Urine sample analysis is irreplaceable as a non-invasive method for disease diagnosis and
follow-up. However, in urine samples, non-degraded protein and RNA may be only found in …

Bladder cancer is one of the most common cancers and, together with prostate carcinoma,
accounts for the majority of the malignancies of the genitourinary tract. Since prognosis …

Extracellular vesicles (EV) are emerging structures with promising properties for intercellular
communication. In addition, the characterization of EV in biofluids is an attractive source of …

Newly growing evidence highlights the essential role that epitranscriptomic marks play in
the development of many cancers; however, little is known about the role and implications of …

Cellular transformation and cancer progression is accompanied by changes in the metabolic
landscape. Master co-regulators of metabolism orchestrate the modulation of multiple …

Activation of the PTEN–PI3K–mTORC1 pathway consolidates metabolic programs that
sustain cancer cell growth and proliferation 1 , 2 . Here we show that mechanistic target of …

Urine contains extracellular vesicles (EVs) that concentrate molecules and protect them
from degradation. Thus, isolation and characterisation of urinary EVs could increase the …

… Author links open overlay panel Veronica Torrano 1 7 , Felix Royo 1 4 7 , Héctor Peinado 2
, Ana Loizaga-Iriarte 3 , Miguel Unda 3 , Juan M Falcón-Perez 1 4 5 , Arkaitz Carracedo 1 5 6 …

Simple Summary Renal cell carcinoma (RCC) is a heterogeneous and complex disease with
almost no response to chemotherapy. Immune checkpoint inhibitors have achieved great …

Urine extracellular vesicles are a valuable low-invasive source of information, especially for
the cells of the genitourinary tract. In the search for biomarkers, different techniques have …