Mitochondrial dysfunction: mechanisms and advances in therapy

Y Zong, H Li, P Liao, L Chen, Y Pan, Y Zheng… - Signal transduction and …, 2024 - nature.com
Mitochondria, with their intricate networks of functions and information processing, are pivotal
in both health regulation and disease progression. Particularly, mitochondrial dysfunctions …

Hyperuricemia and its related diseases: mechanisms and advances in therapy

L Du, Y Zong, H Li, Q Wang, L Xie, B Yang… - … and Targeted Therapy, 2024 - nature.com
Hyperuricemia, characterized by elevated levels of serum uric acid (SUA), is linked to a
spectrum of commodities such as gout, cardiovascular diseases, renal disorders, metabolic …

Glucagon-like peptide-1 receptor: mechanisms and advances in therapy

Z Zheng, Y Zong, Y Ma, Y Tian, Y Pang… - … and Targeted Therapy, 2024 - nature.com
The glucagon-like peptide-1 (GLP-1) receptor, known as GLP-1R, is a vital component of the
G protein-coupled receptor (GPCR) family and is found primarily on the surfaces of various …

Osteocyte mitochondria regulate angiogenesis of transcortical vessels

…, Y Qian, Y Zong, W Zou, H Li, W Zhang, M Yao… - Nature …, 2024 - nature.com
Transcortical vessels (TCVs) provide effective communication between bone marrow vascular
system and external circulation. Although osteocytes are in close contact with them, it is …

Mitochondrial heterogeneity in diseases

L Chen, M Zhou, H Li, D Liu, P Liao, Y Zong… - Signal transduction and …, 2023 - nature.com
As key organelles involved in cellular metabolism, mitochondria frequently undergo adaptive
changes in morphology, components and functions in response to various environmental …

Antibody dynamics to SARS‐CoV‐2 in asymptomatic COVID‐19 infections

…, Z Xu, B Zhang, H Chen, J Xue, X Lin, Y Zheng, Z Yao… - Allergy, 2021 - Wiley Online Library
Background The missing asymptomatic COVID‐19 infections have been overlooked because
of the imperfect sensitivity of the nucleic acid testing (NAT). Globally understanding the …

Regulation of blood-brain barrier integrity by Dmp1-expressing astrocytes through mitochondrial transfer

…, Y Huang, H Zhou, L Shi, J Papadimitriou, Y Zong… - Science …, 2024 - science.org
The blood-brain barrier (BBB) acts as the crucial physical filtration structure in the central
nervous system. Here, we investigate the role of a specific subset of astrocytes in the regulation …

[HTML][HTML] Propagation of bending waves in phononic crystal thin plates with a point defect

ZJ Yao, GL Yu, YS Wang, ZF Shi - International Journal of Solids and …, 2009 - Elsevier
In this paper, the band structures of bending waves in a phononic crystal thin plate with a
point defect are studied using an improved plane wave expansion method combined with the …

A hierarchical deep reinforcement learning framework for 6-DOF UCAV air-to-air combat

J Chai, W Chen, Y Zhu, ZX Yao… - IEEE Transactions on …, 2023 - ieeexplore.ieee.org
Unmanned combat air vehicle (UCAV) combat is a challenging scenario with high-dimensional
continuous state and action space and highly nonlinear dynamics. In this article, we …

Overproduction of OsRACK1A, an effector-targeted scaffold protein promoting OsRBOHB-mediated ROS production, confers rice floral resistance to false smut …

…, X Zhang, J Liu, XH Hu, Y Zhu, S Shen, YF Bai, ZL Yao… - Molecular plant, 2022 - cell.com
Grain formation is fundamental for crop yield but is vulnerable to abiotic and biotic stresses.
Rice grain production is threatened by the false smut fungus Ustilaginoidea virens, which …