BACKGROUND & AIMS: This systematic review assesses findings of endoscopic surveys in
the general population with regard to gastroesophageal reflux disease (GERD). METHODS: …

Colorectal cancer (CRC) is a major cause of cancer mortality worldwide, however, the
molecular mechanisms underlying the pathogenesis of CRC remain largely unclear. Recent …

OBJECTIVES: Complications of peptic ulcer disease (PUD) are common in China.
Population-based estimates of the prevalence of PUD are needed to quantify and characterize the …

Colorectal cancer (CRC) is among the most common malignancies with limited treatments
other than surgery. The tumor microenvironment (TME) profiling enables the discovery of …

Fibrosis is a pathological feature of a variety of chronic inflammatory diseases that can affect
almost all organs, which can cause severe consequences and even lead to death. Fibrosis …

Microbiota-induced tumorigenesis is well established in solid tumors of the gastrointestinal
tract but rarely explored in hematologic malignancies. To determine the role of gut microbiota …

The overproduction of reactive oxygen species (ROS) is central to the progression of inflammatory
bowel disease (IBD), which may be the potential therapeutic target. Prussian blue (PB…

Although advances in spatial transcriptomics (ST) enlarge to unveil spatial landscape of
tissues, it remains challenging to delineate pathology-relevant and cellular localizations, and …

Intestinal fibrosis, a severe complication of Crohn’s disease (CD), is characterized by excessive
extracellular matrix (ECM) deposition and induces intestinal strictures, but there are no …

The overproduction of reactive oxygen species (ROS) is linked to inflammatory bowel disease
(IBD) and causes oxidative damage to DNA, proteins, and lipids. These ROS promote the …