Autophagy enhances the replication of classical swine fever virus in vitro
Autophagy plays an important role in cellular responses to pathogens. However, the impact
of the autophagy machinery on classical swine fever virus (CSFV) infection is not yet …
of the autophagy machinery on classical swine fever virus (CSFV) infection is not yet …
Manipulation of PD‐L1 Endosomal Trafficking Promotes Anticancer Immunity
Z Ye, Y Xiong, W Peng, W Wei, L Huang… - Advanced …, 2023 - Wiley Online Library
The aberrant regulation of PD‐L1 in tumor cells remains poorly understood. Here, the authors
systematically investigate the endosomal trafficking of plasma membrane PD‐L1 in tumor …
systematically investigate the endosomal trafficking of plasma membrane PD‐L1 in tumor …
Absence of autophagy promotes apoptosis by modulating the ROS-dependent RLR signaling pathway in classical swine fever virus-infected cells
A growing number of studies have demonstrated that both macroautophagy/autophagy and
apoptosis are important inner mechanisms of cell to maintain homeostasis and participate in …
apoptosis are important inner mechanisms of cell to maintain homeostasis and participate in …
Berbamine inhibits SARS-CoV-2 infection by compromising TRPMLs-mediated endolysosomal trafficking of ACE2
L Huang, TTT Yuen, Z Ye, S Liu, G Zhang… - … and Targeted Therapy, 2021 - nature.com
Middle East respiratory syndrome-related coronavirus (MERS-CoV) is the pathogen responsible
for the outbreak of MERS, and we are currently being affected by coronavirus disease …
for the outbreak of MERS, and we are currently being affected by coronavirus disease …
[HTML][HTML] EBV latent membrane protein 1 augments γδ T cell cytotoxicity against nasopharyngeal carcinoma by induction of butyrophilin molecules
Y Liu, KS Lui, Z Ye, TY Fung, L Chen, PY Sit… - Theranostics, 2023 - ncbi.nlm.nih.gov
Nasopharyngeal carcinoma (NPC) is a diverse cancer with no well-defined tumor antigen,
associated with oncogenic Epstein-Barr Virus (EBV), and with usually late-stage diagnosis …
associated with oncogenic Epstein-Barr Virus (EBV), and with usually late-stage diagnosis …
Berbamine inhibits Japanese encephalitis virus (JEV) infection by compromising TPRMLs-mediated endolysosomal trafficking of low-density lipoprotein receptor …
L Huang, H Li, Z Ye, Q Xu, Q Fu, W Sun… - Emerging Microbes & …, 2021 - Taylor & Francis
Japanese encephalitis virus (JEV), a member of the Flavivirus genus, is an important pathogen
that causes human and animal infectious diseases in Asia. So far, no effective antiviral …
that causes human and animal infectious diseases in Asia. So far, no effective antiviral …
Rapid and simple detection of Japanese encephalitis virus by reverse transcription loop-mediated isothermal amplification combined with a lateral flow dipstick
Japanese encephalitis virus (JEV) is a major cause of viral encephalitis in geographical
areas, such as Asia and Western Pacific, where it is a threat to human and animal health. To …
areas, such as Asia and Western Pacific, where it is a threat to human and animal health. To …
Vacuolin-1 inhibits endosomal trafficking and metastasis via CapZβ
Z Ye, D Wang, Y Lu, Y He, J Yu, W Wei, C Chen… - Oncogene, 2021 - nature.com
Metastasis is the fundamental cause of cancer mortality, but there are still very few anti-metastatic
drugs available. Endosomal trafficking has been implicated in tumor metastasis, and …
drugs available. Endosomal trafficking has been implicated in tumor metastasis, and …
The temporal association of CapZ with early endosomes regulates endosomal trafficking and viral entry into host cells
Background Many viruses enter host cells by hijacking endosomal trafficking. CapZ, a
canonical actin capping protein, participates in endosomal trafficking, yet its precise role in …
canonical actin capping protein, participates in endosomal trafficking, yet its precise role in …
VCP/p97 targets the nuclear export and degradation of p27Kip1 during G1 to S phase transition
One of the critical regulatory mechanisms for cell cycle progression is the timely degradation
of CDK inhibitors, including p21 Cip1 and p27 Kip1 . VCP/p97, an AAA‐ATPase, is reported …
of CDK inhibitors, including p21 Cip1 and p27 Kip1 . VCP/p97, an AAA‐ATPase, is reported …