Differentiation of adult stem cells derived from bone marrow stroma into Leydig or adrenocortical cells
T Yazawa, T Mizutani, K Yamada, H Kawata… - …, 2006 - academic.oup.com
Adult stem cells from bone marrow, referred to as mesenchymal stem cells or marrow
stromal cells (MSCs), are defined as pluripotent cells and have the ability to differentiate into …
stromal cells (MSCs), are defined as pluripotent cells and have the ability to differentiate into …
Cyp11b1 is induced in the murine gonad by luteinizing hormone/human chorionic gonadotropin and involved in the production of 11-ketotestosterone, a major fish …
T Yazawa, M Uesaka, Y Inaoka, T Mizutani… - …, 2008 - academic.oup.com
We have shown previously that Cyp11b1, an 11β-hydroxylase responsible for glucocorticoid
biosynthesis in the adrenal gland, was induced by cAMP in androgen-producing Leydig-…
biosynthesis in the adrenal gland, was induced by cAMP in androgen-producing Leydig-…
High temperature causes masculinization of genetically female medaka by elevation of cortisol
…, T Yamaguchi, E Shiraishi, T Yazawa… - Molecular …, 2010 - Wiley Online Library
In poikilothermic vertebrates, sex determination is sometimes influenced by environmental
factors such as temperature. However, little is known about the molecular mechanisms …
factors such as temperature. However, little is known about the molecular mechanisms …
Cortisol is involved in temperature-dependent sex determination in the Japanese flounder
T Yamaguchi, N Yoshinaga, T Yazawa, K Gen… - …, 2010 - academic.oup.com
In vertebrates, sex is normally determined by genotype. However, in poikilothermal vertebrates,
including reptiles, amphibians, and fishes, sex determination is greatly influenced by …
including reptiles, amphibians, and fishes, sex determination is greatly influenced by …
PPAR-γ coactivator-1α regulates progesterone production in ovarian granulosa cells with SF-1 and LRH-1
T Yazawa, Y Inaoka, R Okada, T Mizutani… - Molecular …, 2010 - academic.oup.com
Previously, we demonstrated that bone marrow-derived mesenchymal stem cells (MSCs)
differentiate into steroidogenic cells such as Leydig and adrenocortical cells by the introduction …
differentiate into steroidogenic cells such as Leydig and adrenocortical cells by the introduction …
Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor
…, K Yamada, Z Shou, T Mizutani, T Yazawa… - Biochemical …, 2003 - portlandpress.com
Zinc-fingers and homeoboxes (ZHX) 1 is a transcription factor that interacts with the activation
domain of the A subunit of nuclear factor-Y (NF-YA). Using a yeast two-hybrid system, a …
domain of the A subunit of nuclear factor-Y (NF-YA). Using a yeast two-hybrid system, a …
11-ketotestosterone is a major androgen produced in human gonads
…, A Umezawa, K Miyamoto, T Yazawa - The Journal of …, 2016 - academic.oup.com
Context: 11-ketotestosterone (11-KT) is a novel class of active androgen. However, the detail
of its synthesis remains unknown for humans. Objective: The objective of this study was to …
of its synthesis remains unknown for humans. Objective: The objective of this study was to …
Incidence and outcome of osteoporotic fractures in 2004 in Sado City, Niigata Prefecture, Japan
…, N Endo, T Oinuma, E Endo, T Yazawa… - Journal of bone and …, 2008 - Springer
Osteoporotic fracture in elderly populations is increasing worldwide, but there are few data
on the incidence and outcome of osteoporotic fractures, including upper extremity and …
on the incidence and outcome of osteoporotic fractures, including upper extremity and …
Liver receptor homolog-1 regulates the transcription of steroidogenic enzymes and induces the differentiation of mesenchymal stem cells into steroidogenic cells
T Yazawa, Y Inanoka, T Mizutani, M Kuribayashi… - …, 2009 - academic.oup.com
Steroidogenic factor-1 (SF-1, also known as Ad4BP) has been demonstrated to be a primary
transcriptional regulator of steroidogenic-related genes. However, mRNA for liver receptor …
transcriptional regulator of steroidogenic-related genes. However, mRNA for liver receptor …
Design and test results of 6.6 kV high-Tc superconducting fault current limiter
T Yazawa, E Yoneda, J Matsuzaki… - IEEE transactions on …, 2001 - ieeexplore.ieee.org
A 6.6 kV single-phase fault current limiter (FCL) using a high-Tc superconducting coil as a
limiting coil was developed. The development is a preliminary step to investigate the feasibility …
limiting coil was developed. The development is a preliminary step to investigate the feasibility …