INSRR
| edit |
| Protein srodan sa insulinskim receptorom | |||
|---|---|---|---|
| Identifikatori | |||
| Simboli | INSRR; IRR | ||
| Vanjski ID | OMIM: 147671 MGI: 1346037 HomoloGene: 56539 GeneCards: INSRR Gene | ||
| EC broj | 2.7.10.1 | ||
| Pregled RNK izražavanja | |||
 | |||
| podaci | |||
| Ortolozi | |||
| Vrsta | Čovek | Miš | |
| Entrez | 3645 | 23920 | |
| Ensembl | ENSG00000027644 | ENSMUSG00000005640 | |
| UniProt | P14616 | Q9WTL4 | |
| Ref. Sekv. (iRNK) | NM_014215 | NM_011832 | |
| Ref. Sekv. (protein) | NP_055030 | NP_035962 | |
| Lokacija (UCSC) | Chr 1: 156.81 - 156.83 Mb | Chr 3: 87.8 - 87.82 Mb | |
| PubMed pretraga | [1] | [2] | |
Protein srodan sa insulinskim receptorom je protein koji je kod ljudi kodiran INSRR genom.[1][2][3]
- ↑ Shier P, Watt VM (Oct 1989). „Primary structure of a putative receptor for a ligand of the insulin family”. J Biol Chem 264 (25): 14605–8. PMID 2768234.
- ↑ Shier P, Willard HF, Watt VM (Jan 1991). „Localization of the insulin receptor-related receptor gene to human chromosome 1”. Cytogenet Cell Genet 54 (1–2): 80–1. DOI:10.1159/000132963. PMID 2249481.
- ↑ „Entrez Gene: INSRR insulin receptor-related receptor”.
- Zhang B, Roth RA (1992). „The insulin receptor-related receptor. Tissue expression, ligand binding specificity, and signaling capabilities”. J. Biol. Chem. 267 (26): 18320–8. PMID 1326521.
- Mathi SK, Chan J, Watt VM (1995). „Insulin receptor-related receptor messenger ribonucleic acid: quantitative distribution and localization to subpopulations of epithelial cells in stomach and kidney”. Endocrinology 136 (9): 4125–32. DOI:10.1210/en.136.9.4125. PMID 7649121.
- Kovacina KS, Roth RA (1995). „Characterization of the endogenous insulin receptor-related receptor in neuroblastomas”. J. Biol. Chem. 270 (4): 1881–7. DOI:10.1074/jbc.270.4.1881. PMID 7829525.
- Jui HY, Accili D, Taylor SI (1996). „Characterization of a hybrid receptor formed by dimerization of the insulin receptor-related receptor (IRR) with the insulin receptor (IR): coexpression of cDNAs encoding human IRR and human IR in NIH-3T3 cells”. Biochemistry 35 (45): 14326–30. DOI:10.1021/bi9613032. PMID 8916919.
- Hänze J, Berthold A, Klammt J i dr.. (1999). „Cloning and sequencing of the complete cDNA encoding the human insulin receptor related receptor”. Horm. Metab. Res. 31 (2–3): 77–9. DOI:10.1055/s-2007-978702. PMID 10226785.
- Xu P, Jacobs AR, Taylor SI (1999). „Interaction of insulin receptor substrate 3 with insulin receptor, insulin receptor-related receptor, insulin-like growth factor-1 receptor, and downstream signaling proteins”. J. Biol. Chem. 274 (21): 15262–70. DOI:10.1074/jbc.274.21.15262. PMID 10329736.
- Elmlinger MW, Rauschnabel U, Koscielniak E i dr.. (1999). „Correlation of type I insulin-like growth factor receptor (IGF-I-R) and insulin receptor-related receptor (IRR) messenger RNA levels in tumor cell lines from pediatric tumors of neuronal origin”. Regul. Pept. 84 (1–3): 37–42. DOI:10.1016/S0167-0115(99)00065-8. PMID 10535406.
- Whitmore TE, Maurer MF, Day HL i dr.. (2000). „The assignment of the human insulin receptor-related receptor gene (INSRR) to chromosome 1q21→q23 by the use of radiation hybrid mapping”. Cytogenet. Cell Genet. 87 (1–2): 93–4. DOI:10.1159/000015400. PMID 10640820.
- Weber A, Huesken C, Bergmann E i dr.. (2004). „Coexpression of insulin receptor-related receptor and insulin-like growth factor 1 receptor correlates with enhanced apoptosis and dedifferentiation in human neuroblastomas”. Clin. Cancer Res. 9 (15): 5683–92. PMID 14654552.
- Klammt J, Garten A, Barnikol-Oettler A i dr.. (2005). „Comparative analysis of the signaling capabilities of the insulin receptor-related receptor”. Biochem. Biophys. Res. Commun. 327 (2): 557–64. DOI:10.1016/j.bbrc.2004.12.039. PMID 15629149.
- Dissen GA, Garcia-Rudaz C, Tapia V i dr.. (2006). „Expression of the insulin receptor-related receptor is induced by the preovulatory surge of luteinizing hormone in thecal-interstitial cells of the rat ovary”. Endocrinology 147 (1): 155–65. DOI:10.1210/en.2005-0386. PMID 16195402.