[HTML][HTML] EBV latent membrane protein 1 augments γδ T cell cytotoxicity against nasopharyngeal carcinoma by induction of butyrophilin molecules

Y Liu, KS Lui, Z Ye, TY Fung, L Chen, PY Sit… - Theranostics, 2023 - ncbi.nlm.nih.gov
Nasopharyngeal carcinoma (NPC) is a diverse cancer with no well-defined tumor antigen,
associated with oncogenic Epstein-Barr Virus (EBV), and with usually late-stage diagnosis …

Anti-PD1 does not improve pyroptosis induced by γδ T cells but promotes tumor regression in a pleural mesothelioma mouse model

KS Lui, Z Ye, HC Chan, Y Tanaka… - Frontiers in …, 2023 - frontiersin.org
Introduction Mesothelioma is an aggressive tumor in the pleural cavity that is difficult to treat.
Diagnosis is usually late with minimal treatment options available for the patients and with …

[HTML][HTML] Epstein–Barr Virus BRRF1 Induces Butyrophilin 2A1 in Nasopharyngeal Carcinoma NPC43 Cells via the IL-22/JAK3-STAT3 Pathway

Y Liu, KS Lui, Z Ye, L Chen, AKL Cheung - International Journal of …, 2024 - mdpi.com
Epstein–Barr virus is highly associated with nasopharyngeal carcinoma (NPC) with genes
expressed for tumor transformation or maintenance of viral latency, but there are certain …

[PDF][PDF] Investigating Combined Gamma-delta T Cells and Immune Checkpoint Therapy Against Mesothelioma Via Pyroptosis in Vivo

KS LUI - 2023 - scholars.hkbu.edu.hk
Mesothelioma, a life-threatening cancer affecting the mesothelial lining of the pleura, peritoneum,
and pericardium, poses significant treatment challenges. Primarily caused by asbestos …

[HTML][HTML] Organoid models of breathing disorders reveal patterning defect of hindbrain neurons caused by PHOX2B-PARMs

KNC Lui, Z Li, FPL Lai, ST Lau, ESW Ngan - Stem Cell Reports, 2023 - cell.com
Retrotrapezoid nucleus (RTN) neurons in the brainstem regulate the ventilatory response to
hypercarbia. It is unclear how PHOX2B-polyalanine repeat mutations (PHOX2B-PARMs) …

Recurrent natural killer cell lymphoma with central nervous system metastasis mimicking cerebellar infarction

L Li, GK Leung, RS Ho, W Lui - World Neurosurgery, 2015 - Elsevier
Background Natural killer cell lymphoma is an uncommon hematologic malignancy, and
central nervous system metastasis is rare. The classic magnetic resonance imaging …

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype …

…, V Wong, PW Ng, CHT Lui, NC Sin… - Pharmacogenetics …, 2008 - journals.lww.com
Objectives Many antiepileptic drugs (AEDs) prevent seizures by blocking voltage-gated brain
sodium channels. However, treatment is ineffective in 30% of epilepsy patients, which might…

Viral clearance and inflammatory response patterns in adults hospitalized for pandemic 2009 influenza A (H1N1) virus pneumonia

…, MCW Chan, BCK Wong, GCY Lui, WWY Sin… - Antiviral …, 2011 - journals.sagepub.com
Background Little is known about the virological and inflammatory responses of severe
pandemic 2009 influenza A(H1N1) virus pneumonia during antiviral treatment. Methods In a …

HMGB1/RAGE signaling and pro-inflammatory cytokine responses in non-HIV adults with active pulmonary tuberculosis

G Lui, CK Wong, M Ip, YJ Chu, IMH Yung… - PLoS …, 2016 - journals.plos.org
Background We aimed to study the pathogenic roles of High-Mobility Group Box 1 (HMGB1)
/ Receptor-for-Advanced-Glycation-End-products (RAGE) signaling and pro-inflammatory …

Gene-Wide Tagging Study Of Association Between ABCB1 Polymorphisms and Multidrug Resistance in Epilepsy in Han Chinese

P Kwan, V Wong, PW Ng, CHT Lui, NC Sin… - …, 2009 - Taylor & Francis
Aims: It remains controversial whether polymorphisms of the multidrug resistance gene
ABCB1 are associated with pharmacoresistance in epilepsy. To further study the potential …