User profiles for Hafiz Muzzammel Rehman

Hafiz Muzzammel Rehman

University of the Punjab
Verified email at pu.edu.pk
Cited by 465

A putative prophylactic solution for COVID-19: development of novel multiepitope vaccine candidate against SARS-COV-2 by comprehensive immunoinformatic and …

HM Rehman, MU Mirza, MA Ahmad, M Saleem… - Biology, 2020 - mdpi.com
Simple Summary COVID-19, caused by a novel coronavirus, SARS-CoV-2, first emerged in
China in December 2019, and then spread around the globe with more than 29 million …

Rational design of novel potential EGFR inhibitors by 3D-QSAR, molecular docking, molecular dynamics simulation, and pharmacokinetics studies

…, Y Moukhliss, H Hajji, HM Rehman… - Chemical Data …, 2022 - Elsevier
The epidermal growth factor receptor (EGFR) is one of the most attractive drug targets against
the human pancreas cancer cell line (Panc-1). In this research, forty xanthine derivatives …

National prevalence rate of hepatitis B and C in Pakistan and its risk factors

…, H Raza, F Abid, N Saeed, HM Rehman… - Journal of Public …, 2020 - Springer
Aim The purpose of this review was to reveal the prevalence rate of viral hepatitis in Pakistan
and diverse risk factors that are associated with infections. The distribution of the genotype …

Identification of RdRp inhibitors against SARS-CoV-2 through E-pharmacophore-based virtual screening, molecular docking and MD simulations approaches

HM Rehman, M Sajjad, MA Ali, R Gul, M Naveed… - International Journal of …, 2023 - Elsevier
The outbreak of novel Coronavirus, an enduring pandemic declared by WHO, has
consequences to an alarming ongoing public health menace which has already claimed several …

Identification of NS2B-NS3 protease inhibitors for therapeutic application in ZIKV infection: A pharmacophore-based high-throughput virtual screening and MD …

HM Rehman, M Sajjad, MA Ali, R Gul, M Irfan… - Vaccines, 2023 - mdpi.com
Zika virus (ZIKV) pandemic and its implication in congenital malformations and severe
neurological disorders had created serious threats to global health. ZIKV is a mosquito-borne …

In silico investigation of a chimeric IL24-LK6 fusion protein as a potent candidate against breast cancer

H Muhammad Rehman, HM Rehman… - … and Biology Insights, 2023 - journals.sagepub.com
Targeted delivery of therapeutic anticancer chimeric molecules enhances the efficacy of drug
by improving cellular uptake and circulation time. Engineering the molecules to facilitate …

In Vitro Antidiabetic, Anti-Obesity and Antioxidant Analysis of Ocimum basilicum Aerial Biomass and in Silico Molecular Docking Simulations with Alpha-Amylase and …

ZI Noor, D Ahmed, HM Rehman, MT Qamar, M Froeyen… - Biology, 2019 - mdpi.com
The present study explored phytochemicals, porcine pancreatic α-amylase (PPA) and lipase
(PPL) inhibitory activities and antioxidant potential of polar and nonpolar extracts of the …

Optimizing the resveratrol fragments for novel in silico hepatocellular carcinoma de novo drug design

M Naveed, K Javed, T Aziz, A Abid, HM Rehman… - Scientific Reports, 2024 - nature.com
Hepatocellular carcinoma (HCC) incidence varies widely around the world and is impacted
by factors such as the prevalence of chronic hepatitis B and C infections, alcohol intake, and …

A computational investigation of galactopyranoside esters as antimicrobial agents through antiviral, molecular docking, molecular dynamics, pharmacokinetics, and …

MA Hosen, Y El Bakri, HM Rehman… - Journal of …, 2024 - Taylor & Francis
One of the most common viral infections worldwide is the Human Papilloma Virus (HPV) which
has been linked to cancer and other diseases in many countries. Monosaccharide esters …

Comprehensive Analysis and outcomes of hybridization of physiologically active heterocycles targeting epidermal growth factor receptor (EGFR)

M Kaur, HM Rehman, Y Wu, G Kaur… - Computers in Biology …, 2025 - Elsevier
Epidermal growth factor receptors (EGFR) are primarily engaged in the regulation of fundamental
cellular processes. Overexpression and mutations in these tyrosine kinases cause a …