Recent evidence suggests that complex karyotype (CK) defined by the presence of ≥3
chromosomal aberrations (structural and/or numerical) identified by using chromosome-banding …

We report on markedly different frequencies of genetic lesions within subsets of chronic
lymphocytic leukemia patients carrying mutated or unmutated stereotyped B-cell receptor …

The biological and clinical significance of a clonal B-cell lymphocytosis with an
immunophenotype consistent with marginal-zone origin (CBL-MZ) is poorly understood. We …

Chronic lymphocytic leukemia (CLL) patients with differential somatic hypermutation status
of the immunoglobulin heavy variable genes, namely mutated or unmutated, display …

Background The integration of Artificial Intelligence (AI) technology in cancer care has gained
unprecedented global attention over the past few decades. This has impacted the way that …

(1) Background: A proposed approach to promote periodontal tissue regeneration in cases of
peri-implantitis is the local administration of growth factors at the implant site. Recombinant …

Purpose: The role of antigen(s) in shaping the T-cell repertoire in chronic lymphocytic leukemia,
although relevant for understanding malignant cell interactions with cognate T cells, is …

Finding new ways to cost-effectively facilitate population screening and improve cancer
diagnoses at an early stage supported by data-driven AI models provides unprecedented …

The B cell receptor immunoglobulin (Ig) gene repertoires of marginal zone (MZ) lymphoproliferations
were analyzed in order to obtain insight into their ontogenetic relationships. Our …

Patients with chronic lymphocytic leukemia (CLL) harboring TP53 aberrations (TP53abs;
chromosome 17p deletion and/or TP53 mutation) exhibit an unfavorable clinical outcome. …