Aromatase inhibitor treatment of breast cancer cells increases the expression of let‐7f, a microRNA targeting CYP19A1
Y Shibahara, Y Miki, Y Onodera, S Hata… - The Journal of …, 2012 - Wiley Online Library
Aromatase inhibitors (AIs) are considered the gold standard of endocrine therapy for oestrogen
receptor‐positive postmenopausal breast cancer patients. AI treatment was reported to …
receptor‐positive postmenopausal breast cancer patients. AI treatment was reported to …
Runx2 in human breast carcinoma: its potential roles in cancer progression
Y Onodera, Y Miki, T Suzuki, K Takagi… - Cancer …, 2010 - Wiley Online Library
Runx2 has been proposed as one of the pivotal factors in the process of osteogenesis and
metastasis in human malignancies including breast cancer, but its details have not been …
metastasis in human malignancies including breast cancer, but its details have not been …
Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers
…, Z Liu, N Ota, H Kitamura, Y Onodera… - Nature …, 2020 - nature.com
Transcriptional dysregulation, which can be caused by genetic and epigenetic alterations, is
a fundamental feature of many cancers. A key cytoprotective transcriptional activator, NRF2, …
a fundamental feature of many cancers. A key cytoprotective transcriptional activator, NRF2, …
NRF2 immunolocalization in human breast cancer patients as a prognostic factor
Y Onodera, H Motohashi, K Takagi… - Endocrine-related …, 2014 - erc.bioscientifica.com
Interleukin-6 (IL-6) is suggested to have a pathogenic role in the progression of prostate
cancer (PC), therefore representing an attractive target for new therapies. However, due to the …
cancer (PC), therefore representing an attractive target for new therapies. However, due to the …
[PDF][PDF] Increased intratumoral androgens in human breast carcinoma following aromatase inhibitor exemestane treatment
…, S Nagasaki, H Hirakawa, Y Onodera… - Endocrine-related …, 2010 - hormonebalance.org
Sex steroids play important roles in the development of many human breast carcinomas,
and aromatase inhibitors are used for the anti-estrogen therapy. Recent studies have …
and aromatase inhibitors are used for the anti-estrogen therapy. Recent studies have …
Nucleobindin 2 in human breast carcinoma as a potent prognostic factor
S Suzuki, K Takagi, Y Miki, Y Onodera… - Cancer …, 2012 - Wiley Online Library
It is well‐known that estrogens immensely contribute to the progression of human breast
carcinoma, but their detailed molecular mechanisms remain largely unclear. In this study, we …
carcinoma, but their detailed molecular mechanisms remain largely unclear. In this study, we …
IL-11 contribution to tumorigenesis in an NRF2 addiction cancer model
H Kitamura, Y Onodera, S Murakami, T Suzuki… - Oncogene, 2017 - nature.com
The interaction between cancer cells and their microenvironment is an important determinant
of the pathological nature of cancers, particularly their tumorigenic abilities. The KEAP1-…
of the pathological nature of cancers, particularly their tumorigenic abilities. The KEAP1-…
Therapeutic efficacy of transcranial magnetic stimulation for hereditary spinocerebellar degeneration
…, T Tsuda, Y Shiga, K Miyazawa, Y Onodera… - The Tohoku journal of …, 1999 - jstage.jst.go.jp
We applied transcranial magnetic stimulation (TMS) as a therapeutic approach for patients
with spinocerebellar degeneration (SCD). The subjects were four familial SCD patients (three …
with spinocerebellar degeneration (SCD). The subjects were four familial SCD patients (three …
OLFM 4, LY 6D and S100A7 as potent markers for distant metastasis in estrogen receptor‐positive breast carcinoma
…, K Takagi, H Suzuki, A Sato, Y Onodera… - Cancer …, 2018 - Wiley Online Library
Metastatic breast cancer is a highly lethal disease, and it is very important to evaluate the
biomarkers associated with distant metastasis. However, molecular features of distant …
biomarkers associated with distant metastasis. However, molecular features of distant …
KLF15 in breast cancer: a novel tumor suppressor?
T Yoda, KM McNamara, Y Miki, Y Onodera, K Takagi… - Cellular Oncology, 2015 - Springer
Purpose Krüppel-like factor 15 (KLF15) is a transcription factor that is involved in various
biological processes, including cellular proliferation, differentiation and death. In addition, …
biological processes, including cellular proliferation, differentiation and death. In addition, …