pp 6866—6877
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Resveratrol improves Gly-LDL-induced vascular endothelial cell apoptosis, inflammatory factor secretion and oxidative stress by regulating miR-142-3p and regulating SPRED2-mediated autophagy

Wenjun Sha, Meizhi Liu, Dusang Sun, Junhui Qiu, Bilin Xu, Lin Chen, Tian Shen, Cheng Chen, Hongping Wang, Cuiping Zhang, Tao Lei,
https://doi.org/10.18632/aging.202546 pp 6878—6889
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MET inhibitor, capmatinib overcomes osimertinib resistance via suppression of MET/Akt/snail signaling in non-small cell lung cancer and decreased generation of cancer-associated fibroblasts

Kaibin Zhu, Zhonghua Lv, Jinsheng Xiong, Hongshan Zheng, Sibin Zhang, Hua Jin, Lei Yu, Zhenzhe Li, Jixing Zhang, Chenlong Li, Peng Liang,
https://doi.org/10.18632/aging.202547 pp 6890—6903
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The effects of aging on the renal function of a healthy population in Beijing and an evaluation of a range of estimation equations for glomerular filtration rate

Xu Lengnan, Chen Aiqun, Sun Ying, Li Chuanbao, Mao Yonghui,
https://doi.org/10.18632/aging.202548 pp 6904—6917
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LncRNA Sirt1-AS upregulates Sirt1 to attenuate aging related deep venous thrombosis

Zhenkai Lou, Jinwen Zhu, Xing Li, Xingguo Li, Kaili Du, Bing Wang, Fan Zhang, Xinliang Zhang,
https://doi.org/10.18632/aging.202550 pp 6918—6935
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Hypofractionated versus conventionally fractionated image-guided volumetric-modulated arc radiotherapy for localized prostate cancer: a phase II randomized trial from China

Qiu-Zi Zhong, Xiu Xia, Hong Gao, Yong-Gang Xu, Ting Zhao, Qin-Hong Wu, Dan Wang, Hai-Lei Lin, Xiang-Yan Sha, Ming Liu, Gao-Feng Li,
https://doi.org/10.18632/aging.202551 pp 6936—6944
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Silencing of miR-483-5p alleviates postmenopausal osteoporosis by targeting SATB2 and PI3K/AKT pathway

Fujiang Zhao, Yier Xu, Yulong Ouyang, Zhexu Wen, Guihao Zheng, Ting Wan, Guicai Sun,
https://doi.org/10.18632/aging.202552 pp 6945—6956
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Identification of a ten-long noncoding RNA signature for predicting the survival and immune status of patients with bladder urothelial carcinoma based on the GEO database: a superior machine learning model

XuDong Mao, ShiHan Chen, GongHui Li,
https://doi.org/10.18632/aging.202553 pp 6957—6981
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Discovery of a novel AR/HDAC6 dual inhibitor for prostate cancer treatment

Maojun Zhou, Hao Zheng, Yubin Li, Huichao Huang, Xiaoli Min, Shuyan Dai, Wenqiang Zhou, Zhuchu Chen, Guangyu Xu, Yongheng Chen,
https://doi.org/10.18632/aging.202554 pp 6982—6998
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Integrative analysis of genomic, epigenomic and transcriptomic data identified molecular subtypes of esophageal carcinoma

Mingyang Ma, Yang Chen, Xiaoyi Chong, Fangli Jiang, Jing Gao, Lin Shen, Cheng Zhang,
https://doi.org/10.18632/aging.202556 pp 6999—7019
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The efficiency and safety of high-dose vitamin C in patients with COVID-19: a retrospective cohort study

Dengfeng Gao, Min Xu, Gang Wang, Jianrui Lv, Xiaorong Ma, Yonghong Guo, Dexin Zhang, Huiyun Yang, Wei Jiang, Fuxue Deng, Guozhi Xia, Ziwei Lu, Lv Lv, Shouping Gong,
https://doi.org/10.18632/aging.202557 pp 7020—7034
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ENAM gene associated with T classification and inhibits proliferation in renal clear cell carcinoma

Xiaohan Ren, Shengjie Liang, Yang Li, Yisheng Ji, Lin Li, Chao Qin, Kai Fang,
https://doi.org/10.18632/aging.202558 pp 7035—7051
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Infertility network and hub genes for nonobstructive azoospermia utilizing integrative analysis

Baoquan Han, Zihui Yan, Shuai Yu, Wei Ge, Yaqi Li, Yan Wang, Bo Yang, Wei Shen, Hui Jiang, Zhongyi Sun,
https://doi.org/10.18632/aging.202559 pp 7052—7066
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GIT1 protects traumatically injured spinal cord by prompting microvascular endothelial cells to clear myelin debris

Bowen Wan, Cong Li, Ming Wang, Fanqi Kong, Qirui Ding, Chenliang Zhang, Hao Liu, Dingfei Qian, Wenlin Deng, Jian Chen, Pengyu Tang, Qian Wang, Shujie Zhao, Zheng Zhou, Tao Xu, Yifan Huang, Jun Gu, Jin Fan, Guoyong Yin,
https://doi.org/10.18632/aging.202560 pp 7067—7083
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Paeoniflorin attenuates DHEA-induced polycystic ovary syndrome via inactivation of TGF-β1/Smads signaling pathway in vivo

Jie Zhou, Yong Tan, Xudong Wang, Meihong Zhu,
https://doi.org/10.18632/aging.202564 pp 7084—7095
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Berberine-induced TFEB deacetylation by SIRT1 promotes autophagy in peritoneal macrophages

Yinghong Zheng, Jiayuan Kou, Pengyu Wang, Ting Ye, Zitong Wang, Ziyu Gao, Lin Cong, Manman Li, Bowen Dong, Wei Yang, Quanfeng Li, Hong Li, Rui Wang, Liming Yang,
https://doi.org/10.18632/aging.202566 pp 7096—7119
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Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway

Wenpeng Cao, Zhirui Zeng, Zhiwei He, Shan Lei,
https://doi.org/10.18632/aging.202569 pp 7120—7132
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Clinical features and prognostic factors of elderly patients with metastatic pancreatic cancer: a population-based study

Tao Lianyuan, Li Deyu, Yu Haibo, Dong Yadong, Tian Guanjing,
https://doi.org/10.18632/aging.202570 pp 7133—7146
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No difference in hepatocellular carcinoma risk in chronic hepatitis B patients treated with tenofovir vs entecavir: evidence from an updated meta-analysis

Jie Yuan, Yang Peng, Fa-Bao Hao, Ya-Qin Wang, Chun-Rui Wang, Guo-Chao Zhong,
https://doi.org/10.18632/aging.202573 pp 7147—7165
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Raddeanin A inhibits proliferation, invasion, migration and promotes apoptosis of cervical cancer cells via regulating miR-224-3p/Slit2/Robo1 signaling pathway

Xin Shen, Lingxia Li, Yuanyuan He, Xiaohui Lv, Jiajia Ma,
https://doi.org/10.18632/aging.202574 pp 7166—7179
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Neuroprotective effect of hydrogen sulfide against glutamate-induced oxidative stress is mediated via the p53/glutaminase 2 pathway after traumatic brain injury

Jianping Sun, Xiaoyu Li, Xiaoyu Gu, Hailong Du, Gengshen Zhang, Jianliang Wu, Feng Wang,
https://doi.org/10.18632/aging.202575 pp 7180—7189
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Frailty is an independent risk factor of one-year mortality after elective orthopedic surgery: a prospective cohort study

Xiaoyun Sun, Yuying Shen, Muhuo Ji, Shanwu Feng, Yuzhu Gao, Jianjun Yang, Jinchun Shen,
https://doi.org/10.18632/aging.202576 pp 7190—7198
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APDL1-CART cells exhibit strong PD-L1-specific activity against leukemia cells

Qunyi Peng, Xiongpeng Zhu, Chuntuan Li, Pengliang Xin, Yan Zheng, Shengquan Liu,
https://doi.org/10.18632/aging.202578 pp 7199—7210
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Follistatin-like 1 deficiency impairs T cell development to promote lung metastasis of triple negative breast cancer

Jie Ma, Ying Yang, Lulu Wang, Xiaowei Jia, Tao Lu, Yiyan Zeng, Li Liu, Yan Gao,
https://doi.org/10.18632/aging.202579 pp 7211—7227
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Evaluating the association between brain atrophy, hypometabolism, and cognitive decline in Alzheimer’s disease: a PET/MRI study

Yifan Chen, Junkai Wang, Chunlei Cui, Yusheng Su, Donglai Jing, LiYong Wu, Peipeng Liang, Zhigang Liang,
https://doi.org/10.18632/aging.202580 pp 7228—7246
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Impact of adiposity on muscle function and clinical events among elders with dynapenia, presarcopenia and sarcopenia: a community-based cross-sectional study

Tung-Wei Kao, Tao-Chun Peng, Wei-Liang Chen, Der-Sheng Han, Chi-Ling Chen, Wei-Shiung Yang,
https://doi.org/10.18632/aging.202581 pp 7247—7258
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Pan-cancer investigation reveals mechanistic insights of planar cell polarity gene Fuz in carcinogenesis

Zhefan Stephen Chen, Xiao Lin, Ting-Fung Chan, Ho Yin Edwin Chan,
https://doi.org/10.18632/aging.202582 pp 7259—7283
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Prognostic value of glycolysis markers in head and neck squamous cell carcinoma: a meta-analysis

Yanting Wang, Yuanyuan Li, Laibo Jiang, Xianyue Ren, Bin Cheng, Juan Xia,
https://doi.org/10.18632/aging.202583 pp 7284—7299
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Maf1 suppression of ATF5-dependent mitochondrial unfolded protein response contributes to rapamycin-induced radio-sensitivity in lung cancer cell line A549

Chen Lai, Jing Zhang, Zhaohua Tan, Liang F. Shen, Rong R. Zhou, Ying Y. Zhang,
https://doi.org/10.18632/aging.202584 pp 7300—7313
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Levodopa affects spike and local field synchronisation in the pedunculopontine nucleus of a rat model of Parkinson’s disease

Hao Zhang, Jinlu Xie, Yaqiong Li, Huimin Liu, Chuanguo Liu, Dongfang Kan, Xiwen Geng, Sheng Wei,
https://doi.org/10.18632/aging.202585 pp 7314—7329
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The aging-related risk signature in colorectal cancer

Taohua Yue, Shanwen Chen, Jing Zhu, Shihao Guo, Zhihao Huang, Pengyuan Wang, Shuai Zuo, Yucun Liu,
https://doi.org/10.18632/aging.202589 pp 7330—7349
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Association of metabolic syndrome with the incidence of low-grade albuminuria: a cohort study in middle-aged and elderly Chinese adults

Meng Ren, Lili You, Diaozhu Lin, Qiling Feng, Chulin Huang, Feng Li, Yiqin Qi, Wanting Feng, Chuan Yang, Li Yan, Kan Sun,
https://doi.org/10.18632/aging.202592 pp 7350—7360
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Artificial intelligence prediction model for overall survival of clear cell renal cell carcinoma based on a 21-gene molecular prognostic score system

Qiliang Peng, Yi Shen, Kai Fu, Zheng Dai, Lu Jin, Dongrong Yang, Jin Zhu,
https://doi.org/10.18632/aging.202594 pp 7361—7381
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Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma

Wen Tian, He Yang, Baosen Zhou,
https://doi.org/10.18632/aging.202596 pp 7382—7396
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Prognostic significance of epigenetic regulatory gene expression in patients with non-small-cell lung cancer

Zegui Tu, Xiancheng Chen, Tian Tian, Guo Chen, Meijuan Huang,
https://doi.org/10.18632/aging.202600 pp 7397—7415
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A bioinformatic analysis: the overexpression and clinical significance of FCGBP in ovarian cancer

Kai Wang, Chenan Guan, Xianwen Shang, Xiang Ying, Shuangshuang Mei, Hanxiao Zhu, Liang Xia, Zeying Chai,
https://doi.org/10.18632/aging.202601 pp 7416—7429
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Potential role of glucosamine-phosphate N-acetyltransferase 1 in the development of lung adenocarcinoma

Shengqiang Zhang, Hongyan Zhang, Huawei Li, Jida Guo, Jun Wang, Linyou Zhang,
https://doi.org/10.18632/aging.202604 pp 7430—7453
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The serum galectin-3 levels are associated with the severity and prognosis of ischemic stroke

Jia-Jun Zhuang, Li Zhou, Yan-Hua Zheng, Yan-Sheng Ding,
https://doi.org/10.18632/aging.202610 pp 7454—7464
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SNPs within microRNA binding sites and the prognosis of breast cancer

Liwen Zhang, Lu Han, Yubei Huang, Ziwei Feng, Xin Wang, Haixin Li, Fangfang Song, Luyang Liu, Junxian Li, Hong Zheng, Peishan Wang, Fengju Song, Kexin Chen,
https://doi.org/10.18632/aging.202612 pp 7465—7480
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Identification and validation of a glycolysis-associated multiomics prognostic model for hepatocellular carcinoma

Tuo Deng, Qian Ye, Chen Jin, Mingliang Wu, Kaiyu Chen, Jinhuan Yang, Ziyan Chen, XiXiang Yu, Gang Chen, Yi Wang,
https://doi.org/10.18632/aging.202613 pp 7481—7498
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BDKRB2 is a novel EMT-related biomarker and predicts poor survival in glioma

Ying Yang, Jin Wang, Fei Shi, Aijun Shan, Shihai Xu, Wen Lv,
https://doi.org/10.18632/aging.202614 pp 7499—7516
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Molecular characterization of long-term survivors of hepatocellular carcinoma

Junwei Shen, Jing Hu, Jiawen Wu, Xiaoli Luo, Yanfei Li, Jue Li,
https://doi.org/10.18632/aging.202615 pp 7517—7537
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SEDT2/METTL14-mediated m6A methylation awakening contributes to hypoxia-induced pulmonary arterial hypertension in mice

Xue-Liang Zhou, Feng-Jian Huang, Yang Li, Huang Huang, Qi-Cai Wu,
https://doi.org/10.18632/aging.202616 pp 7538—7548
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Preclinical systematic review of ginsenoside Rg1 for cognitive impairment in Alzheimer’s disease

Hai-Yong Liang, Pei-Pei Zhang, Xi-Le Zhang, Yan-Yan Zheng, Yan-Ran Huang, Guo-Qing Zheng, Yan Lin,
https://doi.org/10.18632/aging.202619 pp 7549—7569
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Low expression of NLRP1 is associated with a poor prognosis and immune infiltration in lung adenocarcinoma patients

Edward Shen, Ying Han, Changjing Cai, Ping Liu, Yihong Chen, Le Gao, Qiaoqiao Huang, Hong Shen, Shan Zeng, Min He,
https://doi.org/10.18632/aging.202620 pp 7570—7588
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Fecal microbiota transplantation mitigates vaginal atrophy in ovariectomized mice

Jia Huang, Wanying Shan, Fuxia Li, Zizhuo Wang, Jing Cheng, Funian Lu, Ensong Guo, Rajluxmee Beejadhursing, Rourou Xiao, Chen Liu, Bin Yang, Xi Li, Yu Fu, Ling Xi, Shixuan Wang, Ding Ma, Gang Chen, Chaoyang Sun,
https://doi.org/10.18632/aging.202627 pp 7589—7607
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MiR-452-5p promotes colorectal cancer progression by regulating an ERK/MAPK positive feedback loop

Xin Lin, Lu Han, Chuncai Gu, Yihong Lai, Qiuhua Lai, Qingyuan Li, Chengcheng He, Yan Meng, Lei Pan, Side Liu, Aimin Li,
https://doi.org/10.18632/aging.202657 pp 7608—7626
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Nicotine exacerbates atherosclerosis through a macrophage-mediated endothelial injury pathway

ChengYu Mao, DongJiu Li, En Zhou, JunFeng Zhang, ChangQian Wang, Chao Xue,
https://doi.org/10.18632/aging.202660 pp 7627—7643
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Platelets transport β-amyloid from the peripheral blood into the brain by destroying the blood-brain barrier to accelerate the process of Alzheimer's disease in mouse models

Tong Wu, Lizhi Chen, Lingqi Zhou, Jie Xu, Kaihua Guo,
https://doi.org/10.18632/aging.202662 pp 7644—7659
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Long noncoding RNA NR2F1-AS1 promotes the malignancy of non-small cell lung cancer via sponging microRNA-493-5p and thereby increasing ITGB1 expression

Chan Zhang, Shangjie Wu, Rong Song, Changming Liu,
https://doi.org/10.18632/aging.103564 pp 7660—7675
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Downregulation of microRNA-29b by DNMT3B decelerates chondrocyte apoptosis and the progression of osteoarthritis via PTHLH/CDK4/RUNX2 axis

Pengcheng Dou, Yu He, Bo Yu, Juan Duan,
https://doi.org/10.18632/aging.103778 pp 7676—7690
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Review

β cell aging and age-related diabetes

Min Zhu, Xiaohong Liu, Wen Liu, Yanrong Lu, Jingqiu Cheng, Younan Chen,
https://doi.org/10.18632/aging.202593 pp 7691—7706
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Corrections

Correction for: Signatures of cell stress and altered bioenergetics in skin fibroblasts from patients with multiple sclerosis

Jordan M. Wilkins, Oleksandr Gakh, Parijat Kabiraj, Christina B. McCarthy, W. Oliver Tobin, Charles L. Howe, Claudia F. Lucchinetti,
https://doi.org/10.18632/aging.202757 pp 7707
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Correction for: Development and validation of a RNA binding protein-associated prognostic model for lung adenocarcinoma

Wei Li, Li-Na Gao, Pei-Pei Song, Chong-Ge You,
https://doi.org/10.18632/aging.202826 pp 7708
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