Background The COVID-19 pandemic highlighted gaps in health surveillance systems, disease
prevention, and treatment globally. Among the many factors that might have led to these …

Background As set out in Sustainable Development Goal 3.3, the target date for ending the
HIV epidemic as a public health threat is 2030. Therefore, there is a crucial need to evaluate …

Tau, an intrinsically disordered neuronal protein and polyampholyte with an overall positive
charge, is a microtubule (MT) associated protein that binds to anionic domains of MTs and …

A current challenge in AI research is enabling AI systems to be inspired by external sources.
We present a method for subselecting portions of a training corpus based on relevance to …

Cross-Domain creative systems can learn how to creatively map and/or transform semantic
concepts from remote domains to their own. This project sets out to explore how a …

Chemistry, United States Military Academy, West Point, NY, USA. The autocatalytic aggregation
reaction of the misfolded 42-residue form of the amyloid-b peptide (Ab42) in the brain is …

Henry J. Lessen, Alexander J. Sodt. NICHD, National Institutes of Health, Bethesda, MD,
USA. Many biological processes rely on the induction of curvature and other bilayer …

Solvent accessibility of different parts of a protein or a molecular complex is an important
measure of its conformation and/or membrane insertion. While there are standard techniques …

Numerous cell signaling pathways depend on proteins that bind membrane surfaces with
conserved membrane targeting domains. The pleckstrin homology (PH) domain is the most …

Lipid droplets (LD) are intracellular organelles responsible for lipid storage, and they
emerge from the endoplasmic reticulum (ER) upon the accumulation of neutral lipids, mostly …