Background Mitochondria provide most of the energy for brain cells by the process of
oxidative phosphorylation. Mitochondrial abnormalities and deficiencies in oxidative …

Mitochondrial deficiencies with unknown causes have been observed in schizophrenia (SZ)
and bipolar disorder (BD) in imaging and postmortem studies. Polymorphisms and somatic …

Albinism is a group of rare inherited disorders arising from impairment of melanin biosynthesis.
The reduction of melanin synthesis leads to hypopigmentation of the skin and eyes. A …

Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease characterized
by the death of upper and lower motor neurons. While causative genes have been …

Mood disorders and schizophrenia are common and complex disorders with consistent
evidence of genetic and environmental influences on predisposition. It is generally believed that …

A missense polymorphism in the NRG1 gene, Val > Leu in exon 11, was reported to increase
the risk of schizophrenia in selected families from the Central Valley region of Costa Rica (…

… Grammatikos, Alexandros; North Bristol NHS Trust Grigoriadou, Sofia; Barts Health NHS
Trust Jain, Rashmi; Oxford University Hospitals NHS Foundation Trust Lorenzo, Lorena; Barts …

Loss of pancreatic β cells is the hallmark of type 1 diabetes, for which provision of insulin is
the standard of care. While regenerative and stem cell therapies hold the promise of …

Background: As the primary burden of treating COVID-19 patients began to ease in the
United Kingdom, ophthalmology clinic volume within the National Health Service has since …

Background The purpose of this study was to examine the effects of glucose reduction stress
on lymphoblastic cell line (LCL) gene expression in subjects with schizophrenia compared …