The analysis of polymorphism data is becoming increasingly important as a complementary
tool to classical genetic analyses. Nevertheless, despite plunging sequencing costs, …

Evolve and resequence (E&R) is a new approach to investigate the genomic responses to
selection during experimental evolution. By using whole genome sequencing of pools of …

Recent statistical analyses suggest that sequencing of pooled samples provides a cost effective
approach to determine genome-wide population genetic parameters. Here we introduce …

The genetic architecture of adaptive traits is of key importance to predict evolutionary
responses. Most adaptive traits are polygenic—ie, result from selection on a large number of …

Global climate change (GCC) increasingly threatens biodiversity through the loss of species,
and the transformation of entire ecosystems. Many species are challenged by the pace of …

Sequencing pooled DNA samples (Pool-Seq) is the most cost-effective approach for the
genome-wide comparison of population samples. Here, we introduce PoPoolation2, the first …

Understanding the genetic underpinnings of adaptive change is a fundamental but largely
unresolved problem in evolutionary biology. D rosophila melanogaster, an ancestrally tropical …

SciRoKo is a user-friendly software tool for the identification of microsatellites in genomic
sequences. The combination of an extremely fast search algorithm with a built-in summary …

Transposable elements (TEs) are mobile genetic elements that parasitize genomes by semi-autonomously
increasing their own copy number within the host genome. While TEs are …

The P-element is one of the best understood eukaryotic transposable elements. It invaded
Drosophila melanogaster populations within a few decades but was thought to be absent from …