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Conipyridoin E is a derivative produced by the fungus Coniochaeta cephalothecoides which was found on a Tibetan Plateau. This natural product has been shown to exhibit antibacterial and antifungal activity against a variety of bacteria, such as Staphylococcus aureus, methicillin-resistant Staphyloccusaureus, and Enterococcus faecalis with MIC50 values of around 0.97 μM. Isolation of a number of analogs of conipyridoin has been accomplished by Han et al. in order to discover novel antibiotic natural products to combat antibiotic resistance.

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dbo:abstract
  • Conipyridoin E is a derivative produced by the fungus Coniochaeta cephalothecoides which was found on a Tibetan Plateau. This natural product has been shown to exhibit antibacterial and antifungal activity against a variety of bacteria, such as Staphylococcus aureus, methicillin-resistant Staphyloccusaureus, and Enterococcus faecalis with MIC50 values of around 0.97 μM. Isolation of a number of analogs of conipyridoin has been accomplished by Han et al. in order to discover novel antibiotic natural products to combat antibiotic resistance. (en)
dbo:iupacName
  • 3-[(1S,2S,4aR,6S,8aS')-2,6-Dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalene-1-carbonyl]-4-hydroxy-5-[(4-hydroxyphenyl)methylidene]pyrrol-2-one (en)
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  • Conipyridoin e structure.png (en)
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  • Conipyridoin E (en)
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  • Conipyridoin E is a derivative produced by the fungus Coniochaeta cephalothecoides which was found on a Tibetan Plateau. This natural product has been shown to exhibit antibacterial and antifungal activity against a variety of bacteria, such as Staphylococcus aureus, methicillin-resistant Staphyloccusaureus, and Enterococcus faecalis with MIC50 values of around 0.97 μM. Isolation of a number of analogs of conipyridoin has been accomplished by Han et al. in order to discover novel antibiotic natural products to combat antibiotic resistance. (en)
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  • Conipyridoin E (en)
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  • Conipyridoin E (en)
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