Microorganisms can switch from a planktonic, free-swimming life-style to a sessile, colonial
state, called a biofilm, which confers resistance to environmental stress. Conversion between …

Vibrio cholerae, the causative agent of cholera, is a facultative human pathogen with
intestinal and aquatic life cycles. The capacity of V. cholerae to recognize and respond to …

Cyclic di‐guanylic acid (c‐diGMP) is a second messenger that modulates the cell surface
properties of several microorganisms. Concentrations of c‐diGMP in the cell are controlled by …

Vibrio cholerae is a motile bacterium responsible for the disease cholera, and motility has
been hypothesized to be inversely regulated with virulence. We examined the transcription …

Vibrio cholerae undergoes phenotypic variation that generates two morphologically different
variants, termed smooth and rugose. The transcriptional profiles of the two variants differ …

Indole has been proposed to act as an extracellular signal molecule influencing biofilm
formation in a range of bacteria. For this study, the role of indole in Vibrio cholerae biofilm …

Microbiome research has increased dramatically in recent years, driven by advances in
technology and significant reductions in the cost of analysis. Such research has unlocked a …

Microorganisms use phase variation to increase population diversity to maximize evolutionary
success. One such variation is the smooth to rugose phenotype change in Vibrio cholerae…

Survival at host temperature is a critical trait for pathogenic microbes of humans. Thermally
dimorphic fungal pathogens, including Histoplasma capsulatum, are soil fungi that undergo …

Vibrio cholerae, the causative agent of the disease cholera, can generate rugose variants
that have an increased capacity to form biofilms. Rugosity and biofilm formation are critical for …