85 posts tagged with genes.
Displaying 1 through 50 of 85. Subscribe:
Cocoon
Old mice grow young again in study. Can people do the same? - "In Boston labs, old, blind mice have regained their eyesight, developed smarter, younger brains and built healthier muscle and kidney tissue. On the flip side, young mice have prematurely aged, with devastating results to nearly every tissue in their bodies." [more inside]
Cells, is there anything they can't do?
@SCOTTeHENSLEY: "We developed a new multivalent mRNA vaccine against all known influenza virus subtypes. Our study describing the vaccine was just published..." [more inside]
splice/never let me go: I can't wait to see you lace your shoes*
1st synthetic mouse embryos — complete with beating hearts and brains — created with no sperm, eggs or womb - "For the first time, scientists have created mouse embryos in the lab without using any eggs or sperm and watched them grow outside the womb. To achieve this feat, the researchers used only stem cells and a spinning device filled with shiny glass vials." [more inside]
Retron Library Recombineering
Scientists Have Created A New Gene-Editing Tool That Could Outperform CRISPR - "It is faster and simpler than CRISPR, enabling millions of genetic experiments to be performed simultaneously." [more inside]
minimal cells
Scientists Create Simple Synthetic Cell That Grows and Divides Normally - "New findings shed light on mechanisms controlling the most basic processes of life."[1] [more inside]
More Fun Than Fun: How Do Insect Societies Deal With Infectious Diseases
...Colonies of social insects such as those of ants, bees, wasps and termites present parasites with a paradise of sorts: they contain densely packed individuals that are also rather genetically similar and hence of similar susceptibility. Not surprisingly, parasites are the scourge of insect societies. But insect societies have not only survived this scourge but are among the most evolutionarily successful and ecologically dominant members of Earth’s terrestrial fauna.More Fun Than Fun: How Do Insect Societies Deal With Infectious Diseases?
Skyscrapers for plants: maybe farm/forest arcologies should be things
Wheat yield potential in controlled-environment vertical farms - "Here we show that wheat grown on a single hectare of land in a 10-layer indoor vertical facility could produce ... 220 to 600 times the current world average annual wheat yield of 3.2 t/ha." (via) [more inside]
We’re all “mutants”.
The Lazy Design Aesthetic of Misrepresenting Genetic Conditions [Plenty of Minds]
“In books, films and video games, “mutant” is often used interchangeably with various terms that essentially mean “other”: “freak,” “monster,” “beast,” et cetera. However, it isn’t completely interchangeable because everyone understands that “mutant” has something to do with genetics and biological development. Therefore, the choice to use the term “mutant” implies that there is some biological, likely genetic, basis for why these “monsters” are the way they are. [...] It appears to me that the designers were just cribbing dysmorphic features that occur in real life and applying them to the game’s monsters, then naming them “mutants” and going on their way. Why do they look the way they are? Because they’re “mutants.” No additional thought went into that.”Michael California draws upon his background as a geneticist to compliment a discussion of Rage 2‘s industry-standard ableism with an explanation of why the “mutant” tropes of disfigurement and disability widely perpetuated in popular media make no scientific sense whatsoever. [YouTube][Rage 2 Launch Trailer] [more inside]
Higher Steaks
Will 2019 be the year of lab-grown meat? - "After years in the lab, will meats derived from animal cells finally break into the mainstream consumer market? The products could have huge implications for the planet, human health and animal welfare." [more inside]
Nexus 0.1
Chinese scientists are creating CRISPR babies - "A daring effort is under way to create the first children whose DNA has been tailored using gene editing." [more inside]
"I think it's hard for people to come to terms with their own mortality"
Timothy Caulfield is the Canada Research Chair in Health Law and Policy, Professor & Research Director at the University of Alberta. He is also fascinated by pseudoscientific celebrity health advice, specifically how it's based on bad science, and on that topic, published the book Is Gwyneth Paltrow Wrong About Everything? (Goodreads). He also uses his humour, quick wit and science knowledge to investigate trendy diets, ancient therapies, wellness and anti-aging products to separate science fact from fiction in a series called A User’s Guide to Cheating Death (YT, trailer). He's into his second season of six episodes each, streaming for free from Vision TV for folks in Canada, and all 12 episodes are available on Netflix, too. More below the break. [more inside]
Bringing Us One Step Closer to Our Real-Life Themyscira
Same-sex mouse parents give birth via gene editing: Scientists delivered pups with genetic material from two moms and two dads. But only pups with two moms survived to have babies themselves "In an important move for both science as well as Women Who Are Over This Shit, researchers in China have just helped a pair of female mouse parents give birth to healthy pups via gene editing and stem cells, no male mice involved."
The Viruses That Neanderthals Spread to Humans
Deep in Human DNA, a Gift From the Neanderthals. "Long ago, Neanderthals probably infected modern humans with viruses, perhaps even an ancient form of H.I.V. But our extinct relatives also gave us genetic defenses." "The two ancient hominin groups swapped genes, diseases, and genes that protect against diseases, according to a new study."
The Corn of the Future Is Hundreds of Years Old and Makes Its Own Mucus
The Wonder Plant That Could Slash Fertilizer Use - "An indigenous Mexican corn gets its nitrogen from the air."
And the plants and the animals eat each other
Insect farms gear up to feed soaring global protein demand - "Layers of squirming black soldier fly larvae fill large aluminum bins stacked 10-high in a warehouse outside of Vancouver. They are feeding on stale bread, rotting mangoes, overripe cantaloupe and squishy zucchini." [more inside]
When a gene-edited butterfly flaps its wings, evolution evolves
Scientists Can Now Repaint Butterfly Wings - "Thanks to CRISPR, scientists are studying animal evolution in ways that were previously thought to be impossible." [more inside]
No Pain to Infinite Pain
GM Mosquitoes: What Could Go Wrong?
Inside the insectary - "These gene drives, they're able to copy themselves. So instead of half of the offspring inheriting the gene drive, almost all of them do. So what happens is that it spreads and it spreads and it spreads. And this is the fantastic thing. Because it allows that gene to be selfish in a population. And in a very short amount of time you can actually transform an entire wild population into a modified population. It's powerful." (previously: 1,2,3)
Meet Luca, the Ancestor of All Living Things
Genes that do the same thing in a human and a mouse are generally related by common descent from an ancestral gene in the first mammal. So by comparing their sequence of DNA letters, genes can be arranged in evolutionary family trees, a property that enabled Dr. Martin and his colleagues to assign the six million genes to a much smaller number of gene families. Of these, only 355 met their criteria for having probably originated in Luca, the joint ancestor of bacteria and archaea.Meet Luca, the Ancestor of All Living Things [more inside]
The DIY Scientist, the Olympian, and the Mutated Gene
It seemed absolutely crazy. The idea that an Iowa housewife, equipped with the cutting-edge medical tool known as Google Images, would make a medical discovery about a pro athlete who sees doctors and athletic trainers as part of her job? via
Genegineering
Humans 2.0 - "With CRISPR, scientists can change, delete, and replace genes in any animal, including us. Working mostly with mice, researchers have already deployed the tool to correct the genetic errors responsible for sickle-cell anemia, muscular dystrophy, and the fundamental defect associated with cystic fibrosis. One group has replaced a mutation that causes cataracts; another has destroyed receptors that H.I.V. uses to infiltrate our immune system." [more inside]
Most assuredly *not* 42
This is my vision of life. A conversation with evolutionary biologist and author Richard Dawkins. (Video and transcript)
Charging toward an era of genetically modified humans
The CRISPR Revolution [ungated: 1,2,3] - "Biologists continue to hone their tools for deleting, replacing or otherwise editing DNA and a strategy called CRISPR has quickly become one of the most popular ways to do genome engineering. Utilizing a modified bacterial protein and a RNA that guides it to a specific DNA sequence, the CRISPR system provides unprecedented control over genes in many species, including perhaps humans. This control has allowed many new types of experiments, but also raised questions about what CRISPR can enable." [more inside]
Engineering the Perfect Baby
Neanderthal and Sapiens, sitting in a tree...
"Scientists have reconstructed the genome of a man who lived 45,000 years ago, by far the oldest genetic record ever obtained from modern humans. The research, published on Wednesday in the journal Nature, provided new clues to the expansion of modern humans from Africa about 60,000 years ago, when they moved into Europe and Asia.
And the genome, extracted from a fossil thighbone found in Siberia, added strong support to a provocative hypothesis: Early humans interbred with Neanderthals."
An essay on the biology of pregnancy
"The mammal mother works hard to stop her children from taking more than she is willing to give. The children fight back with manipulation, blackmail and violence. Their ferocity is nowhere more evident than in the womb [...] Pregnancy is a lot more like war than we might care to admit."
plant sex in silico
Monsanto Is Going Organic in a Quest for the Perfect Veggie - "The lettuce, peppers, and broccoli—plus a melon and an onion, with a watermelon soon to follow—aren't genetically modified at all. Monsanto created all these veggies using good old-fashioned crossbreeding, the same technology that farmers have been using to optimize crops for millennia. That doesn't mean they are low tech, exactly. Stark's division is drawing on Monsanto's accumulated scientific know-how to create vegetables that have all the advantages of genetically modified organisms without any of the Frankenfoods ick factor." [more inside]
Nice basic guide to the three new-ish tools for rewriting Genes
Zinc-finger-nucleases, TALENs, and CRISPR, oh my! The three tools, especially the last one, CRISPR, make rewriting Genes doable. Now the "fun" begins.
Are you alive? If so, can you define what that means?
PATIENT ZERO
"‘The gene does not lead,’ she says. ‘It follows.’"
Epigenetics in Feast, Famine: How Well Grampa Ate Could Impact Grandkids
Epigenetics (prev) is the study of changes in gene expression or cellular phenotype, caused by mechanisms other than changes in the underlying DNA sequence. David Epstein, a senior writer for Sports Illustrated has written about this topic for his book The Sports Gene (not as reductive as the title might suggest), but cut the chapter because the material he researched was so new as to require that he "caveat the writing rather heavily." Instead, he shared his chapter How an 1836 Famine Altered the Genes of Children Born Decades Later on IO9. You can read or hear more about the book in a half-hour segment from NPR's Fresh Air, opening with a story of Jennie Finch, a softball pitcher who "just whiff[ed] the best hitters in the world." (Related video clip: FSN Sport Science - Episode 7: Myths - Jennie Finch, on the force of fast baseball vs softball; ends with smarmy teaser for a "sex test")
Memes, memes, hedgehogs and sharks.
Richard Dawkins talks about memes. [SLYT, contains flashing images]
All Ur DNA Base R Belong To U
"We hold that a naturally occurring DNA segment is a product of nature and not patent eligible merely because it has been isolated," Justice Clarence Thomas writes in the court's decision following a unanimous ruling in the case of Association for Molecular Pathology et al. v. Myriad Genetics, Inc., et al..
"Myriad did not create or alter either the genetic information encoded in the BCRA1 and
BCRA2 genes or the genetic structure of the DNA. It found an important and useful gene, but groundbreaking, innovative, or even brilliant discovery does not by itself satisfy the §101 inquiry." [more inside]
One genome, two plants
Mosses Make Two Different Plants From the Same Genome, and a Single Gene Can Make the Difference
One of the most astonishing secrets in biology is this: every plant you see makes two different plants from the same genome. And, scientists recently reported, a single gene from an ancient, powerful lineage can make the difference.
Intelligence Tests
Is Psychometric g a Myth? - "As an online discussion about IQ or general intelligence grows longer, the probability of someone linking to statistician Cosma Shalizi's essay g, a Statistical Myth approaches 1. Usually the link is accompanied by an assertion to the effect that Shalizi offers a definitive refutation of the concept of general mental ability, or psychometric g." [more inside]
Make Babies
"Older parenthood will upend American society." "Is waiting to have kids a big mistake?" "Why do women believe they can delay children for so long?" "Older men are more likely than young ones to father a child who develops autism or schizophrenia, because of random mutations that become more numerous with advancing paternal age."
One great step. The first gene linked to autism.
The etiology of Autism remains a mystery. However, three research teams have for the first time linked a gene to certain forms of autism. This is a great step in the search of what causes this disease.
Can you spare 3 minutes a week to become fit?
Just three minutes a week of exercise can help make you fit. That's 180 seconds out of 604,800. 'This apparently outrageous claim is supported by many years of research'. 'A few relatively short bursts of intense exercise, amounting to only a few minutes a week, can deliver many of the health and fitness benefits of hours of conventional exercise, according to new research.''But how much benefit you get from either may well depend on your genes.' [more inside]
Can't fit in the jeans because of the genes.
Couch Potatoes Explained - Missing Key Genes May Be Cause for Lack of Resolve to Exercise, Researchers Find. 'You may think your lack of resolve to get off the couch to exercise is because you're lazy, but McMaster University researchers have discovered it may be you are missing key genes.' 'The research appears in the current issue of the Proceedings of the National Academy of Sciences.' [more inside]
Cat Color Genetics
After decades of breeding, the complexity of cat color genetics is quite well understood. Genes which control pigmentation, hair length, color dilution, banding (agouti), white fur (dominant, spotting, or albino, sometimes linked with deafness), tabby patterns, and more combine to create a wide spectrum of possibilities. Specific traits such as white gloving among Birman cats and the amber color found only in Norwegian Forest Cats (which comes from a single female born in 1981!) have also been isolated and studied, and can be affordably tested for.
On top of all that, fur color is epigenetic as well as genetic, and sometimes responds to the cat's environment. If you clone a calico cat, you get a kitten which doesn't have a similar coat due to X-inactivation, and pointed cats (such as Burmese, Siamese, and Tonkinese) have temperature-sensitive coloration. [more inside]
Collect 'Em All!
This is a game about breeding flowers. Each flower's traits are determined by its genes. Pick two flowers and their genes combine to create new variations. There is no aim in this game... Feel free to set yourself one. -- Rare Breeds: Petunia. (Flash.) [more inside]
Mushroom Sex
"People who use sows to hunt for truffles often find it hard to prevent a sex-crazed animal from eating the truffle she has found and may lose fingers in the attempt." (via) The NYT on decoding the genome of the Périgord Black Truffle . Attempts to make truffles cheaper and more accessible in the past have been met with some resistance.
Y Front Page Post
Indeed, at 6 million years of separation, the difference in [Y-chromosome] gene content in chimpanzee and human is more comparable to the difference in autosomal gene content in chicken and human, at 310 million years of separation.It is commonly said that the Human and Chimpanzee genomes share 99% or more identical DNA. In a surprising development about to be published in Nature, the Y-chromosomes of these two species were found to share only 70% of their DNA, raising important questions about the mode and tempo by which speciation from a common ancestor occurred. This finding may point the finger at the evolution of different patterns of sperm-competition and mating practices within these two species.
(glowing) prairie voles illuminate the human condition
Monogamouse
Prairie voles have many vasopressin receptors in the reward centres of their brains. It seems as though these are wired up in a way that causes the animal to take pleasure from monogamy. (previously 1|2)
Prairie voles have many vasopressin receptors in the reward centres of their brains. It seems as though these are wired up in a way that causes the animal to take pleasure from monogamy. (previously 1|2)
Learn.Genetics
grumblebee's post about cell size and scale the other day was quite fascinating. Pulling back to the home for that site, the Genetic Science Learning Center at the University of Utah delivers educational materials on genetics, bio-science and health topics ranging from stem cells to gene therapy, and from epigenetics to heredity. Explore the neurobiology of normal and addicted brains and the genetic contribution to this chronic disease.
The Third Replicator
The Beauty Race
Researchers have found that beautiful women have more children than their plainer counterparts and that a higher proportion of those children are female. Those daughters, once adult, also tend to be attractive and so repeat the pattern.
The Genomic Self
My Genome, My Self: Steven Pinker considers what we can expect from personal genomics. Searching for Intelligence in Our Genes: Carl Zimmer looks at the hunt to learn about the role of genes in intelligence.
Darwin, extended
The "blind watchmaker" may not be as blind as we thought. A team of scientists at Princeton University discovers that organisms are not only evolving, they're evolving to evolve better, using a set of proteins to "steer the process of evolution toward improved fitness" by making tiny course corrections.
Page:
1 2