User profiles for Katherine M. Kichula
 | Katherine M KichulaDoctoral Candidate, University of Colorado Verified email at cuanschutz.edu Cited by 100 |
HLA and KIR genetic association and NK cells in anti-NMDAR encephalitis
…, T Kanbayashi, NR Pollock, KM Kichula… - Frontiers in …, 2024 - frontiersin.org
Introduction Genetic predisposition to autoimmune encephalitis with antibodies against N-methyl-D-aspartate
receptor (NMDAR) is poorly understood. Given the diversity of associated …
receptor (NMDAR) is poorly understood. Given the diversity of associated …
Complete sequences of six major histocompatibility complex haplotypes, including all the major MHC class II structures
…, S Scholz, NR Pollock, WH Palmer, KM Kichula… - Hla, 2023 - Wiley Online Library
Accurate and comprehensive immunogenetic reference panels are key to the successful
implementation of population‐scale immunogenomics. The 5Mbp Major Histocompatibility …
implementation of population‐scale immunogenomics. The 5Mbp Major Histocompatibility …
The combinatorial diversity of KIR and HLA class I allotypes in Peninsular Malaysia
Killer cell immunoglobulin‐like receptors (KIRs) interact with polymorphic human leucocyte
antigen (HLA) class I molecules, modulating natural killer (NK) cell functions and affecting …
antigen (HLA) class I molecules, modulating natural killer (NK) cell functions and affecting …
Conservation, extensive heterozygosity, and convergence of signaling potential all indicate a critical role for KIR3DL3 in higher primates
Natural killer (NK) cell functions are modulated by polymorphic killer cell immunoglobulin-like
receptors (KIR). Among 13 human KIR genes, which vary by presence and copy number, …
receptors (KIR). Among 13 human KIR genes, which vary by presence and copy number, …
[HTML][HTML] An archaic HLA class I receptor allele diversifies natural killer cell-driven immunity in First Nations peoples of Oceania
…, SC Wong, J Widjaja, EB Clemens, S Zhu, KM Kichula… - Cell, 2024 - cell.com
Genetic variation in host immunity impacts the disproportionate burden of infectious diseases
that can be experienced by First Nations peoples. Polymorphic human leukocyte antigen (…
that can be experienced by First Nations peoples. Polymorphic human leukocyte antigen (…
High-Resolution Analysis Identifies High Frequency of KIR-A Haplotypes and Inhibitory Interactions of KIR With HLA Class I in Zhejiang Han
S Tao, Y He, KM Kichula, J Wang, J He… - Frontiers in …, 2021 - frontiersin.org
Killer cell immunoglobulin-like receptors (KIR) interact with human leukocyte antigen (HLA)
class I molecules, modulating critical NK cell functions in the maintenance of human health. …
class I molecules, modulating critical NK cell functions in the maintenance of human health. …
Allelic variation of KIR and HLA tunes the cytolytic payload and determines functional hierarchy of NK cell repertoires
…, D Clement, A Haroun-Izquierdo, KM Kichula… - Blood …, 2023 - ashpublications.org
The functionality of natural killer (NK) cells is tuned during education and is associated with
remodeling of the lysosomal compartment. We hypothesized that genetic variation in killer …
remodeling of the lysosomal compartment. We hypothesized that genetic variation in killer …
HLA‐DPB1*13:01 associates with enhanced, and KIR2DS4*001 with diminished protection from developing severe COVID‐19
Extreme polymorphism of HLA and killer‐cell immunoglobulin‐like receptors (KIR) differentiates
immune responses across individuals. Additional to T cell receptor interactions, subsets …
immune responses across individuals. Additional to T cell receptor interactions, subsets …
Allele imputation for the killer cell immunoglobulin-like receptor KIR3DL1/S1
…, LA Leaton, EA Harrison, KM Kichula… - PLoS Computational …, 2022 - journals.plos.org
Highly polymorphic interaction of KIR3DL1 and KIR3DS1 with HLA class I ligands
modulates the effector functions of natural killer (NK) cells and some T cells. This genetically …
modulates the effector functions of natural killer (NK) cells and some T cells. This genetically …
Exceptional diversity of KIR and HLA class I in Egypt
G Montero‐Martin, KM Kichula, MK Misra… - HLA, 2024 - Wiley Online Library
Genetically determined variation of killer cell immunoglobulin like receptors (KIR) and their
HLA class I ligands affects multiple aspects of human health. Their extreme diversity is …
HLA class I ligands affects multiple aspects of human health. Their extreme diversity is …