About: DS-1 (drug)

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

DS-1 is a drug from the imidazopyridine family, which is the first drug developed that acts as a GABAA receptor positive allosteric modulator (PAM) selective for the α4β3δ subtype, which is not targeted by other GABAA receptor PAMs such as the benzodiazepines or other nonbenzodiazepine drugs. Novel selective drugs such as DS-1 should prove useful in the study of this receptor subtype.

Property	Value
dbo:abstract	DS-1 is a drug from the imidazopyridine family, which is the first drug developed that acts as a GABAA receptor positive allosteric modulator (PAM) selective for the α4β3δ subtype, which is not targeted by other GABAA receptor PAMs such as the benzodiazepines or other nonbenzodiazepine drugs. Novel selective drugs such as DS-1 should prove useful in the study of this receptor subtype. (en)
dbo:casNumber	372497-52-4
dbo:pubchem	979735
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dbo:wikiPageWikiLink	dbr:Saripidem dbr:Benzodiazepine dbc:Chloroarenes dbc:GABAA_receptor_positive_allosteric_modulators dbc:Organobromides dbr:Zolpidem dbr:Positive_allosteric_modulator dbr:GABAA_receptor dbr:GABRA4 dbr:GABRB3 dbr:GABRD dbr:Alpidem dbc:Benzamides dbc:Imidazopyridines dbr:Nonbenzodiazepine dbc:Thiophenes dbr:Imidazopyridine
dbp:br	2 (xsd:integer)
dbp:c	18 (xsd:integer)
dbp:casNumber	372497 (xsd:integer)
dbp:chemspiderid	849261 (xsd:integer)
dbp:cl	1 (xsd:integer)
dbp:drugName	DS-1 (en)
dbp:h	10 (xsd:integer)
dbp:iupacName	4 (xsd:integer)
dbp:iupharLigand	4183 (xsd:integer)
dbp:n	3 (xsd:integer)
dbp:o	1 (xsd:integer)
dbp:pubchem	979735 (xsd:integer)
dbp:s	1 (xsd:integer)
dbp:smiles	s4cccc4-c2nc1ccccn1c2NCcccc3Cl (en)
dbp:verifiedrevid	451225367 (xsd:integer)
dbp:wikiPageUsesTemplate	dbt:Drugbox dbt:GABAAR_PAMs dbt:Reflist dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Sedative-stub
dct:subject	dbc:Chloroarenes dbc:GABAA_receptor_positive_allosteric_modulators dbc:Organobromides dbc:Benzamides dbc:Imidazopyridines dbc:Thiophenes
gold:hypernym	dbr:Drug
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug umbel-rc:DrugProduct
rdfs:comment	DS-1 is a drug from the imidazopyridine family, which is the first drug developed that acts as a GABAA receptor positive allosteric modulator (PAM) selective for the α4β3δ subtype, which is not targeted by other GABAA receptor PAMs such as the benzodiazepines or other nonbenzodiazepine drugs. Novel selective drugs such as DS-1 should prove useful in the study of this receptor subtype. (en)
rdfs:label	DS-1 (drug) (en)
owl:sameAs	freebase:DS-1 (drug) wikidata:DS-1 (drug) dbpedia-sh:DS-1 (drug) dbpedia-sr:DS-1 (drug) https://global.dbpedia.org/id/4iYrj
prov:wasDerivedFrom	wikipedia-en:DS-1_(drug)?oldid=963838745&ns=0
foaf:depiction	wiki-commons:Special:FilePath/DS-1.svg
foaf:isPrimaryTopicOf	wikipedia-en:DS-1_(drug)
foaf:name	DS-1 (en)
is dbo:wikiPageWikiLink of	dbr:DS1 dbr:Imidazopyridine
is foaf:primaryTopic of	wikipedia-en:DS-1_(drug)