Sustainable development: mainstream and critical perspectives

CJ Castro - Organization & Environment, 2004 - journals.sagepub.com
Like democracy and globalization, the concept of sustainable development has become
one of the most ubiquitous, contested, and indispensable concepts of our time. Although the …

[HTML][HTML] Dynamic Energy Return on Energy Investment (EROI) and material requirements in scenarios of global transition to renewable energies

I Capellán-Pérez, C De Castro, LJM González - Energy strategy reviews, 2019 - Elsevier
A novel methodology is developed to dynamically assess the energy and material investments
required over time to achieve the transition from fossil fuels to renewable energy sources …

A primer to scaffolded DNA origami

CE Castro, F Kilchherr, DN Kim, EL Shiao, T Wauer… - Nature …, 2011 - nature.com
Molecular self-assembly with scaffolded DNA origami enables building custom-shaped
nanometer-scale objects with molecular weights in the megadalton regime. Here we provide a …

Programmable motion of DNA origami mechanisms

…, L Zhou, HJ Su, CE Castro - Proceedings of the …, 2015 - National Acad Sciences
DNA origami enables the precise fabrication of nanoscale geometries. We demonstrate an
approach to engineer complex and reversible motion of nanoscale DNA origami machine …

The αβ T cell receptor is an anisotropic mechanosensor

…, K Takeuchi, ZYJ Sun, M Touma, CE Castro… - Journal of Biological …, 2009 - ASBMB
Thymus-derived lymphocytes protect mammalian hosts against virus- or cancer-related
cellular alterations through immune surveillance, eliminating diseased cells. In this process, T …

High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails

…, H Li, R Yu, D Wu, J Wolf, TG Martin, CE Castro… - Nature …, 2023 - nature.com
Enhancing CRISPR-mediated site-specific transgene insertion efficiency by homology-directed
repair (HDR) using high concentrations of double-stranded DNA (dsDNA) with Cas9 …

Mechanical design of DNA nanostructures

CE Castro, HJ Su, AE Marras, L Zhou, J Johnson - Nanoscale, 2015 - pubs.rsc.org
Structural DNA nanotechnology is a rapidly emerging field that has demonstrated great
potential for applications such as single molecule sensing, drug delivery, and templating …

Impairment of in vitro and in vivo heart function in angiotensin-(1-7) receptor MAS knockout mice

RAS Santos, CH Castro, E Gava, SVB Pinheiro… - …, 2006 - Am Heart Assoc
In this study we investigated the effects of the genetic deletion of the angiotensin (Ang)-(1-7)
receptor Mas on heart function. Localization of Mas in the mouse heart was evaluated by …

Daunorubicin‐loaded DNA origami nanostructures circumvent drug‐resistance mechanisms in a leukemia model

…, RA Patton, C Kural, DM Lucas, JC Byrd, CE Castro - Small, 2016 - Wiley Online Library
Many cancers show primary or acquired drug resistance due to the overexpression of efflux
pumps. A novel mechanism to circumvent this is to integrate drugs, such as anthracycline …

An architecture for making recommendations to courseware authors using association rule mining and collaborative filtering

E García, C Romero, S Ventura, C Castro - User Modeling and User …, 2009 - Springer
Nowadays we find more and more applications for data mining techniques in e-learning and
web-based adaptive educational systems. The useful information discovered can be used …