Although immune-checkpoint inhibitors (ICIs) have been a remarkable advancement in bladder
cancer treatment, the response rate to single-agent ICIs remains suboptimal. There has …

The combination of targeted therapy with immune checkpoint inhibition (ICI) is an area of
intense interest. We studied the interaction of fibroblast growth factor receptor (FGFR) inhibition …

High-grade urothelial cancer contains intrinsic molecular subtypes that exhibit differences in
underlying tumor biology and can be divided into luminal-like and basal-like subtypes. We …

Background Although the perioperative management of patients with pheochromocytoma
has been improving recently, severe hypotensive episodes can occur that require …

The major adrenal tumors with endocrine activity are primary aldosteronism, Cushing's
syndrome/mild autonomous cortisol secretion, and pheochromocytoma/paraganglioma. …

BACKGROUND: Primary aldosteronism caused by aldosterone-producing adenoma is the
most common curable cause of secondary hypertension, but despite resection, many patients …

The aim of this retrospective study was to identify clinical predictors of early biochemical
recurrence (BCR) in patients with high-risk prostate cancer (PCa) treated with carbon-ion …

Background Primary aldosteronism is the most common curable cause of secondary
hypertension. Despite resection, however, many patients with primary aldosteronism continue to …

Fork-head box protein A1 (FOXA1) is a “pioneer factor” that is known to bind to the androgen
receptor (AR) and regulate the transcription of AR-specific genes. However, the precise role …

Objective Correct interpretation of renal function in patients with primary aldosteronism is
difficult before adrenalectomy, because subtle kidney impairment is often masked by …