User profiles for Wang Tian

Tian-Li Wang

Professor of Pathology, Oncology, and Gynecology/Obstetrics, Johns Hopkins University
Verified email at jhmi.edu
Cited by 38821

Diagnosis and treatment recommendations for pediatric respiratory infection caused by the 2019 novel coronavirus

…, R Lin, LF Tang, TL Wang, W Wang, YS Wang… - World journal of …, 2020 - Springer
Since December 2019, an epidemic caused by novel coronavirus (2019-nCoV) infection
has occurred unexpectedly in China. As of 8 pm, 31 January 2020, more than 20 pediatric …

[HTML][HTML] Bioactive flavonoids in medicinal plants: Structure, activity and biological fate

T Wang, Q Li, K Bi - Asian journal of pharmaceutical sciences, 2018 - Elsevier
Flavonoids, a class of polyphenol secondary metabolites, are presented broadly in plants
and diets. They are believed to have various bioactive effects including anti-viral, anti-…

Notch signaling, γ-secretase inhibitors, and cancer therapy

IM Shih, TL Wang - Cancer research, 2007 - AACR
The Notch signaling pathway represents a critical component in the molecular circuits that
control cell fate during development. Aberrant activation of this pathway contributes to …

Detection of circulating tumor DNA in early-and late-stage human malignancies

…, Y Wang, N Agrawal, BR Bartlett, H Wang… - Science translational …, 2014 - science.org
The development of noninvasive methods to detect and monitor tumors continues to be a
major challenge in oncology. We used digital polymerase chain reaction–based technologies …

Detection and localization of surgically resectable cancers with a multi-analyte blood test

JD Cohen, L Li, Y Wang, C Thoburn, B Afsari… - Science, 2018 - science.org
Earlier detection is key to reducing cancer deaths. Here, we describe a blood test that can
detect eight common cancer types through assessment of the levels of circulating proteins and …

Cutting edge: 1, 25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression

TT Wang, FP Nestel, V Bourdeau, Y Nagai… - The Journal of …, 2004 - journals.aai.org
The hormonal form of vitamin D 3, 1, 25-dihydroxyvitamin D 3 (1, 25 (OH) 2 D 3), is an immune
system modulator and induces expression of the TLR coreceptor CD14. 1, 25 (OH) 2 D 3 …

Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma

S Jones, TL Wang, IM Shih, TL Mao, K Nakayama… - Science, 2010 - science.org
Ovarian clear cell carcinoma (OCCC) is an aggressive human cancer that is generally resistant
to therapy. To explore the genetic origin of OCCC, we determined the exomic sequences …

[HTML][HTML] A long noncoding RNA activated by TGF-β promotes the invasion-metastasis cascade in hepatocellular carcinoma

…, F Liu, W Pan, T Wang, C Zhou, S Wang, Y Wang… - Cancer cell, 2014 - cell.com
The role of TGF-β-induced epithelial-mesenchymal transition (EMT) in cancer cell dissemination
is well established, but the involvement of lncRNAs in TGF-β signaling is still unknown. …

An integrated space-to-ground quantum communication network over 4,600 kilometres

…, CY Lu, R Shu, JY Wang, L Li, NL Liu, F Xu, XB Wang… - Nature, 2021 - nature.com
Quantum key distribution (QKD) 1 , 2 has the potential to enable secure communication and
information transfer 3 . In the laboratory, the feasibility of point-to-point QKD is evident from …

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

…, VE Velculescu, TL Wang… - Proceedings of the …, 2013 - National Acad Sciences
Malignant cells, like all actively growing cells, must maintain their telomeres, but genetic
mechanisms responsible for telomere maintenance in tumors have only recently been …