Whole-genome resequencing reveals world-wide ancestry and adaptive introgression events of domesticated cattle in East Asia

N Chen, Y Cai, Q Chen, R Li, K Wang, Y Huang… - Nature …, 2018 - nature.com
Cattle domestication and the complex histories of East Asian cattle breeds warrant further
investigation. Through analysing the genomes of 49 modern breeds and eight East Asian …

High‐resolution 3D NIR‐II photoacoustic imaging of cerebral and tumor vasculatures using conjugated polymer nanoparticles as contrast agent

B Guo, J Chen, N Chen, E Middha, S Xu… - Advanced …, 2019 - Wiley Online Library
Exogenous contrast‐agent‐assisted NIR‐II optical‐resolution photoacoustic microscopy
imaging (ORPAMI) holds promise to decipher wide‐field 3D biological structures with deep …

Ancient genomes reveal tropical bovid species in the Tibetan Plateau contributed to the prevalence of hunting game until the late Neolithic

N Chen, L Ren, L Du, J Hou… - Proceedings of the …, 2020 - National Acad Sciences
Local wild bovids have been determined to be important prey on the northeastern Tibetan
Plateau (NETP), where hunting game was a major subsistence strategy until the late Neolithic, …

Evidence for early domestic yak, taurine cattle, and their hybrids on the Tibetan Plateau

N Chen, Z Zhang, J Hou, J Chen, X Gao, L Tang… - Science …, 2023 - science.org
Domestic yak, cattle, and their hybrids are fundamental to herder survival at high altitudes
on the Tibetan Plateau. However, little is known about their history. Bos remains are …

[HTML][HTML] Optical-resolution photoacoustic microscopy for monitoring vascular normalization during anti-angiogenic therapy

HC Zhou, N Chen, H Zhao, T Yin, J Zhang, W Zheng… - Photoacoustics, 2019 - Elsevier
Monitoring the changes in tumor vascularity is important for anti-angiogenic therapy assessment
with therapeutic implications. However, monitoring vascularity is quite challenging due …

Assessing genomic diversity and signatures of selection in Jiaxian Red cattle using whole-genome sequencing data

X Xia, S Zhang, H Zhang, Z Zhang, N Chen, Z Li, H Sun… - BMC genomics, 2021 - Springer
Background Native cattle breeds are an important source of genetic variation because they
might carry alleles that enable them to adapt to local environment and tough feeding …

Responsive multifunctional hydrogels emulating the chronic wounds healing cascade for skin repair

…, L Long, S He, Z Wang, Y Liu, L Yang, N Chen… - Journal of Controlled …, 2023 - Elsevier
It remains challenging to cure chronic diabetic wounds due to its' harsh microenvironment
and poor tissue regeneration ability. At present, bacteria elimination, inflammatory response …

Global genetic diversity, introgression, and evolutionary adaptation of indicine cattle revealed by whole genome sequencing

N Chen, X Xia, Q Hanif, F Zhang, R Dang… - Nature …, 2023 - nature.com
Indicine cattle, also referred to as zebu (Bos taurus indicus), play a central role in pastoral
communities across a wide range of agro-ecosystems, from extremely hot semiarid regions to …

Frequent intra-and inter-species introgression shapes the landscape of genetic variation in bread wheat

H Cheng, J Liu, J Wen, X Nie, L Xu, N Chen, Z Li… - Genome biology, 2019 - Springer
Background Bread wheat is one of the most important and broadly studied crops. However,
due to the complexity of its genome and incomplete genome collection of wild populations, …

BGVD: an integrated database for bovine sequencing variations and selective signatures

N Chen, W Fu, J Zhao, J Shen, Q Chen… - Genomics …, 2020 - academic.oup.com
Next-generation sequencing has yielded a vast amount of cattle genomic data for global
characterization of population genetic diversity and identification of genomic regions under …