[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

About: MYLK4

An Entity of Type: protein, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Myosin light chain kinase 4 also known as MYLK4 is an enzyme which in humans is encoded by the MYLK2 gene. MYLK4 is a member of the myosin light-chain kinase family of serine/threonine-specific protein kinases that phosphorylate the regulatory light chain of myosin II. This protein acts as an enzyme that catalyzes the following reaction: ATP + a protein -> ADP + a phosphoprotein. MYLK4 is also involved in protein amino acid phosphorylation meaning that it adds a phosphate group onto the molecule. There are other known myosin light-chain kinase enzymes.

Property Value
dbo:abstract
  • Myosin light chain kinase 4 also known as MYLK4 is an enzyme which in humans is encoded by the MYLK2 gene. MYLK4 is a member of the myosin light-chain kinase family of serine/threonine-specific protein kinases that phosphorylate the regulatory light chain of myosin II. This protein acts as an enzyme that catalyzes the following reaction: ATP + a protein -> ADP + a phosphoprotein. MYLK4 is also involved in protein amino acid phosphorylation meaning that it adds a phosphate group onto the molecule. Not very much is known about the specific functional characteristics of MLYK4, but it has recently been found that the gene may possibly have a role in having at least one driver mutation for cancer.MYLK4 may also be involved in transferase activity, ATP binding, protein serine/threonine kinase activity, and also nucleotide binding.Other names for MYLK4 are CaMLCK like; EG238564; MYLK4; Mylk4; Myosin light chain kinase family, member 4; SgK085; SGK085; Sgk085; Sugen kinase 85; Uncharacterized serine/threonine-protein kinase SgK085. There are other known myosin light-chain kinase enzymes. (en)
  • MYLK4 (англ. Myosin light chain kinase family member 4) – білок, який кодується однойменним геном, розташованим у людей на 6-й хромосомі. Довжина поліпептидного ланцюга білка становить 388 амінокислот, а молекулярна маса — 44 508. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин Кодований геном білок за функціями належить до трансфераз, кіназ, серин/треонінових протеїнкіназ. Задіяний у такому біологічному процесі, як альтернативний сплайсинг. Білок має сайт для зв'язування з АТФ, нуклеотидами. (uk)
dbo:arm
  • p
dbo:band
  • 25.2
dbo:chromosome
  • 6
dbo:ecNumber
  • 2.7.11.18
dbo:entrezgene
  • 340156
dbo:hgncid
  • 27972
dbo:refseq
  • NM_001012418
dbo:symbol
  • MYLK4
dbo:thumbnail
dbo:uniprot
  • Q86YV6
dbo:wikiPageID
  • 21548428 (xsd:integer)
dbo:wikiPageLength
  • 3786 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1081132645 (xsd:integer)
dbo:wikiPageWikiLink
dbp:arm
  • p (en)
dbp:band
  • 25.200000 (xsd:double)
dbp:caption
  • The crystal structure of the human myosin light chain kinase Loc340156. (en)
dbp:chromosome
  • 6 (xsd:integer)
dbp:ecnumber
  • 2.700000 (xsd:double)
dbp:entrezgene
  • 340156 (xsd:integer)
dbp:hgncid
  • 27972 (xsd:integer)
dbp:name
  • Myosin light chain kinase family, member 4 (en)
dbp:refseq
  • NM_001012418 (en)
dbp:symbol
  • MYLK4 (en)
dbp:uniprot
  • Q86YV6 (en)
dbp:wikiPageUsesTemplate
dct:subject
gold:hypernym
rdf:type
rdfs:comment
  • Myosin light chain kinase 4 also known as MYLK4 is an enzyme which in humans is encoded by the MYLK2 gene. MYLK4 is a member of the myosin light-chain kinase family of serine/threonine-specific protein kinases that phosphorylate the regulatory light chain of myosin II. This protein acts as an enzyme that catalyzes the following reaction: ATP + a protein -> ADP + a phosphoprotein. MYLK4 is also involved in protein amino acid phosphorylation meaning that it adds a phosphate group onto the molecule. There are other known myosin light-chain kinase enzymes. (en)
  • MYLK4 (англ. Myosin light chain kinase family member 4) – білок, який кодується однойменним геном, розташованим у людей на 6-й хромосомі. Довжина поліпептидного ланцюга білка становить 388 амінокислот, а молекулярна маса — 44 508. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин (uk)
rdfs:label
  • MYLK4 (en)
  • MYLK4 (uk)
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
foaf:name
  • Myosin light chain kinase family, member 4 (en)
is dbo:wikiPageWikiLink of
is dbp:symbol of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License