There is great interest in tumor stem cells (TSCs) as potential therapeutic targets; however,
cancer therapies targeting TSCs are limited. A drawback is that TSC markers are often …

OBJECTIVE: Recent studies make remarks on the effect of variability in systolic blood
pressure (SBP) on the development of cardiovascular disease. The aim of this study was to …

Oxidative stress plays a critical role in liver tissue damage and in hepatocellular carcinoma (HCC)
initiation and progression. However, the mechanisms that regulate autophagy and …

Background: Microplastics (MPs) are small particles of plastic ( ≤ 5 mm in diameter). In recent
years, oral exposure to MPs in living organisms has been a cause of concern. Leaky gut …

To investigate the acute effects of the coronavirus disease 2019 (COVID-19) on the lifestyle
and metabolic parameters in patients with type 2 diabetes mellites. This cross-sectional and …

Paneth cells are a highly specialized population of intestinal epithelial cells located in the
crypt adjacent to Lgr5 + stem cells, from which they differentiate through a process that …

OBJECTIVE Recent study has suggested that not only the presence of hypertension but
also the variability in systolic blood pressure (SBP) are risk factors for vascular disease and …

Background Diabetes mellitus increases the excretion of urinary glucose from the renal
glomeruli due to elevated blood glucose levels. In the renal tubules, SGLT2 is expressed and …

Background Sarcopenia has reportedly been associated with increased risk of mortality in
general populations. However, few studies have investigated the association between …

In recent years, sarcopenic obesity has been considered central pathological factors in
diabetes. This study aimed to compare the effect of luseogliflozin, a sodium-glucose co-…