Sal N. DiDomenico is an American state legislator who has served in the Massachusetts Senate since May 2010 and as Assistant Majority Leader since 2018. He is a Democrat representing the Middlesex and Suffolk district, which includes his hometown of Everett as well as Chelsea, Allston, Brighton, Charlestown, and parts of Cambridge and Boston. In 2010, he won a special election to succeed the retiring Anthony D. Galluccio. Before that, he spent three years as Gallucio's chief of staff. From 2004 to 2010 he was a member of the Everett City Council.