RESUMO Objetivo: Relatar dois casos de pneumotórax bilateral espontâneo múltiplo sucessivo em crianças com envolvimento pulmonar maciço por histiocitose de células de Langerhans (HCL), alertando para a possibilidade desse diagnóstico diferencial para o pediatra geral. Ademais, casos publicados que descrevem pacientes pediátricos com manifestações pulmonares de HCL foram revisados na literatura. Descrição do caso: Caso 1: Paciente masculino, três anos, com episódio súbito pneumotórax espontâneo à direita, drenado cirurgicamente. Após dois meses, apresentou dois novos episódios de pneumotórax contralateral. Biópsia linfonodal pulmonar revelou diagnóstico de HCL. Foi submetido a cirurgia torácica assistida por vídeo (VATS) bilateral e minitoracotomia com pleurodese mecânica, além de tratamento quimioterápico, necessitando de internação prolongada. Caso 2: Menino, quatro anos, apresentando dispneia progressiva e sibilância por cinco meses. Biópsia pulmonar revelou HCL. Evoluiu com importante desconforto respiratório e pneumotórax direito, necessitando drenagem. Foi realizada pleurodese com nitrato de prata e diferentes esquemas de quimioterapia. Ambos os pacientes evoluíram bem após tratamentos quimioterápicos múltiplos, cirurgias e suporte intensivo. Comentários: A HCL é uma doença desafiadora. Sua manifestação clínica é variável, e o envolvimento pulmonar ocorre em cerca de 10–15% dos casos. Consideram-se o manejo cirúrgico especializado e o suporte multidisciplinar essenciais para o tratamento de pacientes com HCL pulmonar maciça. Ainda que raro, o envolvimento pulmonar maciço por HCL deve ser considerado em quadros de pneumotórax recorrentes em crianças. Objetivo HCL, , (HCL) geral Ademais literatura caso 1 masculino anos direita cirurgicamente meses contralateral VATS (VATS mecânica quimioterápico prolongada 2 Menino direito drenagem quimioterapia múltiplos intensivo Comentários desafiadora variável 1015 10 15 10–15 Consideramse Consideram se maciça raro (HCL 101 10–1 10–

ABSTRACT Objective: The objective of this study was to report two cases of successive multiple spontaneous bilateral pneumothorax in children with massive lung involvement due to Langerhans cell histiocytosis (LCH), emphasizing the possibility of this differential diagnosis for the general pediatrician. Additionally, published cases describing pediatric patients with pulmonary manifestations of LCH were reviewed in the literature. Case description: Case #1: A 3-year-old male patient with a sudden episode of spontaneous right-sided pneumothorax, surgically drained. After 2 months, he experienced two new episodes of contralateral pneumothorax. A pulmonary lymph node biopsy revealed the diagnosis of LCH. He underwent bilateral video-assisted thoracic surgery and mini-thoracotomy with mechanical pleurodesis, in addition to chemotherapy, requiring prolonged hospitalization. Case #2: A 4-year-old boy with progressive dyspnea and wheezing for 5 months. A pulmonary biopsy revealed LCH. He developed significant respiratory distress and right pneumothorax, requiring drainage. Silver nitrate pleurodesis and different chemotherapy regimens were performed. Both patients responded well to multiple chemotherapy treatments, surgeries, and intensive care support. Comments: LCH is a challenging disease. Its clinical manifestation is variable, and pulmonary involvement occurs in about 10–15% of cases. We consider specialized surgical management and multidisciplinary support essential for the treatment of patients with massive pulmonary LCH. Although rare, massive pulmonary involvement by LCH should be considered in cases of recurrent pneumothorax in children. Objective LCH, , (LCH) pediatrician Additionally literature description #1 1 3yearold yearold 3 year old rightsided sided drained months videoassisted video assisted minithoracotomy mini thoracotomy hospitalization #2 4yearold 4 drainage performed treatments surgeries Comments disease variable 1015 10 15 10–15 rare (LCH # 101 10–1 10–

Resumo Objetivo Investigar a epidemiologia dos tipos de lesões entre praticantes de jiu-jitsu e sua incidência em diferentes níveis de habilidade e experiência por meio da questão: "Quais as características e a prevalência das lesões musculoesqueléticas em praticantes de jiu-jitsu?" Métodos Desde o início do estudo, em agosto de 2020, foram pesquisados os bancos de dados MEDLINE, LILACS e SciELO. Foram incluídos estudos transversais, publicados entre 2018 e 2023, que investigaram a epidemiologia dos tipos de lesões ocorridas entre praticantes de jiu-jitsu e compararam sua incidência em diferentes níveis de habilidade e experiência. Para tanto, dois pesquisadores independentes realizaram a extração dos dados e avaliaram o risco de viés. Resultados Sete estudos foram incluídos. Os resultados comuns envolveram 2.847 praticantes de jiu-jitsu. Houve uma alta prevalência de lesão na articulação do joelho e nas áreas do tórax e das costelas. Considerando a diferença de nível de experiência entre os praticantes, pôde-se observar que a maioria dos indivíduos incluídos eram iniciantes. Entre as faixas etárias observadas, homens acima de 30 anos de idade foram os que mais apresentaram lesões musculoesqueléticas, principalmente durante os treinos. Conclusão Houve uma alta prevalência de lesões musculoesqueléticas entre os praticantes de jiu-jitsu. Os segmentos anatômicos mais acometidos foram a articulação do joelho, o tórax e a região das costelas, seguidos da articulação do ombro. Os fatores relacionados mudaram de acordo com algumas variáveis, sendo mais comuns durante o treinamento em indivíduos do sexo masculino com mais de 30 anos e iniciantes na modalidade. jiujitsu jiu jitsu questão Quais jiu-jitsu? estudo 2020 MEDLINE SciELO transversais 201 2023 tanto viés 2847 2 847 2.84 jiujitsu. jitsu. costelas pôdese pôde se observadas 3 treinos ombro variáveis modalidade 202 20 284 84 2.8 28 8 2.

Abstract Objective To investigate the epidemiology of injury types among jiu-jitsu practitioners, as well as the incidence regarding different skill and experience levels, through the question: "What are the characteristics and prevalence of musculoskeletal injuries in Jiu-Jitsu practitioners?". Methods Since the beginning of the study, in August 2020, we conducted a search on the MEDLINE, LILACS, and SciELO electronic databases. We included cross-sectional studies published between 2018 and 2023 on the epidemiology of the types of injuries among jiu-jitsu practitioners that compared their incidence regarding different levels of ability and experience. Two independent researchers performed the data extraction and assessed the risk of bias. Results Seven studies were included. The common outcomes involved 2,847 jiu-jitsu practitioners. A high prevalence in the knee joint and chest and rib areas was reported. Considering the difference in experience level among the practitioners, we could observe that most of the individuals included were beginners. Among the age groups observed, male practitioners older than 30 years of age were the ones who presented the highest rate of musculoskeletal injury, especially during training sessions. Conclusion There is a high prevalence of musculoskeletal injuries among jiu-jitsu practitioners. The most affected anatomical segments are the knee joint, the chest, and the rib region, followed by the shoulder joint. The related factors change according to certain variables, being more common during training in male individuals over 30 years of age and beginners in the sport. jiujitsu jiu jitsu question What JiuJitsu Jiu Jitsu . practitioners?" study 2020 MEDLINE LILACS databases crosssectional cross sectional 201 202 bias 2847 2 847 2,84 reported observed 3 sessions region variables sport practitioners? 20 284 84 2,8 28 8 2,

Resumo A estomatite química é um tipo de lesão traumática causada pelo contato de substâncias químicas e medicamentos com os tecidos bucais, resultando em danos clinicamente significativos. Nesse contexto, é relatado o caso de um paciente do sexo masculino com 14 anos, portador de doença renal crónica, em terapia renal substitutiva (diálise peritoneal) e uso de carbonato de cálcio via cápsulas orais para tratamento. Devido a complicações da diálise peritoneal, o paciente apresentou um quadro de peritonite bacteriana, necessitando de internamento em unidade de terapia intensiva e alteração do modo de terapia dialítica para hemodiálise. Durante o período de internamento, foi observado o desenvolvimento de lesões orais significativas devido à administração inadequada de carbonato de cálcio, interferindo na evolução do estado geral de saúde do paciente e exigindo a assistência de uma equipa odontológica para diagnóstico e tratamento. O paciente foi diagnosticado com estomatite química. Durante o exame clínico foi possível observar a presença de lesões ulceradas e hemorrágicas localizadas no lábio, mucosas jugais, palato duro e palato mole. A fotobiomodulação a laser foi utilizada como tratamento associada ao corticosteróide. Cada região recebeu dez pontos de 1 J, de forma que foram fornecidos 60 J de energia por dia/sessão. No total, foram fornecidos 480 J de energia com um tempo total de irradiação de 4800 s. O paciente relatou melhora considerável dos sintomas álgicos após a primeira sessão de fotobiomodulação a laser. Após 8 sessões, o paciente melhorou e a fotobiomodulação a laser mostrou-se eficaz no tratamento de lesões orais

Abstract Chemical stomatitis is a type of traumatic injury caused by contact of chemical substances and drugs with oral tissues, resulting in clinically significant damage. This case reports a 14-year-old male patient with chronic kidney disease on renal replacement therapy (peritoneal dialysis) and using calcium carbonate via oral capsules for treatment. Due to peritoneal dialysis complications, the patient developed bacterial peritonitis, requiring intensive care unit admission and alteration of his dialysis therapy mode to hemodialysis. During the hospitalization period, significant oral lesions developed due to inadequate calcium carbonate administration, interfering with the evolution of the patient’s general health and requiring the assistance of a dental team for diagnosis and treatment. The patient was diagnosed with chemical stomatitis. During the clinical examination, ulcerated, bleeding lesions were observed on the lip, jugal mucous membranes, hard palate, and soft palate. Laser photobiomodulation was used as a treatment associated with a topical corticosteroid. Each region received ten 1 J/point, and 60 J of energy were delivered per day/session. In total, 480 J of energy were delivered with a total irradiation time of 4800 s. The patient reported considerable improvement in pain symptoms after the first laser-photobiomodulation session. After 8 sessions, the patient had improved, and laser photobiomodulation proved effective for treating oral lesions.

ABSTRACT BACKGROUND: Nutritional status and growth curves can affect cognitive development, increase the risk of infection, and contribute to the development of chronic diseases. Its etiology is related to food, socioeconomic, and maternal conditions. However, to date, no data on these parameters exist in the state of Goiás, Brazil. OBJECTIVE: To compare the nutritional status and growth curves of children and adolescents in the city of Goiânia, Goiás, Brazil. DESIGN AND SETTING: This was a cross-sectional study. A total of 529 individuals were recruited from a primary health center in the municipality. METHODS: To assess nutritional status, the sample was divided into three categories: 3–4, 5–10, and 11–19 years, with z-score classification considering body mass index for age. The classification of growth curves was performed considering the median height values for age, assuming two references: (a) young Brazilian population and (b) one recommended for international use. The independent sample T-test was used to compare anthropometric variables. RESULTS: The results showed that the classification of eutrophics represents a predominant percentage between both sexes (men: 03–04 = 55.4%; 05–10 = 57.6%; 11–19 = 53.5 % and women: 03–04 = 53.5%; 05–10 = 63.9%; 11–19 = 56.9%), and growth curves showed differences in specific periods in both sexes. CONCLUSIONS: It can be concluded that children and adolescents from the city of Goiânia present as predominance the eutrophic nutritional status, followed by the risk of overweight, underweight, obesity, and malnutrition of both sexes. BACKGROUND infection diseases food socioeconomic conditions However date Goiás Brazil OBJECTIVE SETTING crosssectional cross sectional study 52 municipality METHODS categories 34 3 4 3–4 510 5 10 5–10 1119 11 19 11–1 years zscore z score age references (a b (b use Ttest T test variables RESULTS men (men 0304 03 04 03–0 55.4% 554 55 0510 05 05–1 57.6% 576 57 6 535 53 53. women 53.5% 63.9% 639 63 9 56.9%, 569 56.9% , 56 56.9%) CONCLUSIONS overweight underweight obesity 3– 51 1 5–1 111 11– 030 0 03– 55.4 051 05– 57.6 63.9 56.9 5– 55. 57. 63. 56.

RESUMO: Quando aplicado na fase de crescimento, o programa de luz visa obter codornas com peso corporal e maturidade fisiológica adequados para o início da postura. Este estudo avaliou programas de iluminação na fase de crescimento sobre o desempenho, maturidade sexual e qualidade dos ovos de codornas de corte reprodutoras (Coturnix coturnix) na fase de postura. Durante o período de sete a 49 dias de idade, 300 codornas de corte fêmeas foram submetidas a três programas de iluminação (natural, intermitente e contínuo), com cinco repetições de 20 aves cada. Aos 49 dias de idade, 240 codornas foram transferidas para um galpão, mantendo a mesma distribuição experimental e submetidas às mesmas condições. As aves submetidas aos programas de iluminação contínuo e intermitente na fase de crescimento apresentaram maiores peso relativo do sistema reprodutivo e consequentemente menores idades para produção do primeiro ovo e para atingir 50% da produção de ovos (P < 0.05). As aves que receberam apenas iluminação natural apresentaram menor consumo de ração nos períodos de 49 a 70 e 71 a 92 dias de idade e pior conversão alimentar até 114 dias de idade. Os programas de iluminação contínua e intermitente na fase de crescimento resultaram em codornas mais precoces quando comparados as aves submetidas ao programa de iluminação natural. Codornas submetidas a programa de luz natural na fase de crescimento apresentaram menor produção de ovos durante todos os períodos, não diferindo das aves submetidas a programas contínuos e intermitentes a partir do segundo período (71 a 92 dias de idade). A iluminação intermitente e contínua na fase de crescimento resulta em melhor conversão alimentar de codornas reprodutoras até 114 dias e maior percentual de postura (49 a 136 dias), reduzindo o número de dias para produzir o primeiro ovo e atingir 50% de postura, em relação a iluminação natural.. RESUMO desempenho Coturnix coturnix 4 30 natural, (natural contínuo, , contínuo) 2 cada 24 galpão condições 50 P 0.05. 005 0.05 . 0 05 0.05) 7 9 11 (7 idade) (4 13 dias, dias) 3 5 00 0.0 1 ( 0.

ABSTRACT: When applied at growing phase, lighting program aims to obtain quails with body weight and physiological maturity suitable for the beginning of laying. This study evaluated lighting programs at growing phase on performance, sexual maturity and egg quality of meat quail breeders (Coturnixcoturnix) at laying phase. From 7 to 49 days of age, 300 female meat quails were subjected to three lighting programs (natural, intermittent and continuous), with 5 replicates of 20 birds each. At 49 days of age, 240 quails were transferred to a shed, maintaining the same experimental conditions. Meat quails submitted to continuous and intermittent lighting programs had higher weight of reproductive system and lower ages for first egg production and to reach 50% of egg production (P < 0.05). Quails submitted to natural lighting had lower feed intake from 49 to 70 and 71 to 92 days of age and worse feed conversion up to 114 days of age. Continuous and intermittent lighting programs resulted in more precocious quails compared to natural lighting program. Quails submitted to natural lighting at growing phase presented lower egg production during all periods, not differing for birds submitted to continuous and intermittent programs from the second period (71 to 92 days of age). Intermittent and continuous lighting result in better feed conversion of breeding quails up to 114 days and a higher percentage of laying (49 to 136 days), reducing the number of days to produce the first egg and to reach 50% of laying, in relation to natural lighting. ABSTRACT performance Coturnixcoturnix (Coturnixcoturnix 4 30 natural, (natural continuous, , continuous) 2 each 24 shed conditions 50 P 0.05. 005 0.05 . 0 05 0.05) 9 11 periods (7 age) (4 13 days, days) 3 00 0.0 1 ( 0.

ABSTRACT The use of non-conventional feeds in poultry farming can reduce production costs, mainly because of its low cost, availability and chemical composition. Thus, parboiled whole rice bran (PWRB) appears as a potential use in feeding quails. Two experiments were carried out to evaluate the effects of the inclusion of PWRB in the diet of quails. In each experiment, a total of 288 seven-day-old European quails of both sexes, were distributed in a completely randomized design with six treatments and six replicates of eight quails each. The treatments consisted in the inclusion of PWRB in the proportions of 0; 5; 10; 15; 20 and 25% (first) and 0; 8; 16; 24; 32 and 40% (second). In the first experiment, a linear reduction in feed intake and weight gain was observed with the inclusion of PWRB above 5%, with no significant effect on feed conversion and carcass characteristics. However, there was no loss in the performance and carcass characteristics of quails fed with different levels of PWRB in comparison to the control group. In the second, it was observed that the inclusion of PWRB above 8% promoted a linear reduction in feed intake, weight gain and improvement in feed conversion, with no significant effect on carcass characteristics. However, quails fed 40% PWRB showed reduced intake and weight gain when compared to the control group. The use of PWRB provided an improvement in economic viability. Considering the effect on growth, PWRB can be used in the feeding of meat quails up to 32%. nonconventional non conventional costs cost composition Thus (PWRB experiment 28 sevendayold seven day old sexes 0 5 10 15 2 25 (first 8 16 24 3 40 second. second . (second) 5% However group viability growth 32% 1 4 (second

Resumo O objetivo deste trabalho foi avaliar o efeito da adição dietética de anacardato de cálcio como fonte de ácido anacárdico sobre o desempenho reprodutivo e os parâmetros antioxidantes sanguíneos de coelhas Nova Zelândia Branco. Vinte e sete fêmeas da raça Nova Zelândia Branco foram distribuídas em delineamento em blocos ao acaso, com três tratamentos e nove repetições, tendo-se considerado um animal como unidade experimental. Os tratamentos consistiram em rações peletizadas, com diferentes níveis de inclusão de anacardato de cálcio (0, 0,5 e 1,0%). A inclusão de anacardato de cálcio nas dietas aumentou a concentração de compostos fenólicos e a capacidade antioxidante no sangue das coelhas fêmeas lactantes. O anacardato de cálcio ao nível de 1,0% melhora a conversão alimentar durante a gestação e aumenta os compostos fenólicos e a capacidade antioxidante no soro sanguíneo das coelhas aos 21 dias de lactação. acaso repetições tendose tendo se experimental peletizadas 0, 0 (0 05 5 1,0%. 10 . 1 1,0%) lactantes 1,0 2 lactação ( 1,

Abstract The objective of this work was to evaluate the effect of the dietary addition of calcium anacardate as a source of phenolic compounds on the reproductive performance and blood antioxidant parameters of New Zealand White female rabbits. Twenty-seven New Zealand White female rabbits were distributed in a randomized complete block design with three treatments and nine replicates, considering one animal as the experimental unit. The treatments consisted of pelleted diets with different inclusion levels of calcium anacardate (0, 0.5, and 1.0%). The inclusion of calcium anacardate in the diets increased the concentration of phenolic compounds and the antioxidant capacity in the blood of lactating female rabbits. Calcium anacardate at the level of 1.0% improves the feed conversion ratio during gestation and increases the phenolic compounds and antioxidant capacity in the blood serum of female rabbits at 21 days of lactation. Twentyseven Twenty seven replicates unit 0, 0 (0 05 5 0.5 1.0%. 10 . 1 1.0%) 1.0 2 lactation ( 0. 1.

RESUMO Este relato apresenta o caso de um paciente adulto com limitações mentais e intelectuais, cuja queixa principal era a estética dental. O tratamento odontológico foi realizado na Faculdade de Odontologia de Piracicaba e aprovado pelo Comitê de Ética (CAAE: 65752322.2.0000.5418). Clinicamente, o paciente apresentava inadequações no arranjo dentário, com comprometimento periodontal, que colocava em risco os elementos dentais. Nos aspectos clínicos intrabucais, a deficiência foi identificada como atresia maxilar. A inclinação vestíbulo-lingual dos dentes anteriores inferiores destacou o apinhamento severo e o cruzamento anterior desses dentes. O tratamento odontológico foi realizado visando à remissão dos problemas periodontais e ortodônticos de forma integrada e com abordagens que permitissem maior interação, participação e adesão do paciente durante o tratamento. Foram realizadas raspagens supra e subgengivais e extração do incisivo lateral superior esquerdo. Após três meses de tratamento periodontal, iniciou-se o tratamento ortodôntico com aparelhos ortodônticos fixos. O objetivo principal foi nivelar e alinhar os dentes em ambas as arcadas para alcançar melhores condições estéticas e funcionais. Devido à pandemia de COVID-19, o tratamento foi interrompido. Isso resultou na regressão dos resultados obtidos, inclusive quanto ao autocuidado. As pessoas com deficiência requerem atendimento odontológico com estratégias específicas para suas necessidades, que devem ser realizadas por uma equipe multidisciplinar. Apesar da limitação de acesso imposta pela pandemia, o paciente restabeleceu sua motivação para reiniciar o tratamento, o que foi facilitado pelo vínculo de confiança estabelecido entre ele e a equipe. intelectuais dental CAAE (CAAE 65752322.2.0000.5418. 65752322200005418 65752322.2.0000.5418 . 65752322 2 0000 5418 65752322.2.0000.5418) Clinicamente dentário periodontal dentais intrabucais maxilar vestíbulolingual vestíbulo lingual interação esquerdo iniciouse iniciou se fixos funcionais COVID19, COVID19 COVID 19, 19 COVID-19 interrompido obtidos autocuidado necessidades multidisciplinar 6575232220000541 65752322.2.0000.541 6575232 000 541 COVID1 1 COVID-1 657523222000054 65752322.2.0000.54 657523 00 54 COVID- 65752322200005 65752322.2.0000.5 65752 0 5 6575232220000 65752322.2.0000. 6575 657523222000 65752322.2.0000 657 65752322200 65752322.2.000 65 6575232220 65752322.2.00 6 657523222 65752322.2.0 65752322.2. 65752322.2 65752322.

ABSTRACT This report presents the case of an adult patient with mental and intellectual limitations, whose main complaint was dental aesthetics. Dental treatment was performed at the Piracicaba Dental School and approved by the Ethics Committee (CAAE: 65752322.2.0000.5418). Clinically, the patient had inadequacies in the dental arrangement, with periodontal involvement that put the dental elements at risk. In intraoral clinical aspects, the deficiency was identified as maxillary atresia. The buccolingual inclination of the mandibular anterior teeth highlighted the severe crowding and anterior crossing of these teeth. Dental treatment was carried out aiming at the remission of periodontal and orthodontic problems in an integrated manner and with approaches that allowed greater interaction, participation, and patient compliance during treatment. Supra and subgingival scrapings and extraction of the upper left lateral incisor were performed. After three months of periodontal treatment, orthodontic treatment was started with fixed orthodontic appliances. The main objective was to level and align the teeth in both arches to achieve better aesthetic and functional conditions. Due to the COVID-19 pandemic, treatment has been discontinued. This resulted in the regression of the results obtained, including regarding self-care. People with disabilities require dental care with specific strategies for their needs, which must be carried out by a multidisciplinary team. Despite the access limitation imposed by the pandemic, the patient reestablished his motivation to restart treatment, which was facilitated by the bond of trust established between him and the team. limitations aesthetics CAAE (CAAE 65752322.2.0000.5418. 65752322200005418 65752322.2.0000.5418 . 65752322 2 0000 5418 65752322.2.0000.5418) Clinically arrangement risk aspects atresia interaction participation appliances conditions COVID19 COVID 19 COVID-1 pandemic discontinued obtained selfcare. selfcare self care. self-care needs team 6575232220000541 65752322.2.0000.541 6575232 000 541 COVID1 1 COVID- 657523222000054 65752322.2.0000.54 657523 00 54 65752322200005 65752322.2.0000.5 65752 0 5 6575232220000 65752322.2.0000. 6575 657523222000 65752322.2.0000 657 65752322200 65752322.2.000 65 6575232220 65752322.2.00 6 657523222 65752322.2.0 65752322.2. 65752322.2 65752322.

Abstract Background: In this experimental protocol, we evaluated the immediate and delayed repair of the buccal branch of the facial nerve (BBFN) with heterologous fibrin biopolymer (HFB) as a coaptation medium and the use of photobiomodulation (PBM), performing functional and histomorphometric analysis of the BBFN and perioral muscles. Methods: Twenty-eight rats were divided into eight groups using the BBFN bilaterally (the left nerve was used for PBM), namely: G1 - control group, right BBFN (without injury); G2 - control group, left BBFN (without injury + PBM); G3 - Denervated right BBFN (neurotmesis); G4 - Denervated left BBFN (neurotmesis + PBM); G5 - Immediate repair of right BBFN (neurotmesis + HFB); G6 - Immediate repair of left BBFN (neurotmesis + HFB + PBM); G7 - Delayed repair of right BBFN (neurotmesis + HFB); G8 - Delayed repair of left BBFN (neurotmesis + HFB + PBM). Delayed repair occurred after two weeks of denervation. All animals were sacrificed after six weeks postoperatively. Results: In the parameters of the BBFN, we observed inferior results in the groups with delayed repair, in relation to the groups with immediate repair, with a significant difference (p < 0.05) in the diameter of the nerve fiber, the axon, and the thickness of the myelin sheath of the group with immediate repair with PBM compared to the other experimental groups. In measuring the muscle fiber area, groups G7 (826.4 ± 69.90) and G8 (836.7 ± 96.44) were similar to G5 (882.8 ± 70.51). In the functional analysis, the G7 (4.10 ± 0.07) and G8 (4.12 ± 0.08) groups presented normal parameters. Conclusion: We demonstrated that delayed repair of BBFN is possible with HFB, but with worse results compared to immediate repair, and that PBM has a positive influence on nerve regeneration results in immediate repair. Background protocol (BBFN (HFB PBM, , (PBM) muscles Methods Twentyeight Twenty PBM) namely G without injury) neurotmesis (neurotmesis) HFB) PBM. . denervation postoperatively Results p 0.05 005 0 05 axon area 826.4 8264 826 4 (826. 69.90 6990 69 90 836.7 8367 836 7 (836. 96.44 9644 96 44 882.8 8828 882 8 (882. 70.51. 7051 70.51 70 51 70.51) 4.10 410 10 (4.1 0.07 007 07 4.12 412 12 0.08 008 08 Conclusion (PBM 0.0 00 826. 82 (826 69.9 699 6 9 836. 83 (836 96.4 964 882. 88 (882 705 70.5 5 4.1 41 1 (4. 0. (82 69. (83 96. (88 70. 4. (4 (8 (

ABSTRACT. Food production in a sustainable way is based on the association between animals and vegetables to minimize costs, environmental impact, and the use of insums in the breeding process. The objective of this work was to evaluate the effect of the inclusion of pumpkin seed flour (Cucurbita pepo L.) in the diet on the performance of early-stage pigs and the reduction of endoparasites in a commercial rearing system. The experimental design was completely randomized, with three treatments and six replicates, and the experimental unit consisted of two animals, totaling 36 animals. The treatments were the basal diet and two levels of inclusion of pumpkin seed: 5 and 10%. The animals were of the Agroceres line, with 42 days of age and an average weight of 12 kg. The animals and rations were weighed at the beginning and at the end of the 35-day experimental period to obtain the performance variables. A bromatological analysis was performed to evaluate the composition of pumpkin seed and for parasitic analysis, feces were collected individually from the animal. There was no significant effect for the Tukey test at the level of 5% probability, of the inclusion of pumpkin seed flour on in the parameters of weight gain and feed conversion. Was observed the reduction of helminth eggs present in feces using egg count and oocysts per gram of feces (OPG), performed at the beginning and end of the experiment. It is indicated the inclusion of 10% of pumpkin flour in the feeding of pigs in the initial phase by reducing contamination by verminosis and does not alter animal performance. ABSTRACT costs impact process Cucurbita L. L earlystage early stage system randomized replicates 3 10 line 4 1 kg 35day day 35 variables probability conversion OPG, OPG , (OPG) experiment (OPG

ABSTRACT Heart failure is the leading cause of cardiac-related hospitalizations. Limited access to reevaluations and outpatient appointments restricts the application of modern therapies. Telemedicine has become an essential resource in the healthcare system because of its countless benefits, such as higher and more frequent appointments and faster titration of medications. This narrative review aimed to demonstrate the evidence and unresolved issues related to the use of telemedicine in patients with heart failure. No studies have examined heart failure prevention; however, several studies have addressed the prevention of decompensation with positive results. Telemedicine can be used to evaluate all patients with heart failure, and many telemedicine platforms are available. Several strategies, including both noninvasive (phone calls, weight measurement, and virtual visits) and invasive (implantable pulmonary artery catheters) strategies can be implemented. Given these benefits, telemedicine is highly desirable, particularly for vulnerable groups. Although some questions remain unanswered, the development of new technologies can complement remote visits and improve patient care. cardiacrelated cardiac hospitalizations therapies benefits medications however results available phone calls measurement implantable catheters implemented desirable groups unanswered care

ABSTRACT This study aimed to assess the effect of different doses and times of application of the growth regulator trinexapac-ethyl on the productive performance of white oat cultivars. The experiment was carried out in Londrina, Paraná State, Brazil, in the 2019 and 2020 seasons using the white oat cultivars IPR Artemis and URS Corona. The experimental design was a randomized block with four replications arranged in a 4 × 3 factorial scheme, conducted separately for each cultivar, with four doses of trinexapac-ethyl (0, 50, 100, and 150 g ha-1) and three times of application (T1, first node noticeable; T2, first node visible and second node noticeable; and T3, second node visible and third node noticeable). The following agronomic characters were evaluated: plant height, panicle length, panicles per square meter, spikelets per panicle, grains per spikelet, grains per panicle, thousand grain weight,lodging percentage, and grain yield. Application of trinexapac-ethyl at doses of 100 or 150 g ha-1 at T2 or T3 reduced panicle length, spikelets per panicle, and grains per panicle in IPR Artemis and URS Corona. However, it also reduced plant height and increased panicles per square meter and yield in both cultivars. These same doses and times of application resulted in a significant reduction in lodging. trinexapacethyl trinexapac ethyl Londrina State Brazil 201 202 Corona scheme cultivar 0, 0 (0 50 15 ha1 ha 1 T1, T1 T (T1 noticeable noticeable. . noticeable) evaluated length spikelet weightlodging weight lodging percentage 10 ha- However 20 ( 5 (T 2

RESUMO Objetivo: Avaliar e correlacionar o equilíbrio sagital com parâmetros posturais da pelve e coluna lombar Métodos: Foram avaliados 80 indivíduos de ambos os sexos, com idade entre 20 e 35 anos. A biofotogrametria foi realizada com o software SAPO. As medidas dos parâmetros do equilíbrio sagital foram obtidas pela análise de uma radiografia panorâmica em perfil da coluna vertebral, na qual os pontos anatômicos de referência foram marcados digitalmente. O cálculo dos ângulos foi feito automaticamente pelo programa Keops. Resultados: Na avaliação Keops, 17,5% da amostra apresentavam ângulos de incidência pélvicos altos (> 60°), 31,5% tinham ângulos de incidência pélvicos baixos (< 45°) e 51,2% apresentavam ângulos de incidência pélvicos médios (entre 46° e 59°). O SAPO apresentou 12,5% de lordose, 40% de retroversão e 47,5% de curvatura normal. Na vista lateral direita, o ângulo de incidência da pelve apresentou correlação moderada e positiva com o alinhamento vertical do tronco e com o alinhamento vertical do corpo e negativa e moderada com o alinhamento horizontal da pelve. Conclusão: Foram encontradas diferenças entre as medidas de alinhamento vertical do sistema de avaliação postural (SAPO). Uma correlação positiva foi encontrada entre IP de Keops e anteversão pélvica de SAPO. Nível de Evidência II; Estudo Prospectivo. Objetivo Métodos 8 sexos 2 3 anos vertebral digitalmente Resultados 175 17 5 17,5 > ( 60°, 60 60° , 60°) 315 31 31,5 < 45° 45 512 51 51,2 46 59°. 59 59° . 59°) 125 12 12,5 lordose 40 475 47 47,5 normal direita Conclusão (SAPO) II Prospectivo 1 17, 6 31, 4 51, 12, 47, (SAPO

ABSTRACT Objective: Evaluate and correlate the sagittal balance parameters with the postural of the pelvis and lumbar spine. Methods: 80 individuals of both sexes, aged between 20 and 35 years, were evaluated. Biophotogrammetry was done with the SAPO software program. Measurements of the sagittal balance parameters were obtained by analyzing a lateral view panoramic radiography of the vertebral column, in which the anatomical points of reference were digitally marked. The calculation of the angles was done automatically by the Keops program. Results: In Keops assessment, 17.5% of the sample had high pelvic incidence angles (> 60°), 31.5% had low pelvic incidence angles (< 45°), and 51.2% had medium pelvic incidence angles (between 46° and 59°). SAPO showed 12,5% lordosis, 40% retroversion, and 47,5% normal curvature. In the right lateral view, pelvic incidence angle had a moderate and positive correlation with vertical alignment of the trunk and with vertical alignment of the body, and a negative and moderate correlation with horizontal alignment of the pelvis. Conclusion: Differences were found between vertical alignment measurements from the postural evaluation system (SAPO). A positive correlation was found between PI from Keops and pelvic anteversion from SAPO. Level of Evidence II; Prospective Study. Objective spine Methods 8 sexes 2 3 years evaluated program column marked Results assessment 175 17 5 17.5 > ( 60°, 60 60° , 60°) 315 31 31.5 < 45°, 45 45° 45°) 512 51 51.2 46 59°. 59 59° . 59°) 125 12 12,5 lordosis 40 retroversion 475 47 47,5 curvature body Conclusion (SAPO) II Study 1 17. 6 31. 4 51. 12, 47, (SAPO

Resumo O objetivo do estudo foi validar a metodologia da imunoquimioluminescência (CLIA) através da imunoabsorção enzimática (ELISA), determinando a concentração sérica de progesterona em vacas de leite e de corte, durante o ciclo estral. Foram empregadas 30 vacas multíparas não-prenhes (12 da raça Holandesa Preta e Branca e 18 Nelore). Vacas com corpo luteo foram escolhidas com vistas à sincronização do estro e da ovulação, mediante aplicação de 500 mcg de cloprostenol (im). Após a aplicação do luteolitico, os animais foram diariamente submetidos a exames de ultrasssonagrafia (US) ovariana para verificação da ovulação (=dia 01 do ciclo), bem como eram colhidas 02 amostras de sangue para a determinação da P4 pela CLIA e ELISA. As amostras eram centrifugadas para a obtenção do soro, e congeladas a -20 graus para posterior dosagem. Os valores de ELISA e CLIA foram comparados entre si mediante teste t pareado, regressão, ANOVA e coefficiente de determinação (R2), visando a verificação da sensibilidade e correspondência linear. A concentração de P4 originou perfis similares entre as duas metodologias; os perfis de P4 foram mais elevados em bovinos de corte, que nos de leite. A correspondência entre as metodologias resultou em elevado quociente de R2 nos perfis de P4. Concluiu-se que a CLIA pode ser empregada nas determinações hormonais da P4 serica bovina; a CLIA mostrou elevada correspondência linear com os valores da ELISA; a CLIA pode auxiliar as biotecnicas da reprodução nas determinações hormonais. (CLIA ELISA, , (ELISA) corte estral 3 nãoprenhes não prenhes 12 (1 1 Nelore. Nelore . Nelore) 50 im. im (im) luteolitico US (US =dia dia 0 ciclo, ciclo) P soro 20 -2 dosagem pareado regressão R2, R (R2) Concluiuse Concluiu se bovina (ELISA ( 5 (im 2 - (R2 (R

Abstract This study aimed to validate the methodology of immunochemiluminescence (CLIA) using an enzyme-linked immunosorbent assay (ELISA) to determine serum progesterone (P4) concentrations in non-pregnant multiparous dairy (12 Holstein cows) and beef (18 Nellore cows) cows during the estrous cycle. Cows with corpus luteum were chosen for estrus and ovulation synchronization by administering 500 mcg of cloprostenol. After luteolytic application, the animals were subjected to ovarian ultrasonography (US) daily to verify ovulation (day zero of the cycle) and two blood samples were collected for P4 determination using CLIA and ELISA. Samples were centrifuged to obtain serum and frozen at -20 °C for later measurement. ELISA and CLIA values were compared using the paired t-test, regression, analysis of variance, and coefficient of determination (R2) to verify sensitivity and linear correspondence. The P4 concentration determined by both methodologies showed a similar profile; the P4 profiles were higher in beef cattle than in dairy cattle. The correspondence between the methodologies resulted in a high quotient for R2 the P4 profiles. It was concluded that CLIA can be used for hormonal determinations of bovine serum P4. CLIA showed a high linear correspondence with ELISA values and can thus aid reproductive biotechnologies for hormone determination. (CLIA enzymelinked enzyme linked (ELISA P (P4 nonpregnant non pregnant 12 (1 18 cycle 50 cloprostenol application US (US day 20 -2 C measurement ttest, ttest t test, test t-test regression variance R (R2 profile (P 1 ( 5 2 - (R

RESUMO Popularmente conhecida como ipê-amarelo, Handroanthus chrysotrichus (Mart. ex DC.) Mattos é uma arbórea nativa do Brasil, de florescimento exuberante, usada na arborização de cidades, no reflorestamento de áreas degradadas, além de sua madeira ser destinada para diversos fins. Para o desenvolvimento de plantas vigorosas após o plantio, é importante a produção de mudas de alta qualidade, que podem ser obtidas com o uso de rizobactérias. Consideradas como fontes renováveis, as rizobactérias apresentam propriedades de promoção do crescimento, facilitadoras da absorção e/ou solubilização de nutrientes e contribuem para a produção de fitohormônios, ao mesmo tempo que podem atuarem como controladoras de patógenos e na mitigação de estresse abiótico. Esses atributos juntos possibilitam o estabelecimento de um sistema de produção sustentável para a obtenção de mudas vigorosas e de crescimento rápido. O trabalho teve como objetivo avaliar o efeito de rizobactérias promotoras de crescimento de plantas na produção de mudas de ipê-amarelo. O delineamento experimental foi o inteiramente casualizado. Os tratamentos consistiram nos microrganismos (Bacillus subtilis, Bacillus megaterium, Bacillus amyloliquefaciens e Azospirillum brasilense) mais a ausência de microrganismos – controle; em quatro repetições e dez plantas por parcela. Os parâmetros avalizados foram: altura da parte aérea; diâmetro do coleto; comprimento do sistema radicular; massa seca da parte aérea, das raízes e total; número de folhas e área foliar, além do teor de clorofila; fluorescência mínima e máxima; e máxima eficiência fotoquímica do fotossistema II; razão altura da parte aérea/ diâmetro do coleto e o Índice de Qualidade de Dickson. A inoculação de B. amyloliquefaciens promoveu incremento na altura da muda, no diâmetro do coleto, no comprimento de raiz, na área foliar, na massa seca da parte área, das raízes e total e, também, aumentou o Índice de Qualidade de Dickson. Pode-se concluir que B. amyloliquefaciens é o inoculante mais eficiente para a produção de mudas de ipê-amarelo, seguido por A. brasilense. ipêamarelo, ipêamarelo ipê amarelo, amarelo ipê-amarelo Mart. Mart (Mart DC. DC Brasil exuberante cidades degradadas fins plantio qualidade renováveis eou ou fitohormônios abiótico rápido ipêamarelo. amarelo. casualizado subtilis megaterium brasilense controle parcela foram aérea radicular foliar clorofila II Dickson B muda raiz também Podese Pode se

ABSTRACT Handroanthus chrysotrichus (Mart. ex DC.) Mattos, popularly known as the golden trumpet tree, is a native tree of Brazil with exuberant flowering. It is used for urban afforestation and reforestation of degraded areas, and its wood is destined for several purposes. In order to develop vigorous plants after planting, it is essential to produce high-quality seedlings, which can be obtained using rhizobacteria. As renewable sources, rhizobacteria exhibit growth-promoting properties, facilitate nutrient uptake and/or solubilization, and contributes to the production of phytohormones, while also serving as pathogen controllers and mitigators of abiotic stress. These attributes collectively enable the establishment of a sustainable production system for producing vigorous and rapidly growing seedlings. This study aimed to evaluate the effect of plant growth-promoting rhizobacteria in the production of H. chrysotrichus seedlings. The experimental design followed a completely randomized setup. The treatments consisted of microorganisms (Bacillus subtilis, Bacillus megaterium, Bacillus amyloliquefaciens, and Azospirillum brasilense) plus the absence of microorganisms - control; four repetitions and ten plants-per-plot. The parameters evaluated were shoot height; stem diameter; root length; shoot, root, and total dry matter; leaf number and leaf area, as well as chlorophyll content; minimum and maximum fluorescence; and maximum quantum efficiency of photosystem II; shoot height/stem diameter ratio and Dickson’s Quality Index. The B. amyloliquefaciens inoculation promoted an increase in seedling shoot height, stem diameter, root length, leaf area, shoot, root, and total dry matter and also increased the Dickson Quality Index. It can be concluded that B. amyloliquefaciens is the most efficient inoculant for producing golden trumpet tree seedlings, followed by A. brasilense. Mart. Mart (Mart DC. DC Mattos flowering areas purposes planting highquality high quality seedlings sources growthpromoting growth promoting properties andor or solubilization phytohormones stress H setup subtilis megaterium brasilense control plantsperplot. plantsperplot per plot. plot plants-per-plot height length area content fluorescence II heightstem Dicksons s Index B A