Background The prognosis for patients with relapsed or refractory diffuse large B-cell lymphoma
(DLBCL) is poor. Glofitamab is a bispecific antibody that recruits T cells to tumor cells. …

Transparent and electrically conductive composite silica films were fabricated on glass and
hydrophilic SiO x /silicon substrates by incorporation of individual graphene oxide sheets into …

Background First-line durvalumab plus etoposide with either cisplatin or carboplatin (platinum–etoposide)
showed a significant improvement in overall survival versus platinum–…

The spread of multidrug-resistant Staphylococcus aureus (MRSA) strains in the clinical
environment has begun to pose serious limits to treatment options. Yet virtually nothing is known …

Recent advances in diagnosis and treatment are enabling a more targeted approach to
treating lung cancers. Therapy targeting the specific oncogenic driver mutation could inhibit …

Somatic mutation of the AML1/RUNX1(RUNX1) gene is seen in acute myeloid leukemia (AML)
M0 subtype and in AML transformed from myelodysplastic syndrome, but the impact of …

The studies concerning clinical implications of TET2 mutation in patients with primary acute
myeloid leukemia (AML) are scarce. We analyzed TET2 mutation in 486 adult patients with …

Purpose: Clinical reports about responsiveness to gefitinib treatment in patients of non-small
cell lung cancer (NSCLC) with mutations in exon 20 of epidermal growth factor receptor (…

DNMT3A mutations are associated with poor prognosis in acute myeloid leukemia (AML), but
the stability of this mutation during the clinical course remains unclear. In the present study …

Mutations in the additional sex comb-like 1 (ASXL1) gene were recently shown in various
myeloid malignancies, but they have not been comprehensively investigated in acute myeloid …