User profiles for Aijun Lu

Aijun Lu

Pharmaron
Verified email at pharmaron-bj.com
Cited by 553

Discovery of GluN2A-selective NMDA receptor positive allosteric modulators (PAMs): tuning deactivation kinetics via structure-based design

…, E Villemure, RM Pastor, P Yuen, A Lu… - Journal of medicinal …, 2016 - ACS Publications
The N-methyl-d-aspartate receptor (NMDAR) is a Na + and Ca 2+ permeable ionotropic
glutamate receptor that is activated by the coagonists glycine and glutamate. NMDARs are …

Regional variation in components and antioxidant and antifungal activities of Perilla frutescens essential oils in China

J Tian, X Zeng, S Zhang, Y Wang, P Zhang, A Lü… - Industrial Crops and …, 2014 - Elsevier
Perilla frutescens is an important annual herb of the mint family that is native to East Asia,
particularly China, Korea, and Japan, is widely used as a fresh vegetable and in traditional …

iTRAQ analysis of gill proteins from the zebrafish (Danio rerio) infected with Aeromonas hydrophila

A Lü, X Hu, Y Wang, X Shen, X Li, A Zhu, J Tian… - Fish & shellfish …, 2014 - Elsevier
The gills are large mucosal surfaces and very important portals for pathogen entry in fish.
The aim of this study was to determine the gill immune response at the protein levels, the …

Gene expression profiling in the skin of zebrafish infected with Citrobacter freundii

A Lü, X Hu, J Xue, J Zhu, Y Wang, G Zhou - Fish & shellfish immunology, 2012 - Elsevier
Skin is considered the largest immunologically active organ, but its molecular mechanism
remains unclear in fish. Here, Affymetrix Zebrafish GeneChip was used to assess gene …

Single nucleotide polymorphisms in bovine PRL gene and their associations with milk production traits in Chinese Holsteins

A Lü, X Hu, H Chen, J Jiang, C Zhang, H Xu… - Molecular Biology …, 2010 - Springer
Prolactin (PRL) plays a crucial role in the initiation and maintenance of lactation in mammals.
In this study, seven PCR fragments representing most important functional domains of PRL …

Tetrahydrofuran-based transient receptor potential ankyrin 1 (TRPA1) antagonists: ligand-based discovery, activity in a rodent asthma model, and mechanism-of …

…, S Ciblat, C Sturino, Y Chen, B Hu, A Lu… - Journal of Medicinal …, 2021 - ACS Publications
Transient receptor potential ankyrin 1 (TRPA1) is a nonselective calcium-permeable ion
channel highly expressed in the primary sensory neurons functioning as a polymodal sensor for …

Perillaldehyde, a potential preservative agent in foods: Assessment of antifungal activity against microbial spoilage of cherry tomatoes

J Tian, X Zeng, A Lü, A Zhu, X Peng, Y Wang - LWT-Food Science and …, 2015 - Elsevier
The application of natural preservatives has recently become a very attractive method of
controlling postharvest decay. The objective of this study was to test the antifungal properties of …

First report of Vibrio vulnificus infection in grass carp Ctenopharyngodon idellus in China

R Liu, Z Lian, X Hu, A Lü, J Sun, C Chen, X Liu, Y Song… - Aquaculture, 2019 - Elsevier
Vibrio vulnificus infections have resulted in great economic losses in intensive aquaculture
in China. However, very little was reported on the characterization of pathogenic V. vulnificus …

Detection and characterization of Aeromonas salmonicida subsp. salmonicida infection in crucian carp Carassius auratus

Z Lian, J Bai, X Hu, A Lü, J Sun, Y Guo… - Veterinary research …, 2020 - Springer
Aeromonas salmonicida is one of the most important pathogens in salmonids and non-salmonids
species. Nevertheless, very little was reported in cyprinids about A. salmonicida …

Isolation and characterization of Citrobacter spp. from the intestine of grass carp Ctenopharyngodon idellus

A Lü, X Hu, L Zheng, A Zhu, C Cao, J Jiang - Aquaculture, 2011 - Elsevier
Citrobacter gastroenteritis became an increasingly significant health problem in intensive
aquaculture in China. In this study, three bacterial strains were isolated from the intestinal tract …