Advanced machine learning model for predicting Crohn's disease with enhanced ant colony optimization

X He, H Ye, R Zhao, M Lu, Q Chen, L Bao, T Lv… - Computers in Biology …, 2023 - Elsevier
Abstract Changes in human lifestyles have led to a dramatic increase in the incidence of
Crohn's disease worldwide. Predicting the activity and remission of Crohn's disease has …

The enrichment of the gut microbiota Lachnoclostridium is associated with the presence of intratumoral tertiary lymphoid structures in hepatocellular carcinoma

…, L Hu, K Huang, Q Chen, J Yao, G Lin, L Bao… - Frontiers in …, 2023 - frontiersin.org
Backgrounds and aims Immunotherapies have formed an entirely new treatment paradigm
for hepatocellular carcinoma (HCC). Tertiary lymphoid structure (TLS) has been associated …

Reducing moisture effects on soil organic carbon content prediction in visible and near-infrared spectra with an external parameter othogonalization algorithm

Y Cao, N Bao, S Liu, W Zhao… - Canadian Journal of Soil …, 2020 - cdnsciencepub.com
Field spectroscopy and other efficient hyperspectral techniques have been widely used to
measure soil properties, including soil organic carbon (SOC) content. However, reflectance …

ADMET evaluation in drug discovery: 21. Application and industrial validation of machine learning algorithms for Caco-2 permeability prediction

D Wang, J Jin, G Shi, J Bao, Z Wang, S Li… - Journal of …, 2025 - Springer
The Caco-2 cell model has been widely used to assess the intestinal permeability of drug
candidates in vitro, owing to its morphological and functional similarity to human enterocytes. …

Highly efficient extraction separation of uranium (VI) and thorium (IV) from nitric acid solution with di (1-methyl-heptyl) methyl phosphonate

M Tan, C Huang, S Ding, F Li, Q Li, L Zhang… - Separation and …, 2015 - Elsevier
The extraction behaviors of U(VI) and Th(IV), as well as the extraction of HNO 3 were
investigated by using di(1-methyl-heptyl) methyl phosphonate (DMHMP) as an extractant and …

Preparation and application of mouse monoclonal antibodies against human cyclophilin A (CypA)

L Qiao, X Hong, S Li, C He, S Gao… - Xi bao yu fen zi Mian yi …, 2018 - europepmc.org
Objective To prepare monoclonal antibodies against human cyclophilin A (CypA) and explore
the role of CypA in the occurrence and development of colon cancer. Methods According …

A Survey on Evolutionary Computation for Identifying Biomarkers of Complex Disease

J Liang, Z Hu, Y Bi, H Cheng, K Yu… - IEEE Transactions …, 2024 - ieeexplore.ieee.org
Biological markers (ie, biomarkers) is the key to predicting disease states and revealing the
molecular mechanisms in precision medicine of complex disease (eg, cancer). With the …

Intrauterine growth restriction alters nutrient metabolism in the intestine of porcine offspring

T Li, S Huang, L Lei, S Tao, Y Xiong, G Wu, J Hu… - Journal of animal …, 2021 - Springer
Background Intrauterine growth restriction (IUGR) has negative impacts on the postnatal
survival, growth and development of humans and animals, with not only on newborns but also …

Design for excellence (DfX) for high-rise modular buildings: from DfX considerations to module design guidelines using the case of Hong Kong

V Laovisutthichai, W Lu, SP Low - Architectural Engineering and …, 2024 - Taylor & Francis
ABSTRACT Design for excellence (DfX) presents a significant opportunity for early design
to ensure the efficiency and buildability of high-rise modular buildings and realize their …

R-is superior to S-form of α-lipoic acid in anti-inflammatory and antioxidant effects in laying hens

Q Liu, W Li, S Huang, L Zhao, J Zhang, C Ji, Q Ma - Antioxidants, 2022 - mdpi.com
The development of single enantiomers with high efficiency and low toxic activity has become
a hot spot for the development and application of drugs and active additives. The aim of …