Renal ischemia reperfusion injury (IRI), a common event after renal transplantation, causes
acute kidney injury (AKI), increases the risk of delayed graft function (DGF), primes the donor …

Necrosis is the predominant form of regulated cell death in acute kidney injury (AKI) and
represents results in the formation of casts that appear in the urine sedimentation, referred to as …

Background Histopathological assessment of transplant biopsies is currently the standard
method to diagnose allograft rejection and can help guide patient management, but it is one of …

Background The development of deep neural networks is facilitating more advanced digital
analysis of histopathologic images. We trained a convolutional neural network for multiclass …

Tissues and biofluids are important sources of information used for the detection of diseases
and decisions on patient therapies. There are several accepted methods for preservation of …

Accumulating evidence demonstrates important roles for metabolism in cell fate determination.
However, it is a challenge to assess metabolism at a spatial resolution that acknowledges …

Systemic sclerosis (SSc) is an autoimmune fibrotic disease whose pathogenesis is poorly
understood and lacks effective therapies. We undertook quantitative analyses of T cell …

The performance of deep learning applications in digital histopathology can deteriorate
significantly due to staining variations across centers. We employ cycle-consistent generative …

Background IgG 4 -related disease (IgG 4 -RD) is an immune-mediated fibrotic disorder that
has been linked to CD4 + cytotoxic T lymphocytes (CD4 + CTLs). The effector phenotype of …

The XVIth Banff Meeting for Allograft Pathology was held in Banff, Alberta, Canada, from
September 19 to 23, 2022, as a joint meeting with the Canadian Society of Transplantation. In …