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RecLOH is a term in genetics that is an abbreviation for "Recombinant Loss of Heterozygosity". This is a type of mutation which occurs with DNA by recombination. From a pair of equivalent ("homologous"), but slightly different (heterozygous) genes, a pair of identical genes results. In this case there is a non-reciprocal exchange of genetic code between the chromosomes, in contrast to chromosomal crossover, because genetic information is lost.