User profiles for Dong-Chan Oh

Dong-Chan Oh

Natural Products Research Institute, College of Pharmacy, Seoul National University
Verified email at snu.ac.kr
Cited by 10242

Dentigerumycin: a bacterial mediator of an ant-fungus symbiosis

DC Oh, M Poulsen, CR Currie, J Clardy - Nature Chemical Biology, 2009 - nature.com
Fungus-growing ants engage in mutualistic associations with both the fungus they cultivate
for food and actinobacteria (Pseudonocardia spp.) that produce selective antibiotics to …

Enhancement of proteasome activity by a small-molecule inhibitor of USP14

BH Lee, MJ Lee, S Park, DC Oh, S Elsasser, PC Chen… - Nature, 2010 - nature.com
Proteasomes, the primary mediators of ubiquitin–protein conjugate degradation, are
regulated through complex and poorly understood mechanisms. Here we show that USP14, a …

D-amino acids govern stationary phase cell wall remodeling in bacteria

H Lam, DC Oh, F Cava, CN Takacs, J Clardy… - Science, 2009 - science.org
In all known organisms, amino acids are predominantly thought to be synthesized and used
as their L-enantiomers. Here, we found that bacteria produce diverse D-amino acids as well, …

Common biosynthetic origins for polycyclic tetramate macrolactams from phylogenetically diverse bacteria

JAV Blodgett, DC Oh, S Cao… - Proceedings of the …, 2010 - National Acad Sciences
A combination of small molecule chemistry, biosynthetic analysis, and genome mining has
revealed the unexpected conservation of polycyclic tetramate macrolactam biosynthetic loci …

Nyuzenamide C, an Antiangiogenic Epoxy Cinnamic Acid-Containing Bicyclic Peptide from a Riverine Streptomyces sp.

…, SJ Nam, J Shin, SK Lee, YJ Yoon, DC Oh - Journal of Natural …, 2022 - ACS Publications
A new nonribosomal peptide, nyuzenamide C (1), was discovered from riverine sediment-derived
Streptomyces sp. DM14. Comprehensive analysis of the spectroscopic data of …

Bacterial protection of beetle-fungus mutualism

JJ Scott, DC Oh, MC Yuceer, KD Klepzig, J Clardy… - Science, 2008 - science.org
Host-microbe symbioses play a critical role in the evolution of biological diversity and
complexity. In a notably intricate system, southern pine beetles use symbiotic fungi to help …

Coculture of Marine Streptomyces sp. With Bacillus sp. Produces a New Piperazic Acid-Bearing Cyclic Peptide

…, K Moon, Y Kwon, M Bae, S Um, SK Lee, DC Oh - Frontiers in …, 2018 - frontiersin.org
Microbial culture conditions in the laboratory, which conventionally involve the cultivation of
one strain in one culture vessel, are vastly different from natural microbial environments. …

Species-Specific Secondary Metabolite Production in Marine Actinomycetes of the Genus Salinispora

PR Jensen, PG Williams, DC Oh… - Applied and …, 2007 - Am Soc Microbiol
Here we report associations between secondary metabolite production and phylogenetically
distinct but closely related marine actinomycete species belonging to the genus Salinispora…

Libertellenones A–D: Induction of cytotoxic diterpenoid biosynthesis by marine microbial competition

DC Oh, PR Jensen, CA Kauffman, W Fenical - Bioorganic & medicinal …, 2005 - Elsevier
The induction of biosynthesis of four new diterpenoids was observed following the addition
of a marine α-proteobacterium to an established culture of the marine-derived fungus …

Sceliphrolactam, a Polyene Macrocyclic Lactam from a Wasp-Associated Streptomyces sp.

DC Oh, M Poulsen, CR Currie, J Clardy - Organic letters, 2011 - ACS Publications
A previously unreported 26-membered polyene macrocyclic lactam, sceliphrolactam, was
isolated from an actinomycete, Streptomyces sp., associated with the mud dauber, Sceliphron …